Analysis of the SUMO2 Proteome during HSV-1 Infection

• Published in: PLoS pathogens Vol. 11; no. 7; p. e1005059
• Main Authors: Sloan, Elizabeth, Tatham, Michael H, Groslambert, Marine, Glass, Mandy, Orr, Anne, Hay, Ronald T, Everett, Roger D
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.07.2015; Public Library of Science (PLoS)
• Subjects: Cell Line; Experiments; Gene expression; Gene Expression Regulation, Viral - genetics; Herpes viruses; Herpesvirus 1, Human; Host-Pathogen Interactions; Humans; Infections; Medical research; Proteins; Proteome - genetics; Proteome - metabolism; Proteomics - methods; Signal transduction; Small Ubiquitin-Related Modifier Proteins - genetics; Small Ubiquitin-Related Modifier Proteins - immunology; Small Ubiquitin-Related Modifier Proteins - metabolism; Transcription Factors - metabolism; Tumor Suppressor Proteins - metabolism; Viral infections; Viral Proteins - metabolism

Covalent linkage to members of the small ubiquitin-like (SUMO) family of proteins is an important mechanism by which the functions of many cellular proteins are regulated. Sumoylation has roles in the control of protein stability, activity and localization, and is involved in the regulation of trans...