Transplantation of human menstrual blood stem cells to treat premature ovarian failure in mouse model

• Published in: Stem cells and development Vol. 23; no. 13; p. 1548
• Main Authors: Liu, Te, Huang, Yongyi, Zhang, Jian, Qin, Wenxing, Chi, Huiying, Chen, Jiulin, Yu, Zhihua, Chen, Chuan
• Format: Journal Article
• Language: English
• Published: United States 01.07.2014
• Subjects: Animals; Biomarkers - metabolism; Cell Survival; Cells, Cultured; Disease Models, Animal; Female; Humans; Menstruation; Mesenchymal Stromal Cells - metabolism; Mice, Inbred C57BL; Organ Size; Ovary - metabolism; Ovary - pathology; Ovary - secretion; Primary Ovarian Insufficiency - therapy; Stem Cell Transplantation; Transcriptome

The incidence of premature ovarian failure (POF), also known as ovarian insufficiency, has been increasing in recent years. Although some treatments are currently available, improved treatment strategies are urgently required. Many researchers have reported that human endometrial stem cells (HuMenSC...