Beta-blockade causes a reduction in the frequency spectrum of VF but improves resuscitation outcome: A potential limitation of quantitative waveform measures

• Published in: Resuscitation Vol. 83; no. 4; pp. 511 - 516
• Main Authors: Sherman, Lawrence, Niemann, James, Youngquist, Scott T., Shah, Atman P., Rosborough, John P.
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 01.04.2012
• Subjects: Adrenergic beta-Antagonists - pharmacology; Animals; Cardiac arrest; Cardiopulmonary resuscitation; Cardiopulmonary Resuscitation - methods; Confidence Intervals; Defibrillation; Disease Models, Animal; Electric Countershock; Electrocardiography - drug effects; Electrocardiography - methods; Emergency; Heart Arrest - mortality; Heart Arrest - therapy; Labetalol - pharmacology; Male; Metoprolol - pharmacology; Outcome; Random Allocation; Statistics, Nonparametric; Survival Rate; Sus scrofa; Swine; Time Factors; Ventricular Fibrillation - diagnosis; Ventricular Fibrillation - drug therapy; VF analysis; VF analysis; Defibrillation; Cardiopulmonary resuscitation; Outcome; Cardiac arrest

Methods to identify appropriate treatments for the various stages of ventricular fibrillation (VF) involve differentiating groups of subjects who will respond to defibrillation with return of spontaneous circulation (ROSC) and those who require other therapies (e.g., CPR, drugs) prior to defibrillat...