Nuclear receptor PPARγ-regulated monoacylglycerol O-acyltransferase 1 (MGAT1) expression is responsible for the lipid accumulation in diet-induced hepatic steatosis - Lee, Yoo Jeong; Ko, Eun Hee; Kim, Ji Eun; Kim, Eunha; Lee, Hyemin; Choi, Hyeonjin; Yu, Jung Hwan; Kim, Hyo Jung; Seong, Je-Kyung; Kim, Kyung-Sup; Kim, Jae-woo (Proceedings of the National Academy of Sciences - PNAS, 2012)
Keywords: Acyltransferases - biosynthesis; Adenoviridae - genetics; Animal Feed; Animals; Biological Sciences; Cell Nucleus - metabolism; chromatin; Fatty acids; Fatty liver; Fatty Liver - metabolism; gel electrophoresis; Gene expression regulation; Gene Expression Regulation, Enzymologic; genes; glucose tolerance; Hepatocytes; high fat diet; Lipid metabolism; Lipids; Lipids - chemistry; Liver; luciferase; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; microarray technology; Models, Biological; Obesity; PPAR gamma - biosynthesis; PPAR gamma - metabolism; precipitin tests; Sterol Regulatory Element Binding Protein 1 - genetics; Toll-Like Receptor 4 - genetics; triacylglycerols; Triglycerides; weight loss