Rationale and design of the Women's Ischemia Trial to Reduce Events in Nonobstructive CAD (WARRIOR) trial

• Published in: The American heart journal Vol. 237; pp. 90 - 103
• Main Authors: Handberg, Eileen M., Merz, C. Noel Bairey, Cooper-Dehoff, Rhonda M., Wei, Janet, Conlon, Michael, Lo, Margaret C., Boden, William, Frayne, Susan M., Villines, Todd, Spertus, John A., Weintraub, William, O'Malley, Patrick, Chaitman, Bernard, Shaw, Leslee J., Budoff, Matthew, Rogatko, Andre, Pepine, Carl J.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2021; Elsevier Limited
• Subjects: Acute coronary syndromes; Angina; Angina pectoris; Angiography; Angiotensin; Angiotensin-converting enzyme inhibitors; Asymptomatic; Biomarkers; Cardiac catheterization; Cardiovascular disease; Consents; Coronary artery; Coronary artery disease; Data capture; Enzyme inhibitors; Grants; Guidelines; Heart attacks; Heart diseases; Hospitalization; Intubation; Ischemia; Medical imaging; Pain; Patients; Peptidyl-dipeptidase A; Quality of life; Resource consumption; Resource management; Scholarships & fellowships; Signs and symptoms; Statins; Strategy; Stroke; Symptom management; Womens health; Los Angeles California; United States > US; California

Approximately half of all women with anginal symptoms and/or signs of ischemia and no obstructive coronary artery disease (INOCA) referred for coronary angiography have elevated risk for major adverse cardiac events (MACE), poor quality of life and resource consumption. Yet, guidelines focus on symp...