Improved monoterpene biotransformation with Penicillium sp. by use of a closed gas loop bioreactor

• Published in: Journal of industrial microbiology & biotechnology Vol. 36; no. 6; pp. 827 - 836
• Main Authors: Pescheck, Michael, Mirata, Marco Antonio, Brauer, Bianca, Krings, Ulrich, Berger, Ralf Günter, Schrader, Jens
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Berlin/Heidelberg : Springer-Verlag 01.06.2009; Springer-Verlag; Springer; Oxford University Press
• Subjects: Actinidia - microbiology; Biochemistry; Bioconversions. Hemisynthesis; Bioinformatics; Biological and medical sciences; Biomedical and Life Sciences; Bioreactors; Biotechnology; Biotransformation; Chemical reactors; Culture Techniques; Fundamental and applied biological sciences. Psychology; Fungi; Gases - metabolism; Genetic Engineering; Inorganic Chemistry; Life Sciences; Metabolism; Methods. Procedures. Technologies; Microbiology; Microorganisms; Monoterpenes; Original Paper; Penicillium; Penicillium - isolation & purification; Penicillium - metabolism; Penicillium digitatum; Process engineering; Prokaryotes; Studies; Terpenes - metabolism; Toxicity; Various methods and equipments; Gas loop; Biotransformation; Verbenone; α-Terpineol; Fungi; Bioreactor; Penicillium; Monoterpene; Fungi Imperfecti; α-Terpincol

A closed gas loop bioprocess was developed to improve fungal biotransformation of monoterpenes. By circulating monoterpene-saturated process gas, the evaporative loss of the volatile precursor from the medium during the biotransformation was avoided. Penicillium solitum, isolated from kiwi, turned o...