Recombinant CD4-selected human immunodeficiency virus type 1 variants with reduced gp120 affinity for CD4 and increased cell fusion capacity

• Published in: Journal of Virology Vol. 65; no. 9; pp. 4777 - 4785
• Main Authors: MCKEATING, J, BALFE, P, CLAPHAM, P, WEISS, R. A
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.09.1991
• Subjects: AIDS/HIV; Amino Acid Sequence; Biological and medical sciences; CD4 antigen; CD4 Antigens - genetics; CD4 Antigens - metabolism; Cell Fusion; Cytopathogenic Effect, Viral; DNA; Fundamental and applied biological sciences. Psychology; glycoprotein gp120; HIV Antibodies - immunology; HIV Envelope Protein gp120 - genetics; HIV Envelope Protein gp120 - immunology; HIV Envelope Protein gp120 - metabolism; HIV-1 - growth & development; HIV-1 - metabolism; human immunodeficiency virus 1; Humans; In Vitro Techniques; Microbiology; Molecular Sequence Data; Mutation; neutralization; Neutralization Tests; nucleotide sequence; Protein Binding; Recombinant Proteins - chemistry; Recombinant Proteins - metabolism; replication; Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains; site-directed mutagenesis; Solubility; Structure-Activity Relationship; Virology; Virus Replication; HIV-1 virus; Retroviridae; Glycoproteins; Host; Cell fusion; Host virus relation; Virus; Variant; Sensitivity resistance; Lentivirinae; Affinity; Cytopathology; Replication; Human immunodeficiency virus; Mutation; Recombinant protein; Neutralization; Biological receptor

Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue JVI About JVI Subscribers Authors Reviewers Advertisers Inquiries from...