A venous mechanism of ventriculomegaly shared between traumatic brain injury and normal ageing

• Published in: Brain (London, England : 1878) Vol. 143; no. 6; pp. 1843 - 1856
• Main Authors: Aso, Toshihiko, Sugihara, Genichi, Murai, Toshiya, Ubukata, Shiho, Urayama, Shin-ichi, Ueno, Tsukasa, Fujimoto, Gaku, Thuy, Dinh Ha Duy, Fukuyama, Hidenao, Ueda, Keita
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.06.2020
• Subjects: Adult; Aged; Aging - pathology; Aging - physiology; Brain Injuries, Traumatic - diagnostic imaging; Brain Injuries, Traumatic - metabolism; Brain Injuries, Traumatic - physiopathology; Cerebral Ventricles - pathology; Editor's Choice; Female; Femoral Vein; Humans; Hydrocephalus - etiology; Hydrocephalus - metabolism; Hydrocephalus - physiopathology; Hydrocephalus, Normal Pressure - diagnostic imaging; Hydrocephalus, Normal Pressure - pathology; Iliac Vein; Magnetic Resonance Imaging - methods; Male; Middle Aged; Nervous System Malformations - pathology; Original; Popliteal Vein; Tomography, X-Ray Computed - methods; traumatic brain injury; ventricular enlargement; normal pressure hydrocephalus; venous drainage; brain ageing

Recently, age-related timing dissociation between the superficial and deep venous systems has been observed; this was particularly pronounced in patients with normal pressure hydrocephalus, suggesting a common mechanism of ventriculomegaly. Establishing the relationship between venous drainage and v...