Arteries and veins: making a difference with zebrafish

• Published in: Nature reviews. Genetics Vol. 3; no. 9; pp. 674 - 682
• Main Authors: Lawson, Nathan D., Weinstein, Brant M.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.09.2002; Nature Publishing Group
• Subjects: Agriculture; Animal Genetics and Genomics; Animals; Animals, Genetically Modified; Arteries - physiology; Biomedical and Life Sciences; Biomedicine; Blood vessels; Cancer Research; Chickens; Coronary vessels; Danio rerio; Embryos; Endothelium, Vascular - physiology; Gene Function; Human Genetics; Ligands; Mice; Morphogenesis; Physiology; review-article; Veins & arteries; Veins - physiology; Zebrafish - embryology; Zebrafish - genetics; Zebrafish - physiology

Key Points One of the most fundamental distinctions between blood vessels is that between arteries and veins. These two types of vessel are structurally different and have long been functionally defined by the direction of the flow of blood that they carry. Recent work indicates that the endothelial...