Echocardiographic Findings in Autosomal Dominant Polycystic Kidney Disease

• Published in: The New England journal of medicine Vol. 319; no. 14; pp. 907 - 912
• Main Authors: Hossack, Kenneth F, Leddy, Cheryl L, Johnson, Ann M, Schrier, Robert W, Gabow, Patricia A
• Format: Journal Article
• Language: English
• Published: Boston, MA Massachusetts Medical Society 06.10.1988
• Subjects: Abdomen; Adult; Age; Aorta; Aortic Valve Insufficiency - diagnosis; Aortic Valve Insufficiency - etiology; Biological and medical sciences; Cysts; Doppler effect; Echocardiography; Extracellular matrix; Female; Genes, Dominant; Heart diseases; Heart Valve Diseases - diagnosis; Heart Valve Diseases - etiology; Humans; Kidney diseases; Kidney transplantation; Kidneys; Male; Malformations of the urinary system; Medical sciences; Medicine; Mitral Valve Insufficiency - diagnosis; Mitral Valve Insufficiency - etiology; Mitral Valve Prolapse - diagnosis; Mitral Valve Prolapse - etiology; Nephrology. Urinary tract diseases; Polycystic kidney; Polycystic Kidney Diseases - complications; Polycystic Kidney Diseases - genetics; Population; Sodium; Tricuspid Valve Insufficiency - diagnosis; Tricuspid Valve Insufficiency - etiology; Values; Urinary system disease; Echocardiography; Cardiac valvular disease; Malformation; Polycystic kidney; Ultrasonic investigation; Cardiovascular disease; Kidney
• ISSN: 0028-4793; 1533-4406
• DOI: 10.1056/NEJM198810063191404

Echocardiography, including Doppler analysis, was performed to assess the prevalence of cardiac abnormalities in 163 patients with autosomal dominant polycystic kidney disease, 130 unaffected family members, and 100 control subjects. In these three groups, the prevalence of mitral-valve prolapse was...