The crescent-like Golgi ribbon is shaped by the Ajuba/PRMT5/Aurora-A complex-modified HURP

• Published in: Cell communication and signaling Vol. 21; no. 1; pp. 156 - 16
• Main Authors: Chiu, Shao-Chih, Yang, Xin-Ting, Wei, Tong-You Wade, Liao, Yu-Ting Amber, Chen, Jo-Mei Maureen, Kuo, Yi-Chun, Liu, Chun-Chih Jared, Cheng, Chiao-Yun, Huang, Yu-Ting Jenny, Huang, Yun-Ru Jaoying, Wu, He-Lian Joe, Wan, Chang-Xin, Tsai, Jia-Rung, Yu, Chang-Tze Ricky
• Format: Journal Article
• Language: English
• Published: England BioMed Central 27.06.2023; BMC
• Subjects: Adaptor proteins; Ajuba; Antibodies; ARF1; Aurora-A; Cell culture; Cell cycle; Dynein; Genomes; Golgi apparatus; Golgi ribbon; HURP; Immunofluorescence; Kinases; Mammalian cells; Membranes; Mutagenesis; Penicillin; Peptides; Phosphorylation; Plasmids; PRMT5; Protein arginine methyltransferase; Proteins; Site-directed mutagenesis; Taiwan; PRMT5; HURP; ARF1; Golgi ribbon; Aurora-A; Ajuba

Golgi apparatus (GA) is assembled as a crescent-like ribbon in mammalian cells under immunofluorescence microscope without knowing the shaping mechanisms. It is estimated that roughly 1/5 of the genes encoding kinases or phosphatases in human genome participate in the assembly of Golgi ribbon, refle...