Autotaxin Has Lysophospholipase D Activity Leading to Tumor Cell Growth and Motility by Lysophosphatidic Acid Production - Umezu-Goto, Makiko; Kishi, Yasuhiro; Taira, Akitsu; Hama, Kotaro; Dohmae, Naoshi; Takio, Koji; Yamori, Takao; Mills, Gordon B.; Inoue, Keizo; Aoki, Junken; Arai, Hiroyuki (The Journal of cell biology, 2002)
Keywords: Acid production; Animals; Cattle; Cell Division - drug effects; Cell growth; Cell lines; Cell motility; Cell Movement - drug effects; Cells; Cellular biology; Chemotaxis; Cultured cells; Glucose-6-Phosphate Isomerase - analysis; Glucose-6-Phosphate Isomerase - metabolism; Glucose-6-Phosphate Isomerase - pharmacology; Glycoproteins - analysis; Glycoproteins - metabolism; Glycoproteins - pharmacology; Lipids; Lysophospholipids; Lysophospholipids - metabolism; Multienzyme Complexes; Neoplasms - enzymology; Neoplasms - pathology; Phosphodiesterase I; Phosphoric Diester Hydrolases - analysis; Phosphoric Diester Hydrolases - metabolism; Phosphoric Diester Hydrolases - pharmacology; Pyrophosphatases; Rats; Receptors; Recombinant Proteins - pharmacology; Substrate Specificity; Tumor Cells, Cultured; Tumors