The effects of sodium butyrate supplementation on the expression levels of PGC-1α, PPARα, and UCP-1 genes, serum level of GLP-1, metabolic parameters, and anthropometric indices in obese individuals on weight loss diet: a study protocol for a triple-blind, randomized, placebo-controlled clinical trial - Amiri, Parichehr; Hosseini, Seyed Ahmad; Roshanravan, Neda; Saghafi-Asl, Maryam; Tootoonchian, Mitra (Current controlled trials in cardiovascular medicine, 2023)
Keywords: Adolescent; Adult; Anthropometry; Appetite; Bacteria; Body composition; Body measurements; Butyric Acid - therapeutic use; Clinical trials; Consent; Data collection; Diabetes; Diet; Diet, Reducing; Dietary Supplements - adverse effects; Energy; Energy metabolism genes; Ethics; Glucagon-Like Peptide 1 - therapeutic use; Glucose; Humans; Medical research; Metabolism; Metabolites; Microbiota; Middle Aged; Nutrition research; Obesity; Obesity - diagnosis; Obesity - drug therapy; Obesity - genetics; PPAR alpha - genetics; PPAR alpha - metabolism; PPAR alpha - therapeutic use; Randomized controlled trial; Randomized Controlled Trials as Topic; Sample size; Sodium butyrate; Study Protocol; Transcription Factors; Triglycerides; Uncoupling Protein 1 - genetics; Weight control; Young Adult; Appetite; Obesity; Sodium butyrate; Randomized controlled trial; Energy metabolism genes