Role of aneuploidy screening in preimplantation genetic testing for monogenic diseases in young women

• Published in: Fertility and sterility Vol. 111; no. 5; pp. 928 - 935
• Main Authors: Hou, Wenhui, Xu, Yan, Li, Rong, Song, Junli, Wang, Jing, Zeng, Yanhong, Pan, Jiafu, Zhou, Canquan, Xu, Yanwen
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2019
• Subjects: Adult; Aneuploidy; Cohort Studies; Female; genetic testing; Genetic Testing - methods; Humans; in vitro fertilization; live birth; oocyte retrieval; Oocyte Retrieval - methods; Pregnancy; Pregnancy Outcome - epidemiology; Pregnancy Outcome - genetics; Preimplantation Diagnosis - methods; Retrospective Studies; Young Adult; Aneuploidy; oocyte retrieval; in vitro fertilization; live birth; genetic testing

To investigate whether aneuploidy screening in preimplantation genetic testing (PGT) for monogenic diseases improves the ongoing pregnancy/live birth rate of single frozen/thawed embryo transfer (FET) cycles in young women. Retrospective cohort study. Single university-based fertility center. From J...