The Role of Reactive Oxygen Species in Mesenchymal Stem Cell Adipogenic and Osteogenic Differentiation: A Review

• Published in: Stem cells and development Vol. 24; no. 10; pp. 115 - 1163
• Main Authors: Atashi, Fatemeh, Modarressi, Ali, Pepper, Michael S.
• Format: Journal Article
• Language: English
• Published: United States Mary Ann Liebert, Inc 15.05.2015
• Subjects: Adipocytes - cytology; Adipogenesis - physiology; Animals; Cell Differentiation - physiology; Comprehensive Review; Humans; Mesenchymal Stromal Cells - cytology; Osteogenesis - physiology; Reactive Oxygen Species - metabolism

Mesenchymal stromal cells (MSCs) are promising candidates for tissue engineering and regenerative medicine. The multipotent stem cell component of MSC isolates is able to differentiate into derivatives of the mesodermal lineage including adipocytes, osteocytes, chondrocytes, and myocytes. Many commo...