Structure and assembly of macromolecular lipid complexes composed of globular micelles
Negatively-stained preparations of various mixtures of lecithin, cholesterol and saponin have been investigated by electron microscopy. Lamellar, tubular, hexagonal and helical structures were observed and it has been concluded that many of these structures can be satisfactorily interpreted only in...
Saved in:
Published in | Journal of molecular biology Vol. 8; no. 5; pp. 727,IN12 - 748,IN22 |
---|---|
Main Authors | , |
Format | Journal Article |
Language | English |
Published |
England
Elsevier Ltd
01.01.1964
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Negatively-stained preparations of various mixtures of lecithin, cholesterol and saponin have been investigated by electron microscopy. Lamellar, tubular, hexagonal and helical structures were observed and it has been concluded that many of these structures can be satisfactorily interpreted only in terms of small globular lipid micelles. It is postulated that two types of micelle are present : one containing primarily lecithin and cholesterol, and the other containing mainly saponin and cholesterol, with measurable diameters of about 40 Å and about 35 Å respectively. These micelles appear to aggregate spontaneously in aqueous dispersions to form the observed complex structures, and it is thought that hydrogen bonds and electrostatic interactions between micelles are responsible for the stability of the complete assemblies. Helical structures prepared using a short-chain synthetic lecithin contain subunits of correspondingly reduced dimensions. The tubular structures present in mixtures of lecithin and cholesterol are similar in appearance and dimensions to bacterial flagella, while helices in mixtures of ovolecithin, cholesterol and saponin resemble tobacco mosaic viruses. Some of the implications of these observations are discussed, and it is suggested that small globular micelles, as well as bimolecular leaflets, may function as building blocks in the formation of biological structures containing lipids. |
---|---|
AbstractList | Negatively-stained preparations of various mixtures of lecithin, cholesterol and saponin have been investigated by electron microscopy. Lamellar, tubular, hexagonal and helical structures were observed and it has been concluded that many of these structures can be satisfactorily interpreted only in terms of small globular lipid micelles. It is postulated that two types of micelle are present : one containing primarily lecithin and cholesterol, and the other containing mainly saponin and cholesterol, with measurable diameters of about 40 Å and about 35 Å respectively. These micelles appear to aggregate spontaneously in aqueous dispersions to form the observed complex structures, and it is thought that hydrogen bonds and electrostatic interactions between micelles are responsible for the stability of the complete assemblies. Helical structures prepared using a short-chain synthetic lecithin contain subunits of correspondingly reduced dimensions. The tubular structures present in mixtures of lecithin and cholesterol are similar in appearance and dimensions to bacterial flagella, while helices in mixtures of ovolecithin, cholesterol and saponin resemble tobacco mosaic viruses. Some of the implications of these observations are discussed, and it is suggested that small globular micelles, as well as bimolecular leaflets, may function as building blocks in the formation of biological structures containing lipids. |
Author | Glauert, Audrey M. Lucy, J.A. |
Author_xml | – sequence: 1 givenname: J.A. surname: Lucy fullname: Lucy, J.A. – sequence: 2 givenname: Audrey M. surname: Glauert fullname: Glauert, Audrey M. |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/14187398$$D View this record in MEDLINE/PubMed |
BookMark | eNqFkE1LxDAQhoMoun78BKUn0UM1k6ZtchIRv0Dw4Mc1pMlUImmzJq3ov3e7u-jR08zhmXlnnl2y2YceCTkEegYUqvMnShnLmSiqk4qfCgoMcrZBZkCFzEVViE0y-0V2yG5K75TSsuBim-wAB1EXUszI69MQRzOMETPd20ynhF3jv7PQZp02MXTBoxm9jpl3c2czE7q5xy9Myy4ktBP65kOzhDpn0HtM-2Sr1T7hwbrukZeb6-eru_zh8fb-6vIhN1zWQw7aIK9NSznlhdDWtsIKzsEUDOq2BMlaCQ1SVlFZS66FqIE2si0tA4CSFXvkeLV3HsPHiGlQnUvTCbrHMCYlirKupawWYLkCFz-lFLFV8-g6Hb8VUDUJVUuharKlKq6WQtUUcLQOGJsO7d_U2uACuFgBuHjz02FUyTjsDVoX0QzKBvdPxA_jEodH |
CitedBy_id | crossref_primary_10_1016_0005_2736_70_90189_6 crossref_primary_10_1016_S0009_3084_02_00002_6 crossref_primary_10_1016_S0021_9258_18_33812_2 crossref_primary_10_1016_S0022_2836_67_80003_2 crossref_primary_10_1016_S0022_2275_20_43097_4 crossref_primary_10_1038_293488a0 crossref_primary_10_1007_BF00412870 crossref_primary_10_1002_ar_1091540306 crossref_primary_10_1007_BF00455926 crossref_primary_10_1016_S0022_5320_70_90024_9 crossref_primary_10_1007_BF00280951 crossref_primary_10_1007_BF00339787 crossref_primary_10_1111_j_1365_2818_1969_tb00645_x crossref_primary_10_1007_BF01686643 crossref_primary_10_1016_0009_3084_68_90004_2 crossref_primary_10_1002_jcp_1040670214 crossref_primary_10_1016_0006_2952_68_90132_9 crossref_primary_10_1016_0042_6822_65_90195_9 crossref_primary_10_1007_BF01250385 crossref_primary_10_1016_0006_291X_68_90124_1 crossref_primary_10_1016_S0021_9258_19_69159_3 crossref_primary_10_1007_BF00408528 crossref_primary_10_1016_S0022_5320_67_80084_4 crossref_primary_10_1079_PNS19650031 crossref_primary_10_1016_S0022_5320_69_90023_9 crossref_primary_10_1016_0014_4827_66_90410_1 crossref_primary_10_1007_BF01004804 crossref_primary_10_1016_S0368_1319_68_80061_4 crossref_primary_10_1016_0014_5793_94_00881_7 crossref_primary_10_1016_S0021_9258_18_83408_1 crossref_primary_10_1016_0021_9150_80_90101_X crossref_primary_10_1016_S0264_410X_99_00052_3 crossref_primary_10_1111_j_1365_2818_1968_tb00597_x crossref_primary_10_1016_0079_6107_66_90005_8 crossref_primary_10_1016_S0022_2836_64_80115_7 crossref_primary_10_1016_0079_6107_70_90014_3 crossref_primary_10_1016_0022_5320_72_90093_7 crossref_primary_10_1111_j_1365_3032_1984_tb00679_x crossref_primary_10_1038_227815a0 crossref_primary_10_1002_jps_2600620713 crossref_primary_10_1111_j_1749_6632_1965_tb45412_x crossref_primary_10_1126_science_1114345 crossref_primary_10_1128_jb_104_2_948_965_1970 crossref_primary_10_1007_BF00408998 crossref_primary_10_1016_0079_6107_68_90019_9 crossref_primary_10_1016_0022_1910_72_90092_3 crossref_primary_10_1016_0022_2836_69_90135_1 crossref_primary_10_1016_0306_3623_86_90088_1 crossref_primary_10_1002_jobm_19720120302 crossref_primary_10_1016_0005_2736_70_90121_5 crossref_primary_10_1016_0022_2836_70_90407_9 crossref_primary_10_1016_0306_3623_89_90003_7 crossref_primary_10_1016_S0022_5320_67_80117_5 crossref_primary_10_1016_0005_2736_67_90055_7 crossref_primary_10_1016_S0022_5320_68_90025_7 crossref_primary_10_1016_S0022_5320_70_80003_X crossref_primary_10_1016_0304_4157_72_90013_5 crossref_primary_10_1038_204156a0 crossref_primary_10_1016_0169_4758_96_10022_3 crossref_primary_10_1016_0378_5955_86_90061_4 crossref_primary_10_1016_S0022_2836_65_80272_8 crossref_primary_10_1126_science_148_3670_638 crossref_primary_10_1002_aja_1001750206 crossref_primary_10_1016_0739_6260_88_90037_8 crossref_primary_10_1016_0005_2736_68_90104_1 crossref_primary_10_1016_S0022_2275_20_39239_7 crossref_primary_10_1016_S0015_6264_67_83213_9 crossref_primary_10_1128_jb_98_2_767_773_1969 crossref_primary_10_1016_0005_2736_70_90060_X crossref_primary_10_1016_0014_4827_67_90356_4 crossref_primary_10_1002_jobm_3630120302 crossref_primary_10_1007_BF02116579 crossref_primary_10_1016_S0021_9258_18_97388_6 crossref_primary_10_1016_S0022_5320_70_90128_0 crossref_primary_10_1016_j_xpro_2021_100669 crossref_primary_10_1111_j_1399_3054_1970_tb06407_x crossref_primary_10_1136_thx_24_5_511 crossref_primary_10_1016_0304_4157_74_90007_0 crossref_primary_10_1126_science_153_3743_1491 crossref_primary_10_1007_BF02906284 crossref_primary_10_1016_0025_5564_67_90015_6 crossref_primary_10_1002_ar_1091520312 crossref_primary_10_1007_BF00344549 crossref_primary_10_1038_235090a0 crossref_primary_10_1016_j_bpj_2012_03_071 crossref_primary_10_1016_0014_4827_65_90218_1 crossref_primary_10_1007_BF00606221 crossref_primary_10_1038_213833b0 crossref_primary_10_1016_0042_6822_66_90173_5 crossref_primary_10_1111_j_1699_0463_1973_tb03561_x crossref_primary_10_1016_0009_3084_72_90053_9 crossref_primary_10_1080_15421407008083489 crossref_primary_10_1016_0005_2760_70_90055_X crossref_primary_10_1016_S0022_5320_79_80053_2 crossref_primary_10_1007_BF03259065 crossref_primary_10_1016_0739_6260_86_90046_8 crossref_primary_10_1016_0022_1902_75_80709_3 crossref_primary_10_1128_jb_133_2_932_941_1978 crossref_primary_10_1002_aja_1001320108 crossref_primary_10_1016_S0022_5320_69_90021_5 crossref_primary_10_3109_02713688708997562 crossref_primary_10_1007_BF02703373 crossref_primary_10_1016_0022_5193_70_90132_3 crossref_primary_10_1016_S0300_9084_79_80205_9 crossref_primary_10_1016_0022_5193_64_90080_3 crossref_primary_10_1038_icb_1996_2 crossref_primary_10_1002_path_1700940122 crossref_primary_10_1016_0014_4835_77_90180_4 crossref_primary_10_1016_0002_9343_68_90091_0 crossref_primary_10_1016_S0022_5320_67_80041_8 crossref_primary_10_1111_j_1438_8677_1969_tb02273_x crossref_primary_10_1016_0005_2736_91_90388_O crossref_primary_10_1016_S0927_7765_02_00099_1 crossref_primary_10_1016_0005_2760_72_90041_0 crossref_primary_10_1016_0014_4827_69_90448_0 crossref_primary_10_1007_BF02702669 crossref_primary_10_1016_0005_2736_76_90511_3 crossref_primary_10_1016_0304_4157_77_90013_2 crossref_primary_10_1016_0047_7206_70_90043_9 crossref_primary_10_1128_jb_121_2_700_703_1975 crossref_primary_10_1128_jb_90_6_1750_1763_1965 crossref_primary_10_1016_S0300_9084_72_80209_8 crossref_primary_10_1007_BF00686121 crossref_primary_10_1016_0264_410X_95_00253_W crossref_primary_10_1016_S0021_9258_18_60713_6 crossref_primary_10_1016_S0021_9258_18_48257_9 crossref_primary_10_1016_S0022_5320_66_80091_6 crossref_primary_10_1016_0002_9343_65_90249_4 crossref_primary_10_1016_0005_2795_72_90089_X crossref_primary_10_1016_S0016_5085_74_80076_4 crossref_primary_10_1098_rspb_1968_0002 crossref_primary_10_1111_j_1749_6632_1972_tb54819_x crossref_primary_10_1242_jcs_19_1_33 crossref_primary_10_1007_BF00602349 crossref_primary_10_1016_0042_6822_72_90520_X crossref_primary_10_1016_S0021_9258_18_96263_0 crossref_primary_10_1007_BF00334276 crossref_primary_10_1128_jb_95_3_1153_1168_1968 crossref_primary_10_1016_0006_2952_66_90198_5 crossref_primary_10_1007_BF01254686 crossref_primary_10_1016_S0022_2836_65_80236_4 crossref_primary_10_1007_BF01072500 crossref_primary_10_1128_jb_90_4_1059_1072_1965 crossref_primary_10_1016_0021_9150_89_90123_8 crossref_primary_10_1006_meth_1999_0833 crossref_primary_10_1111_j_1600_065X_1991_tb00578_x crossref_primary_10_2307_1294362 crossref_primary_10_1111_j_1348_0421_1974_tb00946_x crossref_primary_10_1111_j_1469_185X_1965_tb00809_x crossref_primary_10_1111_j_1550_7408_1972_tb03441_x crossref_primary_10_1016_0009_3084_68_90032_7 crossref_primary_10_1007_BF00319722 crossref_primary_10_1007_BF01248037 crossref_primary_10_1007_BF01248036 crossref_primary_10_1016_0009_3084_68_90013_3 crossref_primary_10_1016_0304_4157_83_90002_3 crossref_primary_10_1016_0002_9343_67_90070_8 crossref_primary_10_1016_S0021_9258_18_96249_6 crossref_primary_10_1128_jb_103_1_238_243_1970 crossref_primary_10_1128_jb_93_5_1705_1721_1967 crossref_primary_10_1016_0002_9343_66_90031_3 |
Cites_doi | 10.1016/0042-6822(61)90366-X 10.1002/jcp.1030090209 10.1111/j.1365-2818.1963.tb02095.x 10.1083/jcb.4.4.495 10.1016/0042-6822(63)90143-0 10.1126/science.82.2115.44 10.1083/jcb.12.2.221 10.1038/1971326a0 10.1016/0012-1606(63)90141-6 10.1016/0006-3002(60)90771-X 10.1083/jcb.17.1.111 10.1016/0022-5193(63)90007-9 10.1007/BF01502567 10.1016/S0022-5320(63)80011-8 10.1083/jcb.17.2.443 10.1083/jcb.8.1.13 10.1002/jcp.1030170313 10.1042/bj0680352 10.1007/BF00406937 10.1038/1991262a0 10.1016/S0022-2836(62)80001-1 10.1016/0006-291X(61)90042-0 10.1016/S0022-2836(62)80110-7 10.1016/S0006-3495(63)86818-6 10.1002/jcp.1030170311 10.1016/0006-3002(59)90237-9 10.1161/01.CIR.26.5.1039 10.1098/rspb.1937.0008 10.1038/1941116a0 10.1038/196952a0 10.1042/bj0840611 10.1083/jcb.12.2.207 10.1042/bj0900133 10.1038/196953a0 |
ContentType | Journal Article |
Copyright | 1964 Academic Press Inc. (London) Ltd. |
Copyright_xml | – notice: 1964 Academic Press Inc. (London) Ltd. |
DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
DOI | 10.1016/S0022-2836(64)80121-2 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Chemistry Biology |
EISSN | 1089-8638 |
EndPage | 748,IN22 |
ExternalDocumentID | 10_1016_S0022_2836_64_80121_2 14187398 S0022283664801212 |
Genre | Journal Article |
GroupedDBID | --- --K --M -DZ -ET -~X .55 .GJ .~1 0R~ 186 1B1 1RT 1~. 1~5 29L 3O- 4.4 457 4G. 53G 5GY 5RE 5VS 7-5 71M 85S 8P~ 9JM AAAJQ AABNK AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AARKO AAXUO ABEFU ABFNM ABFRF ABGSF ABJNI ABLJU ABMAC ABOCM ABPPZ ABUDA ABXDB ABYKQ ACDAQ ACGFO ACGFS ACKIV ACNCT ACRLP ADBBV ADEZE ADFGL ADIYS ADMUD ADUVX AEBSH AEFWE AEHWI AEKER AENEX AFFNX AFKWA AFMIJ AFTJW AFXIZ AGEKW AGHFR AGRDE AGUBO AGYEJ AHHHB AHPSJ AI. AIEXJ AIKHN AITUG AJBFU AJOXV ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC CAG CJTIS COF CS3 DM4 DOVZS DU5 EBS EFBJH EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q G8K GBLVA GX1 HLW HMG HVGLF HX~ HZ~ H~9 IH2 IHE J1W K-O KOM LG5 LUGTX LX2 LZ5 M41 MO0 MVM N9A NEJ O-L O9- OAUVE OZT P-8 P-9 P2P PC. Q38 R2- RIG RNS ROL RPZ SBG SDF SDG SDP SES SEW SIN SPCBC SSI SSU SSZ T5K TWZ UQL VH1 VQA WH7 WUQ X7M XJT XOL XPP Y6R YQT YYP ZGI ZKB ZMT ZU3 ~G- ~KM 0SF AAHBH AAXKI ADVLN AFJKZ AKRWK CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
ID | FETCH-LOGICAL-c497t-1ace47cf040438addf8d8441c3217f5192f91be02609794a88710b9f5d2111523 |
ISSN | 0022-2836 |
IngestDate | Fri Aug 16 08:24:54 EDT 2024 Thu Sep 26 16:06:13 EDT 2024 Sat Sep 28 08:37:43 EDT 2024 Fri Feb 23 02:36:53 EST 2024 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 5 |
Keywords | MICROSCOPY, ELECTRON CHOLESTEROL SAPONINS LECITHINS EXPERIMENTAL LAB STUDY |
Language | English |
LinkModel | OpenURL |
MergedId | FETCHMERGED-LOGICAL-c497t-1ace47cf040438addf8d8441c3217f5192f91be02609794a88710b9f5d2111523 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
PMID | 14187398 |
PQID | 83577996 |
PQPubID | 23479 |
PageCount | 22 |
ParticipantIDs | proquest_miscellaneous_83577996 crossref_primary_10_1016_S0022_2836_64_80121_2 pubmed_primary_14187398 elsevier_sciencedirect_doi_10_1016_S0022_2836_64_80121_2 |
PublicationCentury | 1900 |
PublicationDate | 1964-01-01 |
PublicationDateYYYYMMDD | 1964-01-01 |
PublicationDate_xml | – month: 01 year: 1964 text: 1964-01-01 day: 01 |
PublicationDecade | 1960 |
PublicationPlace | England |
PublicationPlace_xml | – name: England |
PublicationTitle | Journal of molecular biology |
PublicationTitleAlternate | J Mol Biol |
PublicationYear | 1964 |
Publisher | Elsevier Ltd |
Publisher_xml | – name: Elsevier Ltd |
References | Barton, Glover (bib6) 1962; 84 Finean, Rumsby (bib17) 1963; 197 Lucy, J. A. & Dingle, J. T. (1964). In Dourmashkin, Dougherty, Harris (bib13) 1962; 194 ed. by R. M. C. Dawson … D. N. Rhodes, in the press. Stoeckenius, Schulman, Prince (bib45) 1960; 169 Bangham, Home (bib4) 1962; 196 Stoeckenius (bib44) 1963; 17 Dourmashkin, Dougherty, Harris (bib14) 1962; 81 Schulman, Rideal (bib39) 1937; 122 Steiner, Holtzem (bib42) 1955; vol. 3 ed. by R. M. C. Dawson & D. N. Rhodes, in the press. Lucy, Glauert (bib30) 1964 Valentine, Horne (bib46) 1962 Bangham, A. D. … Home, R. W. (1964). In Dervichian (bib11) 1958 van Bruggen, Wiebenga, Gruber (bib47) 1960; 42 Dawson (bib10) 1958; 68 Fernández-Morán (bib15) 1962; 26 Home, Whittaker (bib24) 1962; 58 Schmitt, Bear (bib37) 1937; 9 Brenner, Home (bib8) 1959; 34 Fleischer, Brierley (bib18) 1961; 5 Palmer, Schmitt (bib34) 1941; 17 Sjöstrand (bib41) 1963; 9 Lucy, Glauert (bib29) 1964 Davson, Danielli (bib9) 1952 Revel, Ito, Fawcett (bib35) 1958; 4 Stoeckenius (bib43) 1962; 12 van Bruggen, Wiebenga, Gruber (bib48) 1962; 4 Dingle, Lucy (bib12) 1962; 84 Luzzati, Husson (bib31) 1962; 12 Haydon, Taylor (bib23) 1963; 4 Bear, Palmer, Schmitt (bib7) 1941; 17 Sjöstrand (bib40) 1963; 199 Schmitt (bib36) 1963; 7 Glauert, Dingle, Lucy (bib22) 1962; 196 Home, Wildy (bib25) 1961; 15 Franklin, Klug, Holmes (bib19) 1957 Geren, Schmitt (bib20) 1953; 24 Glauert, Daniel, Lucy, Dingle (bib21) 1963; 17 Kerridge, Home, Glauert (bib26) 1962; 4 Ansevin, Lauffer (bib2) 1963; 3 Schmitt, Bear, Clark (bib38) 1935; 82 Finean (bib16) 1960; 8 Bangham, Dingle, Lucy (bib3) 1964; 90 Markham, Frey, Hills (bib33) 1963; 20 Macfarlane (bib32) 1960; vol. II Abram, Koffler (bib1) 1963; 19 Lucy (bib27) 1964 Franklin (10.1016/S0022-2836(64)80121-2_bib19) 1957 Revel (10.1016/S0022-2836(64)80121-2_bib35) 1958; 4 Brenner (10.1016/S0022-2836(64)80121-2_bib8) 1959; 34 Schmitt (10.1016/S0022-2836(64)80121-2_bib37) 1937; 9 Luzzati (10.1016/S0022-2836(64)80121-2_bib31) 1962; 12 Steiner (10.1016/S0022-2836(64)80121-2_bib42) 1955; vol. 3 Schmitt (10.1016/S0022-2836(64)80121-2_bib38) 1935; 82 Glauert (10.1016/S0022-2836(64)80121-2_bib22) 1962; 196 Fleischer (10.1016/S0022-2836(64)80121-2_bib18) 1961; 5 10.1016/S0022-2836(64)80121-2_bib28 Dingle (10.1016/S0022-2836(64)80121-2_bib12) 1962; 84 Davson (10.1016/S0022-2836(64)80121-2_bib9) 1952 Barton (10.1016/S0022-2836(64)80121-2_bib6) 1962; 84 Fernández-Morán (10.1016/S0022-2836(64)80121-2_bib15) 1962; 26 Ansevin (10.1016/S0022-2836(64)80121-2_bib2) 1963; 3 Lucy (10.1016/S0022-2836(64)80121-2_bib29) 1964 Haydon (10.1016/S0022-2836(64)80121-2_bib23) 1963; 4 Stoeckenius (10.1016/S0022-2836(64)80121-2_bib45) 1960; 169 Geren (10.1016/S0022-2836(64)80121-2_bib20) 1953; 24 Finean (10.1016/S0022-2836(64)80121-2_bib16) 1960; 8 Macfarlane (10.1016/S0022-2836(64)80121-2_bib32) 1960; vol. II Dourmashkin (10.1016/S0022-2836(64)80121-2_bib13) 1962; 194 Schmitt (10.1016/S0022-2836(64)80121-2_bib36) 1963; 7 Stoeckenius (10.1016/S0022-2836(64)80121-2_bib43) 1962; 12 van Bruggen (10.1016/S0022-2836(64)80121-2_bib47) 1960; 42 Abram (10.1016/S0022-2836(64)80121-2_bib1) 1963; 19 Home (10.1016/S0022-2836(64)80121-2_bib25) 1961; 15 Lucy (10.1016/S0022-2836(64)80121-2_bib30) 1964 Bangham (10.1016/S0022-2836(64)80121-2_bib3) 1964; 90 Valentine (10.1016/S0022-2836(64)80121-2_bib46) 1962 Sjöstrand (10.1016/S0022-2836(64)80121-2_bib41) 1963; 9 Dawson (10.1016/S0022-2836(64)80121-2_bib10) 1958; 68 Bangham (10.1016/S0022-2836(64)80121-2_bib4) 1962; 196 Finean (10.1016/S0022-2836(64)80121-2_bib17) 1963; 197 Home (10.1016/S0022-2836(64)80121-2_bib24) 1962; 58 Bear (10.1016/S0022-2836(64)80121-2_bib7) 1941; 17 Kerridge (10.1016/S0022-2836(64)80121-2_bib26) 1962; 4 van Bruggen (10.1016/S0022-2836(64)80121-2_bib48) 1962; 4 Lucy (10.1016/S0022-2836(64)80121-2_bib27) 1964 Glauert (10.1016/S0022-2836(64)80121-2_bib21) 1963; 17 Dourmashkin (10.1016/S0022-2836(64)80121-2_bib14) 1962; 81 Schulman (10.1016/S0022-2836(64)80121-2_bib39) 1937; 122 Markham (10.1016/S0022-2836(64)80121-2_bib33) 1963; 20 Palmer (10.1016/S0022-2836(64)80121-2_bib34) 1941; 17 Stoeckenius (10.1016/S0022-2836(64)80121-2_bib44) 1963; 17 10.1016/S0022-2836(64)80121-2_bib5 Dervichian (10.1016/S0022-2836(64)80121-2_bib11) 1958 Sjöstrand (10.1016/S0022-2836(64)80121-2_bib40) 1963; 199 |
References_xml | – start-page: 70 year: 1958 ident: bib11 publication-title: Surface Phenomena in Chemistry and Biology contributor: fullname: Dervichian – volume: 82 start-page: 44 year: 1935 ident: bib38 publication-title: Science contributor: fullname: Clark – volume: 90 start-page: 133 year: 1964 ident: bib3 publication-title: Biochem. J. contributor: fullname: Lucy – volume: 4 start-page: 1 year: 1962 ident: bib48 publication-title: J. Mol. Biol. contributor: fullname: Gruber – volume: 196 start-page: 952 year: 1962 ident: bib4 publication-title: Nature contributor: fullname: Home – volume: 15 start-page: 348 year: 1961 ident: bib25 publication-title: Virology contributor: fullname: Wildy – volume: 17 start-page: 443 year: 1963 ident: bib44 publication-title: J. Cell Biol. contributor: fullname: Stoeckenius – volume: 26 start-page: 1039 year: 1962 ident: bib15 publication-title: Circulation contributor: fullname: Fernández-Morán – volume: 5 start-page: 367 year: 1961 ident: bib18 publication-title: Biochim. Biophys. Res. Comm. contributor: fullname: Brierley – volume: 42 start-page: 171 year: 1960 ident: bib47 publication-title: Biochim. biophys. Acta contributor: fullname: Gruber – volume: vol. II start-page: 137 year: 1960 ident: bib32 publication-title: The Plasma Proteins contributor: fullname: Macfarlane – year: 1964 ident: bib29 publication-title: Symposium on Electron Microscopy contributor: fullname: Glauert – volume: 58 start-page: 1 year: 1962 ident: bib24 publication-title: Z. Zellforsch. contributor: fullname: Whittaker – volume: 24 start-page: 1421 year: 1953 ident: bib20 publication-title: J. Appt. Phys. contributor: fullname: Schmitt – volume: 194 start-page: 1116 year: 1962 ident: bib13 publication-title: Nature contributor: fullname: Harris – volume: 7 start-page: 546 year: 1963 ident: bib36 publication-title: Develop. Biol. contributor: fullname: Schmitt – volume: 81 start-page: 215 year: 1962 ident: bib14 publication-title: J. R. Mic. Soc. contributor: fullname: Harris – volume: 4 start-page: 281 year: 1963 ident: bib23 publication-title: J. Theoret. Biol. contributor: fullname: Taylor – volume: 196 start-page: 953 year: 1962 ident: bib22 publication-title: Nature contributor: fullname: Lucy – start-page: 39 year: 1957 ident: bib19 publication-title: The Nature of Viruses contributor: fullname: Holmes – volume: 4 start-page: 495 year: 1958 ident: bib35 publication-title: J. Biophys. Biochem. Cytol. contributor: fullname: Fawcett – volume: 17 start-page: 385 year: 1941 ident: bib34 publication-title: J. Cell. Comp. Physiol. contributor: fullname: Schmitt – volume: 12 start-page: 207 year: 1962 ident: bib31 publication-title: J. Cell. Biol. contributor: fullname: Husson – volume: 3 start-page: 239 year: 1963 ident: bib2 publication-title: Biophys. J. contributor: fullname: Lauffer – volume: 17 start-page: 111 year: 1963 ident: bib21 publication-title: J. Cell Biol. contributor: fullname: Dingle – volume: 197 start-page: 1326 year: 1963 ident: bib17 publication-title: Nature contributor: fullname: Rumsby – start-page: 293 year: 1962 ident: bib46 publication-title: The Interpretation of Ultrastructure contributor: fullname: Horne – volume: 9 start-page: 340 year: 1963 ident: bib41 publication-title: J. Ultrastructure Res. contributor: fullname: Sjöstrand – volume: 8 start-page: 13 year: 1960 ident: bib16 publication-title: J. Biophys. Biochem. Cytol. contributor: fullname: Finean – volume: 20 start-page: 88 year: 1963 ident: bib33 publication-title: Virology contributor: fullname: Hills – year: 1952 ident: bib9 publication-title: The Permeability of Natural Membranes contributor: fullname: Danielli – year: 1964 ident: bib30 publication-title: J. Gen. Microbiol contributor: fullname: Glauert – volume: 122 start-page: 29 year: 1937 ident: bib39 publication-title: Proc. Boy. Soc. B contributor: fullname: Rideal – volume: 17 start-page: 355 year: 1941 ident: bib7 publication-title: J. Cell. Comp. Physiol. contributor: fullname: Schmitt – volume: 34 start-page: 103 year: 1959 ident: bib8 publication-title: Biochim. biophys. Acta contributor: fullname: Home – volume: vol. 3 start-page: 58 year: 1955 ident: bib42 publication-title: Moderne Methoden der Pflanzenanalyse contributor: fullname: Holtzem – volume: 84 year: 1962 ident: bib6 publication-title: Biochem. J. contributor: fullname: Glover – volume: 199 start-page: 1262 year: 1963 ident: bib40 publication-title: Nature contributor: fullname: Sjöstrand – volume: 4 start-page: 227 year: 1962 ident: bib26 publication-title: J. Mol. Biol. contributor: fullname: Glauert – volume: 169 start-page: 170 year: 1960 ident: bib45 publication-title: Kolloid Z. contributor: fullname: Prince – volume: 68 start-page: 352 year: 1958 ident: bib10 publication-title: Biochem. J. contributor: fullname: Dawson – volume: 12 start-page: 221 year: 1962 ident: bib43 publication-title: J. Cell Biol contributor: fullname: Stoeckenius – volume: 19 start-page: 3A year: 1963 ident: bib1 publication-title: J. Cell Biol. contributor: fullname: Koffler – volume: 84 start-page: 611 year: 1962 ident: bib12 publication-title: Biochem. J. contributor: fullname: Lucy – year: 1964 ident: bib27 publication-title: Symposium on Metabolic Control Mechanisms. Nat. Cancer Inst. contributor: fullname: Lucy – volume: 9 start-page: 261 year: 1937 ident: bib37 publication-title: J. Cell. Comp. Physiol. contributor: fullname: Bear – volume: 15 start-page: 348 year: 1961 ident: 10.1016/S0022-2836(64)80121-2_bib25 publication-title: Virology doi: 10.1016/0042-6822(61)90366-X contributor: fullname: Home – volume: 9 start-page: 261 year: 1937 ident: 10.1016/S0022-2836(64)80121-2_bib37 publication-title: J. Cell. Comp. Physiol. doi: 10.1002/jcp.1030090209 contributor: fullname: Schmitt – start-page: 293 year: 1962 ident: 10.1016/S0022-2836(64)80121-2_bib46 contributor: fullname: Valentine – volume: 81 start-page: 215 year: 1962 ident: 10.1016/S0022-2836(64)80121-2_bib14 publication-title: J. R. Mic. Soc. doi: 10.1111/j.1365-2818.1963.tb02095.x contributor: fullname: Dourmashkin – ident: 10.1016/S0022-2836(64)80121-2_bib28 – volume: vol. II start-page: 137 year: 1960 ident: 10.1016/S0022-2836(64)80121-2_bib32 contributor: fullname: Macfarlane – volume: 4 start-page: 495 year: 1958 ident: 10.1016/S0022-2836(64)80121-2_bib35 publication-title: J. Biophys. Biochem. Cytol. doi: 10.1083/jcb.4.4.495 contributor: fullname: Revel – volume: 20 start-page: 88 year: 1963 ident: 10.1016/S0022-2836(64)80121-2_bib33 publication-title: Virology doi: 10.1016/0042-6822(63)90143-0 contributor: fullname: Markham – volume: 82 start-page: 44 year: 1935 ident: 10.1016/S0022-2836(64)80121-2_bib38 publication-title: Science doi: 10.1126/science.82.2115.44 contributor: fullname: Schmitt – start-page: 70 year: 1958 ident: 10.1016/S0022-2836(64)80121-2_bib11 contributor: fullname: Dervichian – volume: 12 start-page: 221 year: 1962 ident: 10.1016/S0022-2836(64)80121-2_bib43 publication-title: J. Cell Biol doi: 10.1083/jcb.12.2.221 contributor: fullname: Stoeckenius – volume: 197 start-page: 1326 year: 1963 ident: 10.1016/S0022-2836(64)80121-2_bib17 publication-title: Nature doi: 10.1038/1971326a0 contributor: fullname: Finean – volume: 7 start-page: 546 year: 1963 ident: 10.1016/S0022-2836(64)80121-2_bib36 publication-title: Develop. Biol. doi: 10.1016/0012-1606(63)90141-6 contributor: fullname: Schmitt – volume: vol. 3 start-page: 58 year: 1955 ident: 10.1016/S0022-2836(64)80121-2_bib42 contributor: fullname: Steiner – year: 1964 ident: 10.1016/S0022-2836(64)80121-2_bib27 contributor: fullname: Lucy – volume: 42 start-page: 171 year: 1960 ident: 10.1016/S0022-2836(64)80121-2_bib47 publication-title: Biochim. biophys. Acta doi: 10.1016/0006-3002(60)90771-X contributor: fullname: van Bruggen – year: 1964 ident: 10.1016/S0022-2836(64)80121-2_bib29 contributor: fullname: Lucy – volume: 17 start-page: 111 year: 1963 ident: 10.1016/S0022-2836(64)80121-2_bib21 publication-title: J. Cell Biol. doi: 10.1083/jcb.17.1.111 contributor: fullname: Glauert – start-page: 39 year: 1957 ident: 10.1016/S0022-2836(64)80121-2_bib19 contributor: fullname: Franklin – volume: 4 start-page: 281 year: 1963 ident: 10.1016/S0022-2836(64)80121-2_bib23 publication-title: J. Theoret. Biol. doi: 10.1016/0022-5193(63)90007-9 contributor: fullname: Haydon – volume: 169 start-page: 170 year: 1960 ident: 10.1016/S0022-2836(64)80121-2_bib45 publication-title: Kolloid Z. doi: 10.1007/BF01502567 contributor: fullname: Stoeckenius – volume: 9 start-page: 340 year: 1963 ident: 10.1016/S0022-2836(64)80121-2_bib41 publication-title: J. Ultrastructure Res. doi: 10.1016/S0022-5320(63)80011-8 contributor: fullname: Sjöstrand – volume: 17 start-page: 443 year: 1963 ident: 10.1016/S0022-2836(64)80121-2_bib44 publication-title: J. Cell Biol. doi: 10.1083/jcb.17.2.443 contributor: fullname: Stoeckenius – year: 1964 ident: 10.1016/S0022-2836(64)80121-2_bib30 publication-title: J. Gen. Microbiol contributor: fullname: Lucy – volume: 8 start-page: 13 year: 1960 ident: 10.1016/S0022-2836(64)80121-2_bib16 publication-title: J. Biophys. Biochem. Cytol. doi: 10.1083/jcb.8.1.13 contributor: fullname: Finean – volume: 17 start-page: 385 year: 1941 ident: 10.1016/S0022-2836(64)80121-2_bib34 publication-title: J. Cell. Comp. Physiol. doi: 10.1002/jcp.1030170313 contributor: fullname: Palmer – volume: 84 year: 1962 ident: 10.1016/S0022-2836(64)80121-2_bib6 publication-title: Biochem. J. contributor: fullname: Barton – volume: 19 start-page: 3A year: 1963 ident: 10.1016/S0022-2836(64)80121-2_bib1 publication-title: J. Cell Biol. contributor: fullname: Abram – volume: 68 start-page: 352 year: 1958 ident: 10.1016/S0022-2836(64)80121-2_bib10 publication-title: Biochem. J. doi: 10.1042/bj0680352 contributor: fullname: Dawson – volume: 58 start-page: 1 year: 1962 ident: 10.1016/S0022-2836(64)80121-2_bib24 publication-title: Z. Zellforsch. doi: 10.1007/BF00406937 contributor: fullname: Home – volume: 199 start-page: 1262 year: 1963 ident: 10.1016/S0022-2836(64)80121-2_bib40 publication-title: Nature doi: 10.1038/1991262a0 contributor: fullname: Sjöstrand – volume: 4 start-page: 227 year: 1962 ident: 10.1016/S0022-2836(64)80121-2_bib26 publication-title: J. Mol. Biol. doi: 10.1016/S0022-2836(62)80001-1 contributor: fullname: Kerridge – volume: 5 start-page: 367 year: 1961 ident: 10.1016/S0022-2836(64)80121-2_bib18 publication-title: Biochim. Biophys. Res. Comm. doi: 10.1016/0006-291X(61)90042-0 contributor: fullname: Fleischer – year: 1952 ident: 10.1016/S0022-2836(64)80121-2_bib9 contributor: fullname: Davson – volume: 4 start-page: 1 year: 1962 ident: 10.1016/S0022-2836(64)80121-2_bib48 publication-title: J. Mol. Biol. doi: 10.1016/S0022-2836(62)80110-7 contributor: fullname: van Bruggen – volume: 3 start-page: 239 year: 1963 ident: 10.1016/S0022-2836(64)80121-2_bib2 publication-title: Biophys. J. doi: 10.1016/S0006-3495(63)86818-6 contributor: fullname: Ansevin – volume: 17 start-page: 355 year: 1941 ident: 10.1016/S0022-2836(64)80121-2_bib7 publication-title: J. Cell. Comp. Physiol. doi: 10.1002/jcp.1030170311 contributor: fullname: Bear – volume: 34 start-page: 103 year: 1959 ident: 10.1016/S0022-2836(64)80121-2_bib8 publication-title: Biochim. biophys. Acta doi: 10.1016/0006-3002(59)90237-9 contributor: fullname: Brenner – volume: 26 start-page: 1039 year: 1962 ident: 10.1016/S0022-2836(64)80121-2_bib15 publication-title: Circulation doi: 10.1161/01.CIR.26.5.1039 contributor: fullname: Fernández-Morán – volume: 24 start-page: 1421 year: 1953 ident: 10.1016/S0022-2836(64)80121-2_bib20 publication-title: J. Appt. Phys. contributor: fullname: Geren – volume: 122 start-page: 29 year: 1937 ident: 10.1016/S0022-2836(64)80121-2_bib39 publication-title: Proc. Boy. Soc. B doi: 10.1098/rspb.1937.0008 contributor: fullname: Schulman – volume: 194 start-page: 1116 year: 1962 ident: 10.1016/S0022-2836(64)80121-2_bib13 publication-title: Nature doi: 10.1038/1941116a0 contributor: fullname: Dourmashkin – volume: 196 start-page: 952 year: 1962 ident: 10.1016/S0022-2836(64)80121-2_bib4 publication-title: Nature doi: 10.1038/196952a0 contributor: fullname: Bangham – ident: 10.1016/S0022-2836(64)80121-2_bib5 – volume: 84 start-page: 611 year: 1962 ident: 10.1016/S0022-2836(64)80121-2_bib12 publication-title: Biochem. J. doi: 10.1042/bj0840611 contributor: fullname: Dingle – volume: 12 start-page: 207 year: 1962 ident: 10.1016/S0022-2836(64)80121-2_bib31 publication-title: J. Cell. Biol. doi: 10.1083/jcb.12.2.207 contributor: fullname: Luzzati – volume: 90 start-page: 133 year: 1964 ident: 10.1016/S0022-2836(64)80121-2_bib3 publication-title: Biochem. J. doi: 10.1042/bj0900133 contributor: fullname: Bangham – volume: 196 start-page: 953 year: 1962 ident: 10.1016/S0022-2836(64)80121-2_bib22 publication-title: Nature doi: 10.1038/196953a0 contributor: fullname: Glauert |
SSID | ssj0005348 |
Score | 1.2946482 |
Snippet | Negatively-stained preparations of various mixtures of lecithin, cholesterol and saponin have been investigated by electron microscopy. Lamellar, tubular,... |
SourceID | proquest crossref pubmed elsevier |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 727,IN12 |
SubjectTerms | Cholesterol Electrons Lecithins Lipids Macromolecular Substances Micelles Microscopy Microscopy, Electron Old Medline Phosphatidylcholines Saponins |
Title | Structure and assembly of macromolecular lipid complexes composed of globular micelles |
URI | https://dx.doi.org/10.1016/S0022-2836(64)80121-2 https://www.ncbi.nlm.nih.gov/pubmed/14187398 https://search.proquest.com/docview/83577996 |
Volume | 8 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb5wwELbaVFV7qdL0tW3T-tBKrSISHgbMkRCyaQUlWpZqc7IMi2_ZRO3m0P76jo0NJOmqjwtCYAOa79P4s_HMIPSOEOFEnDQWj4RrEanhah7UFrhCvxGc8lbl6c6_BCcV-bzwF6aWvI4uWdf7zc_fxpX8D6pwDXCVUbL_gGz_ULgA54AvHAFhOP4VxuV8ViVq34JMEhWXZZofZmdyI08eJ7MiL7I0qbJ4Bi7q9NPRXlLkp1m6SEt1VpTpkWw6zYpD1QgASbNMq8PbevXcFNLd04mb-r08VXKmyDCsi06zuEpn887x5MPKgszLNVpZGHb6g_wIxt6Sjrxd2IX13_LC3YJA2fcHrRyQ924kR0Md7ThC5_JcweMQh4ZeV5L6Rgpsc-suuueGkS_n2NPFaCePR6hJCi9fNwRqHQzf8CEgH_X7ZaJY_cRNamTTbEOpjvk2eqTNj-MO-8foTrvaQfe7AqI_dtCDxNTre4K-9mzAwAZs2ICLY3ydDVixAfdswIYNsqlhAzZseIqq43SenFi6aobVkChcWw5vWhI2wpZ5kygMX4IuKYjexoPZpwDB7orIqVuZSy4CZ8xhlHHsOhL-0oVxz3e9Z2hrdbFqXyC8DLnnCU_YTevLygWcQmfPpXZr1y73ognaN9Zjl11yFDbsGgTLM2l5FhCmLM_cCaLGxkwrvE65MaDOn7q-NZgwMKz8rcVX7cXVdwZziDCEafsEPe-gGr5Fo_xy451X6OHA_Ndoa_3tqt0Flbmu3yiO_QLrRmCt |
link.rule.ids | 315,786,790,27957,27958 |
linkProvider | Geneva Foundation for Medical Education and Research |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=STRUCTURE+AND+ASSEMBLY+OF+MACROMOLECULAR+LIPID+COMPLEXES+COMPOSED+OF+GLOBULAR+MICELLES&rft.jtitle=Journal+of+molecular+biology&rft.au=LUCY%2C+J+A&rft.au=GLAUERT%2C+A+M&rft.date=1964-01-01&rft.issn=0022-2836&rft.volume=8&rft.spage=727&rft_id=info:doi/10.1016%2FS0022-2836%2864%2980121-2&rft_id=info%3Apmid%2F14187398&rft.externalDocID=14187398 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0022-2836&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0022-2836&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0022-2836&client=summon |