In vitro differentiation of neural progenitor cells from prenatal rat brain: Common cell surface glycoprotein on three glial cell subsets

• Published in: Journal of neuroscience research Vol. 48; no. 2; pp. 95 - 111
• Main Authors: Blass-Kampmann, Sabine, Kindler-Röhrborn, Andrea, Deissler, Helmut, D'Urso, Donatella, Rajewsky, Manfred F.
• Format: Journal Article
• Language: English
• Published: New York John Wiley & Sons, Inc 15.04.1997
• Subjects: Animals; Antibodies, Monoclonal; Antigens, CD - analysis; Antigens, CD - immunology; astrocytes; Astrocytes - chemistry; Astrocytes - cytology; Blotting, Western; Brain - cytology; Brain - embryology; Brain - growth & development; Brain Chemistry - physiology; brain development; Cell Differentiation - physiology; Cells, Cultured; Cross Reactions; Cytokine Receptor gp130; Ependyma - chemistry; Ependyma - cytology; ependymal cells; Female; Fetus - cytology; Flow Cytometry; Fluorescent Antibody Technique; Humans; in vitro differentiation; Male; Membrane Glycoproteins - analysis; Membrane Glycoproteins - immunology; microglia; Microglia - chemistry; Microglia - cytology; Neurons - chemistry; Neurons - cytology; Pregnancy; radial glia; Rats; Rats, Inbred Strains; Signal Transduction - physiology; Stem Cells - chemistry; Stem Cells - cytology

Glial progenitor cell differentiation and cell lineage relationships during brain development are complex hierarchical processes depending on genetic programming, cell‐cell interactions, and microenvironmental factors. The identification of precursor cell‐specific antigens provides a tool for the st...