Pharmacokinetics of lenalidomide in subjects with various degrees of renal impairment and in subjects on hemodialysis - Chen, Nianhang; Lau, Henry; Kong, Linghui; Kumar, Gondi; Zeldis, Jerome B; Knight, Robert; Laskin, Oscar L (Journal of clinical pharmacology, 2007)
Keywords: Administration, Oral; Adult; Aged; Antineoplastic Agents - administration & dosage; Antineoplastic Agents - pharmacokinetics; Area Under Curve; Disease Progression; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Kidney - metabolism; Kidney - pathology; Kidney - physiopathology; Kidney Failure, Chronic - metabolism; Kidney Failure, Chronic - physiopathology; Kidney Failure, Chronic - therapy; Male; Metabolic Clearance Rate; Middle Aged; Renal Dialysis; Severity of Illness Index; Stereoisomerism; Tandem Mass Spectrometry; Thalidomide - analogs & derivatives; Thalidomide - chemistry; Thalidomide - pharmacokinetics