Validation of a Host Response Assay, SeptiCyte LAB, for Discriminating Sepsis from Systemic Inflammatory Response Syndrome in the ICU - Miller, Russell R.; Lopansri, Bert K.; Burke, John P.; Levy, Mitchell; Opal, Steven; Rothman, Richard E.; D’Alessio, Franco R.; Sidhaye, Venkataramana K.; Aggarwal, Neil R.; Balk, Robert; Greenberg, Jared A.; Yoder, Mark; et al. (American journal of respiratory and critical care medicine, 2018)
Keywords: Adult; Aged; Antibiotics; Bacterial infections; Biomarkers; Clinical trials; Cohort Studies; Consortia; Critical Care - methods; Critical Illness; Diagnosis, Differential; Ethics; FDA approval; Female; Gene expression; Humans; Infections; Inflammation; Intensive Care Units; Laboratories; Male; Middle Aged; Netherlands; Original; Pneumonia; Prospective Studies; Retrospective Studies; ROC Curve; Sensitivity and Specificity; Sepsis; Sepsis - blood; Sepsis - diagnosis; Serum Bactericidal Test - methods; Systemic Inflammatory Response Syndrome - blood; Systemic Inflammatory Response Syndrome - diagnosis; United States; Ventilators; United States; Netherlands; United States--US; classifier; infection; inflammation; RT-qPCR; sepsis