Acetyl-L-Carnitine downregulates invasion (CXCR4/CXCL12, MMP-9) and angiogenesis (VEGF, CXCL8) pathways in prostate cancer cells: rationale for prevention and interception strategies - Baci, Denisa; Bruno, Antonino; Cascini, Caterina; Gallazzi, Matteo; Mortara, Lorenzo; Sessa, Fausto; Pelosi, Giuseppe; Albini, Adriana; Noonan, Douglas M. (Journal of experimental & clinical cancer research, 2019)
Keywords: Acetylcarnitine - pharmacology; Analysis; Angiogenesis; Angiogenesis Inducing Agents - metabolism; Angioprevention; Animals; Anti-inflammatory agents; Antigens; Apoptosis - drug effects; Aspirin; Cancer cells; Cancer prevention; Carnitine; Cell cycle; Chemoprevention; Death; Development and progression; Dietary supplements; Down-Regulation; Endothelial growth factors; Endothelium; Health aspects; Human Umbilical Vein Endothelial Cells; Humans; Hyperplasia; Inflammation; Levocarnitine; Male; Mass spectrometry; Medical equipment industry; Mice; Mice, Nude; PC-3 Cells; Prevention; Prostate cancer; Prostatic hyperplasia; Prostatic Neoplasms - drug therapy; Prostatic Neoplasms - genetics; Prostatic Neoplasms - metabolism; Prostatic Neoplasms - pathology; Spectroscopy; Tumors; Xenograft Model Antitumor Assays; United States; Angiogenesis; Chemoprevention; Inflammation; Interception; Prostate cancer; Angioprevention; Carnitine