Significant association between rs28362491 polymorphism in NF-κB1 gene and coronary artery disease: a meta-analysis

• Published in: BMC cardiovascular disorders Vol. 20; no. 1; p. 278
• Main Authors: Wang, Yanwei, Wu, Bianwen, Zhang, Muqing, Miao, Huawei, Sun, Jiaan
• Format: Journal Article
• Language: English
• Published: England BioMed Central 08.06.2020; BMC
• Subjects: Alleles; Angina pectoris; Bias; Cardiovascular disease; Case-Control Studies; Coronary artery; Coronary artery disease; Coronary Artery Disease - diagnostic imaging; Coronary Artery Disease - genetics; Coronary vessels; Ethnicity; Female; Gender; Gene polymorphism; Genes; Genetic Association Studies; Genetic Predisposition to Disease; Heart attacks; Heart Disease Risk Factors; Heart diseases; Humans; Male; Meta-analysis; NF-kappa B p50 Subunit - genetics; NF-κB1; Polymorphism; Polymorphism, Single Nucleotide; Quality; Risk Assessment; Rs28362491; Sensitivity analysis; Studies; NF-κB1; Coronary artery disease; Rs28362491; Meta-analysis; Polymorphism

The association of rs28362491 polymorphism in NF-κB1 gene and coronary artery disease (CAD) risk was reported in several studies with inconsistent outcomes. This study aimed to comprehensively collect and synthesize the existing evidence to appraise whether rs28362491 was correlated to CAD susceptib...