Hindlimb unloading alters ligament healing

• Published in: Journal of applied physiology (1985) Vol. 94; no. 1; pp. 314 - 324
• Main Authors: Provenzano, Paolo P, Martinez, Daniel A, Grindeland, Richard E, Dwyer, Kelley W, Turner, Joanne, Vailas, Arthur C, Vanderby, Ray, Jr
• Format: Journal Article
• Language: English
• Published: Legacy CDMS Am Physiological Soc 01.01.2003; American Physiological Society
• Subjects: Aerospace Medicine; Anatomy & physiology; Animals; Biological and medical sciences; Biomechanical Phenomena; Bone Density; Cicatrix - pathology; Collagen - ultrastructure; Elasticity; Extracellular Matrix - metabolism; Extracellular Matrix - pathology; Femur - physiopathology; Fundamental and applied biological sciences. Psychology; Hindlimb Suspension; Ligaments; Ligaments - physiopathology; Ligaments - ultrastructure; Male; Microscopy, Electron, Scanning; Motor Activity - physiology; Muscle, Skeletal - pathology; Rats; Rats, Sprague-Dawley; Rodents; Space life sciences; Striated muscle. Tendons; Tensile Strength; Vertebrates: osteoarticular system, musculoskeletal system; Wound Healing; Non-Nasa Center; Nasa Discipline Musculoskeletal; Ligament; Rat; hindlimb suspension; Glycoprotein; Rodentia; Lower limb; Mechanical properties; Suspension; bone; Structure function relationship; Osteoarticular system; Biomechanics; Vertebrata; Mammalia; Collagen; muscle; Inhibition; disuse; Cicatrization; NASA Discipline Musculoskeletal; Non-NASA Center

1  Orthopedic Research Laboratories, Department of Orthopedics and Rehabilitation and Department of Biomedical Engineering, University of Wisconsin, Madison, Wisconsin 53792-3228; 2  Connective Tissue Physiology Laboratory, Department of Biology and Biochemistry, University of Houston, Houston, Texa...