Design, synthesis, and biological evaluation of chalcones for anticancer properties targeting glycogen synthase kinase 3 beta - Ahn, Seunghyun; Truong, Vi Nguyen-Phuong; Kim, Beomsoo; Yoo, Miri; Lim, Yoongho; Cho, Somi Kim; Koh, Dongsoo (Applied biological chemistry, 2022)
Keywords: Anticancer properties; antineoplastic activity; Antitumor activity; Apoptosis; Applied Microbiology; Assaying; Binding; biological assessment; Biological Techniques; Bioorganic Chemistry; Cancer; Cell viability; chalcone; Chemistry; Chemistry and Materials Science; computer simulation; dose response; Drug development; Glycogen; Glycogen synthase kinase 3; Glycogens; Kinases; Mass spectrometry; Mass spectroscopy; Mesenchyme; NMR; Nuclear magnetic resonance; nuclear magnetic resonance spectroscopy; Survival; tau-protein kinase; Western blotting; Wound healing; 농학; GSK3β; In silico docking; Colonogenic; Chalcone; MCF-7SC