Matrix vesicle biomimetics harboring Annexin A5 and alkaline phosphatase bind to the native collagen matrix produced by mineralizing vascular smooth muscle cells - Bolean, Maytê; Izzi, Benedetta; van kerckhoven, Soetkin; Bottini, Massimo; Ramos, Ana Paula; Millán, José Luis; Hoylaerts, Marc F.; Ciancaglini, Pietro (Biochimica et biophysica acta. General subjects, 2020)
Keywords: Alkaline phosphatase; Annexin A5; Annexin A5 - metabolism; Binding Sites; Biomimetic Materials - metabolism; biomimetics; calcification; cardiovascular diseases; Carrier Proteins - metabolism; cartilage; Cell Differentiation; Collagen; Collagen - metabolism; extracellular matrix; Extracellular Matrix - metabolism; Humans; lipids; Matrix vesicles; mineralization; Muscle, Smooth, Vascular - cytology; Muscle, Smooth, Vascular - metabolism; myocytes; Phosphatidylserine; Proteolipids - metabolism; Proteoliposomes; smooth muscle; synergism; therapeutics; Alkaline phosphatase; VSMCs; Matrix vesicles; PPi; MVs; ECM; TNAP; Proteoliposomes; DPPS; Collagen; Annexin A5; AnxA5; HA; Pi; Phosphatidylserine; DPPC