A Comprehensive Comparison between Primary Liver Cancer and Liver Metastases through scRNA-Seq Data Analysis

• Published in: Metabolites Vol. 14; no. 2; p. 90
• Main Authors: Hao, Shuang, Chen, Liqun, Du, Wenhui, Sun, Huiyan
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.01.2024
• Subjects: Analysis; Annotations; Breast cancer; Cancer therapies; Causes of; Cell growth; Cell interactions; Cell proliferation; Clustering; Communication; Comparative analysis; Complications and side effects; comprehensive comparison; Cytotoxicity; Datasets; Diagnosis; Energy metabolism; Gene expression; Genomes; Health aspects; Hepatocytes; Liver cancer; Lymphocytes T; Metastases; Metastasis; metastatic liver cancer; Monocytes; RNA sequencing; single-cell RNA-Seq; Tumors; China; comprehensive comparison; single-cell RNA-Seq; cell proliferation; metastatic liver cancer

Metastasis is one of the leading causes of cancer-related deaths. A comprehensive comparison of the differences between primary and metastatic cancers within the same organ can aid in understanding the growth mechanisms of cancer cells at metastatic sites, thereby helping to develop more effective t...