Inhalable antibiotic resistomes emitted from hospitals: metagenomic insights into bacterial hosts, clinical relevance, and environmental risks

• Published in: Microbiome Vol. 10; no. 1; pp. 19 - 16
• Main Authors: Wu, Dong, Jin, Ling, Xie, Jiawen, Liu, Hang, Zhao, Jue, Ye, Dan, Li, Xiang-dong
• Format: Journal Article
• Language: English
• Published: England BioMed Central 27.01.2022; BMC
• Subjects: Abundance; Aluminum; AMR risk; Anti-Bacterial Agents - pharmacology; Antibiotic resistance; Antibiotic resistome; Antibiotics; Antimicrobial resistance; ARG-hosting bacteria; Bacteria; Bacteria - genetics; Commensals; Drinking water; Genes, Bacterial; Genetic testing; Genomes; Health risk assessment; Health risks; Healthcare-associated infection; Horizontal transfer; Hospital PM2.5; Hospitals; Humans; Infections; Inhalation; Metagenome - genetics; Metagenomics; Particulate matter; Pathogens; Pulmonology; RNA, Ribosomal, 16S - genetics; rRNA 16S; Summer; Taxonomy; Ventilators; Winter; β-Lactam antibiotics; United States > US; China; Hospital PM2.5; AMR risk; Healthcare-associated infection; ARG-hosting bacteria; Antibiotic resistome

Threats of antimicrobial resistance (AMR) to human health are on the rise worldwide. Airborne fine particulate matter (PM ), especially those emitted from hospitals, could serve as a substantial yet lesser-known environmental medium of inhalable antibiotic resistomes. A genome-centric understanding...