Junctional adhesion molecule-like protein promotes tumor progression via the Wnt/β-catenin signaling pathway in lung adenocarcinoma

• Published in: Journal of translational medicine Vol. 20; no. 1; pp. 260 - 17
• Main Authors: Wu, Qian, Li, Rui, Wang, Qing-Xiang, Zhang, Meng-Yu, Liu, Ting-Ting, Qu, Yi-Qing
• Format: Journal Article
• Language: English
• Published: England BioMed Central 07.06.2022; BMC
• Subjects: Adenocarcinoma; Antibodies; Antigens; Apoptosis; Cell cycle; Cell migration; Cell proliferation; Flow cytometry; G1 phase; Gastric cancer; Human subjects; Immunohistochemistry; Invasion; Junctional adhesion molecule-like protein; Lung adenocarcinoma; Lung cancer; Mesenchyme; Microscopy; Migration; Molecular modelling; Plasmids; Reagents; Signal transduction; siRNA; Software; Therapeutic targets; Transfection; Tumor progression; Tumorigenesis; Western blotting; Wnt protein; Wound healing; Xenografts; β-Catenin; China; Junctional adhesion molecule-like protein; Lung adenocarcinoma; Migration; Invasion; Tumor progression

Lung adenocarcinoma (LUAD) is a heavy social burden worldwide. Because the mechanisms involved in LUAD remain unclear, the prognosis of LUAD remains poor. Consequently, it is urgent to investigate the potential mechanisms of LUAD. Junctional adhesion molecule-like protein (JAML), is recognized as a...