Asteropsins B–D, sponge-derived knottins with potential utility as a novel scaffold for oral peptide drugs - Li, Huayue; Bowling, John J.; Su, Mingzhi; Hong, Jongki; Lee, Bong-Jin; Hamann, Mark T.; Jung, Jee H. (Biochimica et biophysica acta, 2014)
Keywords: Administration, Oral; Amino Acid Sequence; Animals; Asteropus sp; Calcium - metabolism; chymotrypsin; Cystine-Knot Miniproteins - chemistry; Drug Discovery; drugs; elastase; engineering; gastrointestinal system; humans; Knottin; Marine sponge; Models, Molecular; Molecular Sequence Data; NMR; nuclear magnetic resonance spectroscopy; Oral peptide drug delivery; pepsin; peptides; Porifera; Porifera - chemistry; Protein Stability; Protein Structure, Secondary; Protein Structure, Tertiary; Solution structure; trypsin; Marine sponge; NMR; Knottin; Asteropus sp; Oral peptide drug delivery; Solution structure