The novel inflammatory biomarker GlycA and triglyceride-rich lipoproteins are associated with the presence of subclinical myocardial dysfunction in subjects with type 1 diabetes mellitus

• Published in: Cardiovascular diabetology Vol. 21; no. 1; pp. 257 - 11
• Main Authors: Puig-Jové, Carlos, Julve, Josep, Castelblanco, Esmeralda, Julián, M Teresa, Amigó, Núria, Andersen, Henrik U, Ahluwalia, Tarunveer S, Rossing, Peter, Mauricio, Dídac, Jensen, Magnus T, Alonso, Núria
• Format: Journal Article
• Language: English
• Published: England BioMed Central 24.11.2022; BMC
• Subjects: Biochemistry; Biomarkers; Blood pressure; Cardiology; Cardiomyopathies; Cardiomyopathy; Cardiovascular disease; Cholesterol; Classification; Congestive heart failure; Coronary vessels; Creatinine; Diabetes; Diabetes mellitus (insulin dependent); Diabetes Mellitus, Type 1 - complications; Diabetes Mellitus, Type 1 - diagnosis; Diabetes Mellitus, Type 1 - epidemiology; Echocardiography; Ejection fraction; Enzymes; GlycA; Glycoproteins; Glycosylation; Heart; Heart failure; High density lipoprotein; Humans; Inflammation; Lipids; Lipoproteins; Lipoproteins (very low density); Mortality; Myocardial dysfunction; NMR; Nuclear magnetic resonance; Retinopathy; Spectrum analysis; Stroke Volume - physiology; Triglycerides; Type 1 diabetes; Ultrasonic imaging; Ventricle; Ventricular Dysfunction, Left - diagnostic imaging; Ventricular Dysfunction, Left - epidemiology; Ventricular Function, Left; Germany; Heart failure; GlycA; Lipoproteins; Type 1 diabetes; Myocardial dysfunction

Subjects with Type 1 diabetes mellitus (T1DM) have an increased incidence of heart failure (HF). Several pathophysiological mechanisms have been involved in its development. The aim of this study was to analyze the potential contribution of the advanced lipoprotein profile and plasma glycosylation (...