A Randomized Open label Phase-II Clinical Trial with or without Infusion of Plasma from Subjects after Convalescence of SARS-CoV-2 Infection in High-Risk Patients with Confirmed Severe SARS-CoV-2 Disease (RECOVER): A structured summary of a study protocol for a randomised controlled trial - Janssen, Maike; Schäkel, Ulrike; Djuka Fokou, Carine; Krisam, Johannes; Stermann, Jacek; Kriegsmann, Katharina; Haberbosch, Isabella; Novotny, Jan Philipp; Weber, Stefan; Vehreschild, Maria; Bornhäuser, Martin; Bullinger, Lars; et al. (Current controlled trials in cardiovascular medicine, 2020)
Keywords: Aged; Antibodies, Viral - blood; Betacoronavirus - immunology; Betacoronavirus - isolation & purification; Clinical Trials, Phase II as Topic; Consent; Convalescence; convalescent plasma; Coronavirus Infections - diagnosis; Coronavirus Infections - immunology; Coronavirus Infections - therapy; COVID-19; early application; Ethics; Female; high-risk patients with severe disease; Humans; Immunization, Passive - methods; Letter; Male; Middle Aged; Monitoring, Physiologic - methods; Multicenter Studies as Topic; Pandemics; Plasma - immunology; Pneumonia, Viral - diagnosis; Pneumonia, Viral - immunology; Pneumonia, Viral - therapy; protocol; Randomised controlled trial; Randomized Controlled Trials as Topic; Risk Adjustment; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Severity of Illness Index; Writing; COVID-19; protocol; high-risk patients with severe disease; early application; Randomised controlled trial; convalescent plasma