Cultivation-independent genomes greatly expand taxonomic-profiling capabilities of mOTUs across various environments

• Published in: Microbiome Vol. 10; no. 1; pp. 212 - 12
• Main Authors: Ruscheweyh, Hans-Joachim, Milanese, Alessio, Paoli, Lucas, Karcher, Nicolai, Clayssen, Quentin, Keller, Marisa Isabell, Wirbel, Jakob, Bork, Peer, Mende, Daniel R., Zeller, Georg, Sunagawa, Shinichi
• Format: Journal Article
• Language: English
• Published: England BioMed Central 05.12.2022; BMC
• Subjects: Animals; Benchmarking; Cattle; Comparative analysis; Datasets; Gastrointestinal tract; Genomes; Marker gene; Metagenome - genetics; Metagenome-assembled genome; Metagenomics; Microbial community; Microbiomes; Microbiota - genetics; Microorganisms; Relative abundance; RNA, Ribosomal, 16S - genetics; rRNA 16S; Software; Soil; Species; Swine; Taxonomic profiling; Taxonomy; Single-cell genome; Taxonomic profiling; Metagenomics; Metagenome-assembled genome; Reference genome; Benchmarking; Marker gene; Microbial community

Taxonomic profiling is a fundamental task in microbiome research that aims to detect and quantify the relative abundance of microorganisms in biological samples. Available methods using shotgun metagenomic data generally depend on the deposition of sequenced and taxonomically annotated genomes, usua...