Double-Blind, Randomized, Placebo-Controlled Phase III Clinical Trial to Evaluate the Efficacy and Safety of treating Healthcare Professionals with the Adsorbed COVID-19 (Inactivated) Vaccine Manufactured by Sinovac – PROFISCOV: A structured summary of a study protocol for a randomised controlled trial - Palacios, Ricardo; Patiño, Elizabeth González; de Oliveira Piorelli, Roberta; Conde, Monica Tilli Reis Pessoa; Batista, Ana Paula; Zeng, Gang; Xin, Qianqian; Kallas, Esper G.; Flores, Jorge; Ockenhouse, Christian F.; Gast, Christopher (Current controlled trials in cardiovascular medicine, 2020)
Keywords: Adolescent; Adult; Age groups; Aged; Betacoronavirus - genetics; Betacoronavirus - immunology; Brazil - epidemiology; Case-Control Studies; Clinical trials; Coronavirus Infections - epidemiology; Coronavirus Infections - immunology; Coronavirus Infections - prevention & control; Coronavirus Infections - virology; Coronaviruses; COVID-19; COVID-19 Vaccine; COVID-19 vaccines; Data Management; Double-Blind Method; Female; Health Personnel - statistics & numerical data; Humans; Immunization; Inactivated Vaccines; Incidence; Informed Consent - ethics; Injections, Intramuscular; Letter; Male; Medical personnel; Middle Aged; Pandemics - prevention & control; Phase III Clinical Trial; Placebos - administration & dosage; Pneumonia, Viral - epidemiology; Pneumonia, Viral - immunology; Pneumonia, Viral - prevention & control; Pneumonia, Viral - virology; protocol; Randomised controlled trial; Safety; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Therapies, Investigational - methods; Treatment Outcome; Vaccination - methods; Vaccines - administration & dosage; Vaccines - adverse effects; Vaccines - therapeutic use; Young Adult; Brazil; COVID-19; COVID-19 Vaccine; Phase III Clinical Trial; protocol; Randomised controlled trial; Brazil; Inactivated Vaccines