Using naso- and oro-intestinal catheters in physiological research for intestinal delivery and sampling in vivo: practical and technical aspects to be considered
Intestinal catheters have been used for decades in human nutrition, physiology, pharmacokinetics, and gut microbiome research, facilitating the delivery of compounds directly into the intestinal lumen or the aspiration of intestinal fluids in human subjects. Such research provides insights about (lo...
Saved in:
| Published in | The American journal of clinical nutrition Vol. 114; no. 3; pp. 843 - 861 |
|---|---|
| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
01.09.2021
American Society for Clinical Nutrition, Inc Oxford University Press |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Intestinal catheters have been used for decades in human nutrition, physiology, pharmacokinetics, and gut microbiome research, facilitating the delivery of compounds directly into the intestinal lumen or the aspiration of intestinal fluids in human subjects. Such research provides insights about (local) dynamic metabolic and other intestinal luminal processes, but working with catheters might pose challenges to biomedical researchers and clinicians. Here, we provide an overview of practical and technical aspects of applying naso- and oro-intestinal catheters for delivery of compounds and sampling luminal fluids from the jejunum, ileum, and colon in vivo. The recent literature was extensively reviewed, and combined with experiences and insights we gained through our own clinical trials. We included 60 studies that involved a total of 720 healthy subjects and 42 patients. Most of the studies investigated multiple intestinal regions (24 studies), followed by studies investigating only the jejunum (21 studies), ileum (13 studies), or colon (2 studies). The ileum and colon used to be relatively inaccessible regions in vivo. Custom-made state-of-the-art catheters are available with numerous options for the design, such as multiple lumina, side holes, and inflatable balloons for catheter progression or isolation of intestinal segments. These allow for multiple controlled sampling and compound delivery options in different intestinal regions. Intestinal catheters were often used for delivery (23 studies), sampling (10 studies), or both (27 studies). Sampling speed decreased with increasing distance from the sampling syringe to the specific intestinal segment (i.e., speed highest in duodenum, lowest in ileum/colon). No serious adverse events were reported in the literature, and a dropout rate of around 10% was found for these types of studies. This review is highly relevant for researchers who are active in various research areas and want to expand their research with the use of intestinal catheters in humans in vivo. |
|---|---|
| AbstractList | Intestinal catheters have been used for decades in human nutrition, physiology, pharmacokinetics, and gut microbiome research, facilitating the delivery of compounds directly into the intestinal lumen or the aspiration of intestinal fluids in human subjects. Such research provides insights about (local) dynamic metabolic and other intestinal luminal processes, but working with catheters might pose challenges to biomedical researchers and clinicians. Here, we provide an overview of practical and technical aspects of applying naso- and oro-intestinal catheters for delivery of compounds and sampling luminal fluids from the jejunum, ileum, and colon in vivo. The recent literature was extensively reviewed, and combined with experiences and insights we gained through our own clinical trials. We included 60 studies that involved a total of 720 healthy subjects and 42 patients. Most of the studies investigated multiple intestinal regions (24 studies), followed by studies investigating only the jejunum (21 studies), ileum (13 studies), or colon (2 studies). The ileum and colon used to be relatively inaccessible regions in vivo. Custom-made state-of-the-art catheters are available with numerous options for the design, such as multiple lumina, side holes, and inflatable balloons for catheter progression or isolation of intestinal segments. These allow for multiple controlled sampling and compound delivery options in different intestinal regions. Intestinal catheters were often used for delivery (23 studies), sampling (10 studies), or both (27 studies). Sampling speed decreased with increasing distance from the sampling syringe to the specific intestinal segment (i.e., speed highest in duodenum, lowest in ileum/colon). No serious adverse events were reported in the literature, and a dropout rate of around 10% was found for these types of studies. This review is highly relevant for researchers who are active in various research areas and want to expand their research with the use of intestinal catheters in humans in vivo. Intestinal catheters have been used for decades in human nutrition, physiology, pharmacokinetics, and gut microbiome research, facilitating the delivery of compounds directly into the intestinal lumen or the aspiration of intestinal fluids in human subjects. Such research provides insights about (local) dynamic metabolic and other intestinal luminal processes, but working with catheters might pose challenges to biomedical researchers and clinicians. Here, we provide an overview of practical and technical aspects of applying naso- and oro-intestinal catheters for delivery of compounds and sampling luminal fluids from the jejunum, ileum, and colon in vivo. The recent literature was extensively reviewed, and combined with experiences and insights we gained through our own clinical trials. We included 60 studies that involved a total of 720 healthy subjects and 42 patients. Most of the studies investigated multiple intestinal regions (24 studies), followed by studies investigating only the jejunum (21 studies), ileum (13 studies), or colon (2 studies). The ileum and colon used to be relatively inaccessible regions in vivo. Custom-made state-of-the-art catheters are available with numerous options for the design, such as multiple lumina, side holes, and inflatable balloons for catheter progression or isolation of intestinal segments. These allow for multiple controlled sampling and compound delivery options in different intestinal regions. Intestinal catheters were often used for delivery (23 studies), sampling (10 studies), or both (27 studies). Sampling speed decreased with increasing distance from the sampling syringe to the specific intestinal segment (i.e., speed highest in duodenum, lowest in ileum/colon). No serious adverse events were reported in the literature, and a dropout rate of around 10% was found for these types of studies. This review is highly relevant for researchers who are active in various research areas and want to expand their research with the use of intestinal catheters in humans in vivo. Intestinal catheters have been used for decades in human nutrition, physiology, pharmacokinetics, and gut microbiome research, facilitating the delivery of compounds directly into the intestinal lumen or the aspiration of intestinal fluids in human subjects. Such research provides insights about (local) dynamic metabolic and other intestinal luminal processes, but working with catheters might pose challenges to biomedical researchers and clinicians. Here, we provide an overview of practical and technical aspects of applying naso- and oro-intestinal catheters for delivery of compounds and sampling luminal fluids from the jejunum, ileum, and colon in vivo. The recent literature was extensively reviewed, and combined with experiences and insights we gained through our own clinical trials. We included 60 studies that involved a total of 720 healthy subjects and 42 patients. Most of the studies investigated multiple intestinal regions (24 studies), followed by studies investigating only the jejunum (21 studies), ileum (13 studies), or colon (2 studies). The ileum and colon used to be relatively inaccessible regions in vivo. Custom-made state-of-the-art catheters are available with numerous options for the design, such as multiple lumina, side holes, and inflatable balloons for catheter progression or isolation of intestinal segments. These allow for multiple controlled sampling and compound delivery options in different intestinal regions. Intestinal catheters were often used for delivery (23 studies), sampling (10 studies), or both (27 studies). Sampling speed decreased with increasing distance from the sampling syringe to the specific intestinal segment (i.e., speed highest in duodenum, lowest in ileum/colon). No serious adverse events were reported in the literature, and a dropout rate of around 10% was found for these types of studies. This review is highly relevant for researchers who are active in various research areas and want to expand their research with the use of intestinal catheters in humans in vivo.Intestinal catheters have been used for decades in human nutrition, physiology, pharmacokinetics, and gut microbiome research, facilitating the delivery of compounds directly into the intestinal lumen or the aspiration of intestinal fluids in human subjects. Such research provides insights about (local) dynamic metabolic and other intestinal luminal processes, but working with catheters might pose challenges to biomedical researchers and clinicians. Here, we provide an overview of practical and technical aspects of applying naso- and oro-intestinal catheters for delivery of compounds and sampling luminal fluids from the jejunum, ileum, and colon in vivo. The recent literature was extensively reviewed, and combined with experiences and insights we gained through our own clinical trials. We included 60 studies that involved a total of 720 healthy subjects and 42 patients. Most of the studies investigated multiple intestinal regions (24 studies), followed by studies investigating only the jejunum (21 studies), ileum (13 studies), or colon (2 studies). The ileum and colon used to be relatively inaccessible regions in vivo. Custom-made state-of-the-art catheters are available with numerous options for the design, such as multiple lumina, side holes, and inflatable balloons for catheter progression or isolation of intestinal segments. These allow for multiple controlled sampling and compound delivery options in different intestinal regions. Intestinal catheters were often used for delivery (23 studies), sampling (10 studies), or both (27 studies). Sampling speed decreased with increasing distance from the sampling syringe to the specific intestinal segment (i.e., speed highest in duodenum, lowest in ileum/colon). No serious adverse events were reported in the literature, and a dropout rate of around 10% was found for these types of studies. This review is highly relevant for researchers who are active in various research areas and want to expand their research with the use of intestinal catheters in humans in vivo. |
| Author | Wilms, Ellen Brummer, Robert Jan Masclee, Ad Am Troost, Freddy J van Trijp, Mara PH Ríos-Morales, Melany Witteman, Ben JM Hooiveld, Guido Jej |
| Author_xml | – sequence: 1 givenname: Mara PH surname: van Trijp fullname: van Trijp, Mara PH organization: Division of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands – sequence: 2 givenname: Ellen surname: Wilms fullname: Wilms, Ellen organization: Division Gastroenterology-Hepatology, Department of Internal Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands – sequence: 3 givenname: Melany surname: Ríos-Morales fullname: Ríos-Morales, Melany organization: Laboratory of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands – sequence: 4 givenname: Ad Am orcidid: 0000-0001-5819-0116 surname: Masclee fullname: Masclee, Ad Am organization: Division Gastroenterology-Hepatology, Department of Internal Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands – sequence: 5 givenname: Robert Jan orcidid: 0000-0002-0362-0008 surname: Brummer fullname: Brummer, Robert Jan organization: Nutrition-Gut-Brain Interactions Research Centre, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden – sequence: 6 givenname: Ben JM orcidid: 0000-0002-1341-8540 surname: Witteman fullname: Witteman, Ben JM organization: Division of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands – sequence: 7 givenname: Freddy J orcidid: 0000-0002-0018-5557 surname: Troost fullname: Troost, Freddy J organization: Division Gastroenterology-Hepatology, Department of Internal Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands – sequence: 8 givenname: Guido Jej orcidid: 0000-0003-1954-3542 surname: Hooiveld fullname: Hooiveld, Guido Jej email: ben.witteman@wur.nl organization: Division of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34036315$$D View this record in MEDLINE/PubMed https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-91945$$DView record from Swedish Publication Index |
| BookMark | eNp1kstuEzEUhi1URNPCjjWyxIZFh_o6FxaVqpabVIkNZWt5PGcSRxN7ajtBeRzeFE8SSlvBwrKs8_2_z-0EHTnvAKHXlLynpOHnemncubvTLRXNMzSjDa8Lzkh1hGaEEFY0tJTH6CTGJSGUibp8gY65ILzkVM7Qr9to3Rw7HX2BteuwD76wLkFM1ukBG50WkCBEbB0eF9to_eDn1uRQgAg6mAXufcAPJB0MdgNhu7OLejUO0w9ZvrEb_wGPQZu0M5jiCczC7V9xBJMiTh63gI130XYQoHuJnvd6iPDqcJ-i208fv199KW6-ff56dXlTGNGUqRCyLBtRQ8uENL2upGlbxllXVqatKtnXBmoh-6ZjTNCy47xlpmK8z10ra8GBn6KzvW_8CeO6VWOwKx22ymurru2PS-XDPJ-1amgjZMYv9nhmV9AZcCno4ZHqccTZhZr7jaoFqWvRZIN3B4Pg79a5eWplo4Fh0A78OiomOWOyljv07RN06dch93qictU0L0KVqTcPM7pP5c-w_1Zogo8xQH-PUKKmXVLTLqnDLmWcPcGNTTpZP9Vjh_-Jyr0I8qg2FoKKxoIz0NmQx6s6b_8t_A3Lfea8 |
| CitedBy_id | crossref_primary_10_1111_nmo_14758 crossref_primary_10_1080_19490976_2024_2350173 crossref_primary_10_1186_s12944_021_01609_3 crossref_primary_10_1016_j_cdnut_2025_104564 crossref_primary_10_1136_gutjnl_2021_326789 crossref_primary_10_1113_JP286101 crossref_primary_10_1016_j_isci_2024_109208 crossref_primary_10_1021_acs_jafc_4c03881 crossref_primary_10_1080_10408398_2024_2433598 |
| Cites_doi | 10.1093/ajcn/72.4.954 10.1016/j.clnu.2011.12.003 10.1159/000197443 10.1038/nrgastro.2012.57 10.1016/j.ejps.2008.07.005 10.1128/AEM.67.10.4939-4942.2001 10.1093/jn/137.3.594 10.1038/nutd.2015.6 10.1016/j.ejrad.2011.11.049 10.1016/j.xphs.2016.03.027 10.1016/S0928-0987(02)00005-2 10.1042/CS20160263 10.1021/acs.molpharmaceut.6b00514 10.1111/j.1368-5031.2005.00751b.x 10.1152/ajpgi.00408.2004 10.1111/dom.13567 10.1097/00006199-198009000-00003 10.1007/PL00009598 10.1111/jphp.12929 10.1111/nmo.12470 10.1186/s12967-017-1175-y 10.3945/jn.115.211615 10.1016/j.addr.2013.12.007 10.1159/000198347 10.1016/j.regpep.2008.02.006 10.1038/ejcn.2013.270 10.1038/ajg.2013.257 10.1155/2018/1671483 10.1053/j.gastro.2019.05.068 10.1152/ajpgi.00127.2010 10.1093/ajcn/81.1.87 10.1089/tmj.2007.0118 10.1016/j.clpt.2004.04.013 10.1177/0091270004265645 10.1211/0022357056631 10.1016/j.ijpharm.2007.04.002 10.1016/j.jpeds.2006.01.050 10.1097/MPG.0b013e3181d336d2 10.1038/s41598-017-13587-7 10.1038/ijo.2014.112 10.1259/bjr/54736800 10.1016/S0016-5085(66)80093-8 10.1038/ijo.2016.196 10.1016/0016-5085(92)91097-N 10.1007/BF02231100 10.4174/jkss.2012.82.3.149 10.1046/j.1365-2036.2000.00763.x 10.1007/s11095-006-9607-z 10.1093/jn/131.6.1706 10.1016/j.gie.2011.03.001 10.1136/gut.35.12.1747 10.1371/journal.pbio.1002533 10.1055/s-2007-1001306 10.3945/jn.115.216838 10.1007/s00455-015-9607-4 10.1080/17474124.2018.1412828 10.1017/S0007114511002054 10.1136/gut.28.10.1221 10.1211/jpp.58.8.0009 10.3945/ajcn.114.106203 10.1021/mp400341t 10.1152/ajpgi.00422.2002 10.1097/MCO.0000000000000393 10.1007/s00276-002-0057-y 10.3945/ajcn.117.157248 10.1590/S1807-59322007000100008 10.1016/j.crad.2006.11.007 10.1007/BF01295717 10.1128/mSphere.00126-19 10.1096/fasebj.28.1_supplement.916.4 10.1210/jc.2012-3961 10.1016/j.rcl.2015.06.008 10.12688/f1000research.17870.2 10.1186/s12876-018-0766-2 10.1007/s10350-005-0215-5 10.1067/mcp.2003.27 10.1067/mcp.2002.121370 10.1152/japplphysiol.00761.2004 10.3945/ajcn.2009.28941 10.1007/BF03000444 10.1016/0016-5085(83)90382-7 10.1038/ijo.2008.166 10.1371/journal.pone.0167775 10.1152/ajpgi.00446.2001 10.3945/ajcn.111.033472 10.1038/ismej.2011.212 10.3945/ajcn.2008.27335 10.1016/j.peptides.2016.10.010 10.1016/j.jcmgh.2019.07.006 10.1177/0884533608314535 10.1016/j.ejps.2012.04.005 10.1038/ctg.2015.54 10.1177/0148607100024004240 10.1093/ajcn/nqz268 10.1067/mge.2001.111773 10.1139/W08-050 10.1023/A:1011020025338 10.1023/A:1005573229786 10.1007/s12325-018-0802-1 10.1016/j.clnu.2016.01.012 10.1136/gutjnl-2014-307240 10.3390/nu11020472 10.1097/00004836-199806000-00006 10.1038/ejcn.2012.183 10.1002/cncr.20360 10.1136/gut.25.9.936 10.1152/physiolgenomics.00114.2005 10.1046/j.1365-2125.2000.00228.x 10.1177/145749691210100302 10.1113/JP272613 10.1016/j.arcmed.2016.06.005 10.1111/j.1445-5994.1983.tb02610.x 10.1023/A:1018888726646 10.1067/mcp.2001.117937 10.1053/gast.2002.34233 10.4253/wjge.v2.i5.155 10.1016/0016-5085(82)90314-6 10.1139/y91-015 10.1345/aph.18003 10.1007/BF03000054 |
| ContentType | Journal Article |
| Copyright | 2021 American Society for Nutrition. The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition. Copyright American Society for Clinical Nutrition, Inc. Sep 2021 The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition. 2021 |
| Copyright_xml | – notice: 2021 American Society for Nutrition. – notice: The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition. – notice: Copyright American Society for Clinical Nutrition, Inc. Sep 2021 – notice: The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition. 2021 |
| DBID | 6I. AAFTH AAYXX CITATION CGR CUY CVF ECM EIF NPM 7QP 7T7 7TS 8FD C1K FR3 K9. NAPCQ P64 7X8 5PM AABEP ADTPV AOWAS D8T D91 ZZAVC |
| DOI | 10.1093/ajcn/nqab149 |
| DatabaseName | ScienceDirect Open Access Titles Elsevier:ScienceDirect:Open Access CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Calcium & Calcified Tissue Abstracts Industrial and Applied Microbiology Abstracts (Microbiology A) Physical Education Index Technology Research Database Environmental Sciences and Pollution Management Engineering Research Database ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Premium Biotechnology and BioEngineering Abstracts MEDLINE - Academic PubMed Central (Full Participant titles) SWEPUB Örebro universitet full text SwePub SwePub Articles SWEPUB Freely available online SWEPUB Örebro universitet SwePub Articles full text |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Nursing & Allied Health Premium Technology Research Database ProQuest Health & Medical Complete (Alumni) Engineering Research Database Industrial and Applied Microbiology Abstracts (Microbiology A) Calcium & Calcified Tissue Abstracts Physical Education Index Biotechnology and BioEngineering Abstracts Environmental Sciences and Pollution Management MEDLINE - Academic |
| DatabaseTitleList | MEDLINE Nursing & Allied Health Premium MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Diet & Clinical Nutrition |
| EISSN | 1938-3207 |
| EndPage | 861 |
| ExternalDocumentID | oai_DiVA_org_oru_91945 PMC8408849 34036315 10_1093_ajcn_nqab149 S0002916522004105 |
| Genre | Research Support, Non-U.S. Gov't Journal Article Review |
| GrantInformation_xml | – fundername: ; |
| GroupedDBID | --- -ET -~X ..I .55 .GJ 0R~ 1HT 23M 2FS 2WC 3O- 4.4 476 48X 53G 5GY 5RE 5VS 6I. 6J9 85S 8R4 8R5 A8Z AABJS AABMN AABZA AACZT AAFTH AAIKC AAJQQ AAMNW AAPGJ AAPQZ AAUQX AAUTI AAVAP AAWDT AAWTL AAXUO AAYOK ABBTP ABDNZ ABJNI ABLJU ABOCM ABPTD ABSAR ABSGY ABWST ACFRR ACGFO ACGFS ACGOD ACIMA ACNCT ACPRK ACPVT ACUFI ACUTJ ADBBV ADEIU ADGZP ADHUB ADRTK ADVEK AEGXH AENEX AETBJ AFDAS AFFDN AFFNX AFFZL AFMIJ AFOFC AFRAH AFXAL AGINJ AGNAY AGQXC AGUTN AHMBA AHPSJ AI. AIAGR AIKOY AIMBJ AJEEA ALMA_UNASSIGNED_HOLDINGS AMRAJ ANFBD AQDSO AQKUS ASMCH AZQFJ BAWUL BAYMD BCRHZ BEYMZ BKOMP BTRTY BYORX C1A CASEJ CDBKE DAKXR DIK DPPUQ E3Z EBS EIHJH EJD ENERS EX3 F5P F9R FDB FECEO FLUFQ FOEOM FOTVD FQBLK FRP G8K GAUVT GJXCC GX1 HF~ HZ~ I4R IH2 J5H KBUDW KOP KQ8 KSI KSN L7B LPU MBLQV MHKGH MV1 MVM N4W NEJ NHB NHCRO NOMLY NOYVH NVLIB O9- ODMLO OHT OJZSN OK1 OVD P2P P6G PCD PQQKQ PRG Q2X R0Z RHF RHI RNS ROL ROX SJN SV3 TCN TEORI TMA TNT TR2 TWZ UBH UHB UKR VH1 W2D W8F WH7 WHG WOQ WOW X7M XOL XSW YBU YHG YOJ YQJ YRY YSK YV5 YYQ YZZ ZA5 ZCA ZCG ZGI ZUP ZXP ~KM AAGQS AAHBH AALRI AAYWO AAYXX ABDPE ABIME ACVFH ADCNI ADMTO ADUKH ADVLN AEUPX AFJKZ AFPUW AGCQF AGKRT AIGII AITUG AKBMS AKRWK AKYEP APXCP CITATION H13 NU- YR5 CGR CUY CVF ECM EIF NPM Z5M 7QP 7T7 7TS 8FD C1K EFKBS FR3 K9. NAPCQ P64 7X8 5PM AABEP ADTPV AOWAS D8T D91 ZZAVC |
| ID | FETCH-LOGICAL-c496t-4566948eb245cfa75cbb232d67cb775f8ce845f9d22416d33b2c723f1496843e3 |
| ISSN | 0002-9165 1938-3207 |
| IngestDate | Thu Aug 21 06:48:12 EDT 2025 Thu Aug 21 14:30:07 EDT 2025 Fri Jul 11 12:13:12 EDT 2025 Fri Jul 25 08:05:19 EDT 2025 Wed Feb 19 02:25:39 EST 2025 Thu Apr 24 23:07:30 EDT 2025 Tue Jul 01 00:53:03 EDT 2025 Fri Feb 23 02:36:51 EST 2024 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 3 |
| Keywords | ileum delivery GI AE TMPD intestinal catheter PEG trials aspiration colon NaCl small intestine human |
| Language | English |
| License | https://creativecommons.org/licenses/by-nc/4.0 The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c496t-4566948eb245cfa75cbb232d67cb775f8ce845f9d22416d33b2c723f1496843e3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23 |
| ORCID | 0000-0001-5819-0116 0000-0002-0018-5557 0000-0002-1341-8540 0000-0003-1954-3542 0000-0002-0362-0008 |
| OpenAccessLink | https://pubmed.ncbi.nlm.nih.gov/PMC8408849 |
| PMID | 34036315 |
| PQID | 2569411097 |
| PQPubID | 41076 |
| PageCount | 19 |
| ParticipantIDs | swepub_primary_oai_DiVA_org_oru_91945 pubmedcentral_primary_oai_pubmedcentral_nih_gov_8408849 proquest_miscellaneous_2532258549 proquest_journals_2569411097 pubmed_primary_34036315 crossref_primary_10_1093_ajcn_nqab149 crossref_citationtrail_10_1093_ajcn_nqab149 elsevier_sciencedirect_doi_10_1093_ajcn_nqab149 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2021-09-01 |
| PublicationDateYYYYMMDD | 2021-09-01 |
| PublicationDate_xml | – month: 09 year: 2021 text: 2021-09-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States – name: Bethesda |
| PublicationTitle | The American journal of clinical nutrition |
| PublicationTitleAlternate | Am J Clin Nutr |
| PublicationYear | 2021 |
| Publisher | Elsevier Inc American Society for Clinical Nutrition, Inc Oxford University Press |
| Publisher_xml | – name: Elsevier Inc – name: American Society for Clinical Nutrition, Inc – name: Oxford University Press |
| References | Borg, Bound, Grivell, Sun, Jones, Horowitz, Rayner, Wu (bib16) 2019; 21 Kawamura, Sekiguchi, Itoh, Omura (bib86) 1993; 38 von Richter, Greiner, Fromm, Fraser, Omari, Barclay, Dent, Somogyi, Eichelbaum (bib52) 2001; 70 Kerlin, Zinsmeister, Phillips (bib106) 1982; 82 Crosby, Kugler (bib117) 1957; 2 Tang, Jin, Wang, Liu, Liu, Wang, Cao (bib127) 2020; 10 van Avesaat, Ripken, Hendriks, Masclee, Troost (bib24) 2017; 41 Glaeser, Drescher, Hofmann, Heinkele, Somogyi, Eichelbaum, Fromm (bib49) 2004; 76 Abbott, Karr, Miller (bib102) 1937; 4 Nagy, Ramos, Courtet-Compondu, Braga-Lagache, Redeuil, Lobo, Azpiroz, Malagelada, Beaumont, Moulin (bib1) 2013; 67 König, Holster, Bruins, Brummer (bib97) 2017; 7 Wood (bib57) 2005; 59 Cooper, Levitan, Fordtran, Ingelfinger (bib44) 1966; 50 Long, Yu, Cui, Jagessar, Zhang, Ji, Huang, Zhang (bib98) 2018; 18 Drescher, Glaeser, Murdter, Hitzl, Eichelbaum, Fromm (bib50) 2003; 73 Shi, Liu, Ding, Li (bib81) 2012; 81 Matsson, Eriksson, Palm, Artursson, Karlgren, Lazorova, Brannstrom, Ekdahl, Duner, Knutson (bib46) 2013; 10 Bos, Airinei, Mariotti, Benamouzig, Berot, Evrard, Fenart, Tome, Gaudichon (bib89) 2007; 137 Rochet, Rigottier-Gois, Levenez, Cadiou, Marteau, Bresson, Goupil-Feillerat, Dore (bib74) 2008; 54 Matsushita, Mori, Tahashi, Wakamatsu, Okazaki (bib82) 2011; 74 Bos, Juillet, Fouillet, Turlan, Dare, Luengo, N’Tounda, Benamouzig, Gausseres, Tome (bib78) 2005; 81 Sender, Fuchs, Milo (bib111) 2016; 14 Seidegard, Nyberg, Borga (bib33) 2008; 35 Gore, Silvers, Thakrar, Wenzke, Mehta, Newmark, Berlin (bib79) 2015; 53 Ge, Tian, Ding, Gu, Wei, Gong, Zhu, Li, Li (bib17) 2016; 47 Hens, Corsetti, Brouwers, Augustijns (bib96) 2016; 105 Braegger, Decsi, Dias, Hartman, Kolacek, Koletzko, Koletzko, Mihatsch, Moreno, Puntis (bib25) 2010; 51 Zilberstein, Quintanilha, Santos, Pajecki, Moura, Alves, Maluf, de Souza, Gama-Rodrigues (bib30) 2007; 62 Gaudichon, Bos, Morens, Petzke, Mariotti, Everwand, Benamouzig, Dare, Tome, Metges (bib104) 2002; 123 . Maljaars, Peters, Kodde, Geraedts, Troost, Haddeman, Masclee (bib35) 2011; 106 Boets, Gomand, Deroover, Preston, Vermeulen, De Preter, Hamer, Van den Mooter, De Vuyst, Courtin (bib123) 2017; 595 Campo, Montserrat, Brullet (bib55) 1998; 30 Tack, Janssens, Vantrappen, Peeters, Annese, Depoortere, Muls, Bouillon (bib85) 1992; 103 Schönfeld, Evans, Wingate (bib22) 1997; 42 Smithard, Barrett, Hargroves, Elliot (bib70) 2015; 30 Cui, Zheng, Hou, Zhuang, Pi, Yang (bib126) 2008; 14 Lee, Hossain, Wang, Sedek (bib92) 2004; 44 Nejad, Oliveira, Sadeqi, Dehkharghani, Kondova, Langermans, Guasto, Tzipori, Widmer, Sonkusale (bib128) 2019; 1 Singh, Chang, Yan, Lee, Ucmak, Wong, Abrouk, Farahnik, Nakamura, Zhu (bib7) 2017; 15 Mariotti, Pueyo, Tome, Berot, Benamouzig, Mahe (bib28) 2001; 131 Dahlgren, Roos, Lundqvist, Abrahamsson, Tannergren, Hellstrom, Sjogren, Lennernas (bib31) 2016; 13 Luttikhold, van Norren, Buijs, Ankersmit, Heijboer, Gootjes, Rijna, van Leeuwen, van Loon (bib2) 2015; 145 Marteau, Flourié, Cherbut, Corrèze, Pellier, Seylaz, Rambaud (bib105) 1994; 35 Oberli, Marsset-Baglieri, Airinei, Sante-Lhoutellier, Khodorova, Remond, Foucault-Simonin, Piedcoq, Tome, Fromentin (bib39) 2015; 145 Kastl, Terry, Wu, Albenberg (bib91) 2020; 9 Wilms, Gerritsen, Smidt, Besseling-van der Vaart, Rijkers, Garcia Fuentes, Masclee, Troost (bib13) 2016; 11 Troost, Saris, Haenen, Bast, Brummer (bib15) 2003; 285 Edwards, Grundy, Grassby, Vasilopoulou, Frost, Butterworth, Berry, Sanderson, Ellis (bib121) 2015; 102 Flourie, Vidon, Florent, Bernier (bib4) 1984; 25 Seekatz, Schnizlein, Koenigsknecht, Baker, Hasler, Bleske, Young, Sun (bib20) 2019; 4 Modigliani, Rambaud, Bernier (bib45) 1973; 9 Walmsley, Montgomery (bib100) 1998; 26 Marteau, Pochart, Dore, Bera-Maillet, Bernalier, Corthier (bib37) 2001; 67 Vasapolli, Schütte, Schulz, Vital, Schomburg, Pieper, Vilchez-Vargas, Malfertheiner (bib9) 2019; 157 Poppitt, Shin, McGill, Budgett, Lo, Pahl, Duxfield, Lane, Ingram (bib58) 2017; 106 Bergman, Forsell, Persson, Knutson, Dickinson, Smith, Swaisland, Farmer, Cantarini, Lennernas (bib53) 2007; 341 Mahadeva, Malik, Hilmi, Qua, Wong, Goh (bib69) 2008; 23 Miner-Williams, Deglaire, Benamouzig, Fuller, Tome, Moughan (bib76) 2012; 96 Hounnou, Destrieux, Desmé, Bertrand, Velut (bib94) 2002; 24 Perez de la Cruz Moreno, Oth, Deferme, Lammert, Tack, Dressman, Augustijns (bib26) 2010; 58 Lennernas, Knutson, Knutson, Hussain, Lesko, Salmonson, Amidon (bib48) 2002; 15 Wolever, Brighenti, Royall, Jenkins, Jenkins (bib113) 1989; 84 Huggins, Tuomi, Young (bib101) 1999; 14 Barone (bib83) 1999; 33 Cohen, Alexander, Catto, Mannion (bib62) 2000; 24 Minko, Pagano, Caceres, Adar, Márquez (bib95) 2014; 28 Chaikomin, Wu, Doran, Meyer, Jones, Feinle-Bisset, Horowitz, Rayner (bib60) 2008; 150 Chalet, Rubbens, Tack, Duchateau, Augustijns (bib8) 2018; 70 Kerlin, Tucker, Phillips (bib110) 1983; 13 Maljaars, Romeyn, Haddeman, Peters, Masclee (bib36) 2009; 89 Ripken, van Avesaat, Troost, Masclee, Witkamp, Hendriks (bib11) 2017; 36 Brouwers, Ingels, Tack, Augustijns (bib27) 2010; 57 Slater, Betts, D’Costa (bib93) 2012; 85 Zoetendal, Raes, van den Bogert, Arumugam, Booijink, Troost, Bork, Wels, de Vos, Kleerebezem (bib122) 2012; 6 Knutson, Koenders, Fridblom, Viberg, Sein, Lennernas (bib47) 2010; 92 Miner-Williams, Deglaire, Benamouzig, Fuller, Tome, Moughan (bib73) 2014; 68 Deglaire, Moughan, Airinei, Benamouzig, Tome (bib75) 2020; 111 Prabhakaran, Doraiswamy, Nagaraja, Cipolla, Ofurum, Evans, Lindsey, Seamon, Kavuturu, Gerlach (bib99) 2012; 101 Jacobs, Rozenblit, Ricci, Roberts, Milikow, Chernyak, Wolf (bib80) 2007; 62 van Avesaat, Troost, Ripken, Hendriks, Masclee (bib14) 2015; 39 Glaeser, Drescher, van der Kuip, Behrens, Geick, Burk, Dent, Somogyi, Von Richter, Griese (bib51) 2002; 71 Geboes, De Preter, Luypaerts, Bammens, Evenepoel, Ghoos, Rutgeerts, Verbeke (bib90) 2005; 288 Weerts, Keszthelyi, Vork, Aendekerk, Frijlink, Brouwers, Neef, Jonkers, Masclee (bib124) 2018; 35 Lee, Kim (bib87) 2012; 82 Wu, Thazhath, Marathe, Bound, Jones, Horowitz, Rayner (bib40) 2015; 5 Cummings, Pomare, Branch, Naylor, Macfarlane (bib119) 1987; 28 Zarate, Mohammed, O’Shaughnessy, Newell, Yazaki, Williams, Lunniss, Semler, Scott (bib66) 2010; 299 Troost, Brummer, Haenen, Bast, van Haaften, Evelo, Saris (bib68) 2006; 25 Kuo, Castell (bib23) 1995; 90 Baeyens, van de Velde, De Schepper, Wollaert, Reyntjens (bib84) 1979; 55 Shobar, Velineni, Keshavarzian, Swanson, DeMeo, Melson, Losurdo, Engen, Sun, Koenig (bib115) 2016; 7 Maljaars, Symersky, Kee, Haddeman, Peters, Masclee (bib77) 2008; 32 Deloose, Janssen, Depoortere, Tack (bib63) 2012; 9 Wu, Bound, Standfield, Jones, Horowitz, Rayner (bib43) 2013; 98 Vander Noot, Eloubeidi, Chen, Eltoum, Jhala, Jhala, Syed, Chhieng (bib120) 2004; 102 Silk, Perrett, Webb, Clark (bib6) 1974; 46 Jiang, Jiang, Chen, Shi, Shi (bib64) 2018; 2018 Gervasio, Brown, Lima, Tabbaa, Abell, Werkman, Haberer, Hak (bib72) 2000; 45 Drewe, Narjes, Heinzel, Brickl, Rohr, Beglinger (bib59) 2000; 50 [Internet]. National Library of Medicine (US). Identifier NCT04013607, Fiber Fermentation Kinetics Inside the Gut, and Utilization of Bacterial Metabolites; July 10, 2019 [cited 15 March 2020]. Available from Otuya, Verma, Farrokhi, Higgins, Rosenberg, Damman, Tearney (bib118) 2018; 12 Rigda, Trahair, Little, Wu, Standfield, Feinle-Bisset, Rayner, Horowitz, Jones (bib42) 2016; 86 Persson, Nilsson, Hansson, Lofgren, Liback, Knutson, Abrahamsson, Lennernas (bib54) 2006; 23 van den Bogert B. Community and genomic analysis of the human small intestine microbiota. Chapter 7, general discussion. 2013. Ingelfinger, Abbott (bib108) 1940; 7 van der Beek, Canfora, Lenaerts, Troost, Damink, Holst, Masclee, Dejong, Blaak (bib112) 2016; 130 Kagawa-Busby, Heitkemper, Hansen, Hanson, Vanderburg (bib103) 1980; 29 Coeffier, Hecketsweiler, Hecketsweiler, Dechelotte (bib61) 2005; 98 Nissinen, Gylling, Vuoristo, Miettinen (bib65) 2002; 282 Rafferty, Tham (bib67) 2010; 2 Mariotti, Mahe, Luengo, Benamouzig, Tome (bib29) 2000; 72 Hecketsweiler, Vidon, Emonts, Bernier (bib5) 1979; 19 Read, Al Janabi, Bates, Barber (bib109) 1983; 84 Reisz, D’Alessandro (bib12) 2017; 20 Takamatsu, Kim, Welage, Idkaidek, Hayashi, Barnett, Yamamoto, Lipka, Lennernas, Hussain (bib41) 2001; 18 Soma, Saito, Kishibe, Takahashi, Tanaka, Munakata (bib56) 2001; 53 Deloose, Vos, Corsetti, Depoortere, Tack (bib88) 2015; 27 Angelberger, Reinisch, Makristathis, Lichtenberger, Dejaco, Papay, Novacek, Trauner, Loy, Erry (bib18) 2013; 108 Seidegard, Nyberg, Borga (bib32) 2012; 46 Strocchi, Levitt (bib3) 1991; 69 Bucher, Gervaz, Egger, Soravia, Morel (bib114) 2006; 49 Vesa, Pochart, Marteau (bib38) 2000; 14 Jalanka, Salonen, Salojärvi, Ritari, Immonen, Marciani, Gowland, Hoad, Garsed, Lam (bib116) 2015; 64 Dohil, Fidler, Barshop, Gangoiti, Deutsch, Martin, Schneider (bib19) 2006; 148 Byrne, Blunt, Burn, Chambers, Dagbasi, Franco Becker, Gibson, Mendoza, Murphy, Poveda (bib71) 2019; 8 Klaassen, Alleleyn, van Avesaat, Troost, Keszthelyi, Masclee (bib10) 2019; 11 Munoz, Alici, Li (bib125) 2014; 71 Maljaars, van der Wal, Wiersma, Peters, Haddeman, Masclee (bib34) 2012; 31 Nejad (10.1093/ajcn/nqab149_bib128) 2019; 1 Strocchi (10.1093/ajcn/nqab149_bib3) 1991; 69 Dahlgren (10.1093/ajcn/nqab149_bib31) 2016; 13 Cohen (10.1093/ajcn/nqab149_bib62) 2000; 24 Gore (10.1093/ajcn/nqab149_bib79) 2015; 53 Cooper (10.1093/ajcn/nqab149_bib44) 1966; 50 Persson (10.1093/ajcn/nqab149_bib54) 2006; 23 Jiang (10.1093/ajcn/nqab149_bib64) 2018; 2018 Gervasio (10.1093/ajcn/nqab149_bib72) 2000; 45 König (10.1093/ajcn/nqab149_bib97) 2017; 7 Maljaars (10.1093/ajcn/nqab149_bib36) 2009; 89 Kuo (10.1093/ajcn/nqab149_bib23) 1995; 90 Dohil (10.1093/ajcn/nqab149_bib19) 2006; 148 Knutson (10.1093/ajcn/nqab149_bib47) 2010; 92 Silk (10.1093/ajcn/nqab149_bib6) 1974; 46 Minko (10.1093/ajcn/nqab149_bib95) 2014; 28 Luttikhold (10.1093/ajcn/nqab149_bib2) 2015; 145 Byrne (10.1093/ajcn/nqab149_bib71) 2019; 8 Prabhakaran (10.1093/ajcn/nqab149_bib99) 2012; 101 Matsson (10.1093/ajcn/nqab149_bib46) 2013; 10 Deloose (10.1093/ajcn/nqab149_bib88) 2015; 27 van Avesaat (10.1093/ajcn/nqab149_bib24) 2017; 41 Takamatsu (10.1093/ajcn/nqab149_bib41) 2001; 18 Matsushita (10.1093/ajcn/nqab149_bib82) 2011; 74 Hounnou (10.1093/ajcn/nqab149_bib94) 2002; 24 Crosby (10.1093/ajcn/nqab149_bib117) 1957; 2 Jalanka (10.1093/ajcn/nqab149_bib116) 2015; 64 Tang (10.1093/ajcn/nqab149_bib127) 2020; 10 Zilberstein (10.1093/ajcn/nqab149_bib30) 2007; 62 von Richter (10.1093/ajcn/nqab149_bib52) 2001; 70 Oberli (10.1093/ajcn/nqab149_bib39) 2015; 145 Singh (10.1093/ajcn/nqab149_bib7) 2017; 15 Brouwers (10.1093/ajcn/nqab149_bib27) 2010; 57 Marteau (10.1093/ajcn/nqab149_bib37) 2001; 67 Troost (10.1093/ajcn/nqab149_bib15) 2003; 285 10.1093/ajcn/nqab149_bib107 Zarate (10.1093/ajcn/nqab149_bib66) 2010; 299 Jacobs (10.1093/ajcn/nqab149_bib80) 2007; 62 Vasapolli (10.1093/ajcn/nqab149_bib9) 2019; 157 Shi (10.1093/ajcn/nqab149_bib81) 2012; 81 Rochet (10.1093/ajcn/nqab149_bib74) 2008; 54 Borg (10.1093/ajcn/nqab149_bib16) 2019; 21 van der Beek (10.1093/ajcn/nqab149_bib112) 2016; 130 Shobar (10.1093/ajcn/nqab149_bib115) 2016; 7 Seidegard (10.1093/ajcn/nqab149_bib33) 2008; 35 Bos (10.1093/ajcn/nqab149_bib89) 2007; 137 Otuya (10.1093/ajcn/nqab149_bib118) 2018; 12 Abbott (10.1093/ajcn/nqab149_bib102) 1937; 4 Angelberger (10.1093/ajcn/nqab149_bib18) 2013; 108 Campo (10.1093/ajcn/nqab149_bib55) 1998; 30 Drewe (10.1093/ajcn/nqab149_bib59) 2000; 50 Seekatz (10.1093/ajcn/nqab149_bib20) 2019; 4 Chalet (10.1093/ajcn/nqab149_bib8) 2018; 70 Sender (10.1093/ajcn/nqab149_bib111) 2016; 14 Drescher (10.1093/ajcn/nqab149_bib50) 2003; 73 Ingelfinger (10.1093/ajcn/nqab149_bib108) 1940; 7 Wood (10.1093/ajcn/nqab149_bib57) 2005; 59 Edwards (10.1093/ajcn/nqab149_bib121) 2015; 102 Smithard (10.1093/ajcn/nqab149_bib70) 2015; 30 Long (10.1093/ajcn/nqab149_bib98) 2018; 18 Glaeser (10.1093/ajcn/nqab149_bib49) 2004; 76 Kawamura (10.1093/ajcn/nqab149_bib86) 1993; 38 Ripken (10.1093/ajcn/nqab149_bib11) 2017; 36 Zoetendal (10.1093/ajcn/nqab149_bib122) 2012; 6 Maljaars (10.1093/ajcn/nqab149_bib35) 2011; 106 Maljaars (10.1093/ajcn/nqab149_bib77) 2008; 32 Geboes (10.1093/ajcn/nqab149_bib90) 2005; 288 Wu (10.1093/ajcn/nqab149_bib43) 2013; 98 Lennernas (10.1093/ajcn/nqab149_bib48) 2002; 15 Mahadeva (10.1093/ajcn/nqab149_bib69) 2008; 23 Lee (10.1093/ajcn/nqab149_bib87) 2012; 82 Tack (10.1093/ajcn/nqab149_bib85) 1992; 103 Maljaars (10.1093/ajcn/nqab149_bib34) 2012; 31 Wilms (10.1093/ajcn/nqab149_bib13) 2016; 11 Deloose (10.1093/ajcn/nqab149_bib63) 2012; 9 Nissinen (10.1093/ajcn/nqab149_bib65) 2002; 282 Glaeser (10.1093/ajcn/nqab149_bib51) 2002; 71 Braegger (10.1093/ajcn/nqab149_bib25) 2010; 51 Slater (10.1093/ajcn/nqab149_bib93) 2012; 85 Kerlin (10.1093/ajcn/nqab149_bib110) 1983; 13 Troost (10.1093/ajcn/nqab149_bib68) 2006; 25 Barone (10.1093/ajcn/nqab149_bib83) 1999; 33 Baeyens (10.1093/ajcn/nqab149_bib84) 1979; 55 Vander Noot (10.1093/ajcn/nqab149_bib120) 2004; 102 Modigliani (10.1093/ajcn/nqab149_bib45) 1973; 9 Lee (10.1093/ajcn/nqab149_bib92) 2004; 44 Klaassen (10.1093/ajcn/nqab149_bib10) 2019; 11 Cummings (10.1093/ajcn/nqab149_bib119) 1987; 28 Wu (10.1093/ajcn/nqab149_bib40) 2015; 5 Bos (10.1093/ajcn/nqab149_bib78) 2005; 81 Soma (10.1093/ajcn/nqab149_bib56) 2001; 53 10.1093/ajcn/nqab149_bib21 Schönfeld (10.1093/ajcn/nqab149_bib22) 1997; 42 Chaikomin (10.1093/ajcn/nqab149_bib60) 2008; 150 Bergman (10.1093/ajcn/nqab149_bib53) 2007; 341 Gaudichon (10.1093/ajcn/nqab149_bib104) 2002; 123 Mariotti (10.1093/ajcn/nqab149_bib28) 2001; 131 Rigda (10.1093/ajcn/nqab149_bib42) 2016; 86 Kerlin (10.1093/ajcn/nqab149_bib106) 1982; 82 Walmsley (10.1093/ajcn/nqab149_bib100) 1998; 26 Munoz (10.1093/ajcn/nqab149_bib125) 2014; 71 Kagawa-Busby (10.1093/ajcn/nqab149_bib103) 1980; 29 Cui (10.1093/ajcn/nqab149_bib126) 2008; 14 Marteau (10.1093/ajcn/nqab149_bib105) 1994; 35 Miner-Williams (10.1093/ajcn/nqab149_bib73) 2014; 68 Boets (10.1093/ajcn/nqab149_bib123) 2017; 595 Read (10.1093/ajcn/nqab149_bib109) 1983; 84 Perez de la Cruz Moreno (10.1093/ajcn/nqab149_bib26) 2010; 58 Hens (10.1093/ajcn/nqab149_bib96) 2016; 105 Hecketsweiler (10.1093/ajcn/nqab149_bib5) 1979; 19 Poppitt (10.1093/ajcn/nqab149_bib58) 2017; 106 Miner-Williams (10.1093/ajcn/nqab149_bib76) 2012; 96 Vesa (10.1093/ajcn/nqab149_bib38) 2000; 14 Nagy (10.1093/ajcn/nqab149_bib1) 2013; 67 Reisz (10.1093/ajcn/nqab149_bib12) 2017; 20 Coeffier (10.1093/ajcn/nqab149_bib61) 2005; 98 Seidegard (10.1093/ajcn/nqab149_bib32) 2012; 46 Wolever (10.1093/ajcn/nqab149_bib113) 1989; 84 Ge (10.1093/ajcn/nqab149_bib17) 2016; 47 Kastl (10.1093/ajcn/nqab149_bib91) 2020; 9 Deglaire (10.1093/ajcn/nqab149_bib75) 2020; 111 Mariotti (10.1093/ajcn/nqab149_bib29) 2000; 72 Rafferty (10.1093/ajcn/nqab149_bib67) 2010; 2 Weerts (10.1093/ajcn/nqab149_bib124) 2018; 35 Huggins (10.1093/ajcn/nqab149_bib101) 1999; 14 Bucher (10.1093/ajcn/nqab149_bib114) 2006; 49 van Avesaat (10.1093/ajcn/nqab149_bib14) 2015; 39 Flourie (10.1093/ajcn/nqab149_bib4) 1984; 25 |
| References_xml | – volume: 82 start-page: 701 year: 1982 end-page: 706 ident: bib106 article-title: Relationship of motility to flow of contents in the human small intestine publication-title: Gastroenterology. – volume: 288 start-page: G994 year: 2005 end-page: G999 ident: bib90 article-title: Validation of lactose[15N,15N]ureide as a tool to study colonic nitrogen metabolism publication-title: Am J Physiol Gastrointest Liver Physiol. – volume: 76 start-page: 230 year: 2004 end-page: 238 ident: bib49 article-title: Impact of concentration and rate of intraluminal drug delivery on absorption and gut wall metabolism of verapamil in humans publication-title: Clin Pharmacol Ther. – volume: 26 start-page: 253 year: 1998 end-page: 255 ident: bib100 article-title: Factors affecting patient tolerance of upper gastrointestinal endoscopy publication-title: J Clin Gastroenterol. – volume: 54 start-page: 660 year: 2008 end-page: 667 ident: bib74 article-title: Modulation of publication-title: Can J Microbiol. – volume: 111 start-page: 90 year: 2020 end-page: 97 ident: bib75 article-title: Intact and hydrolyzed casein lead to similar ileal endogenous protein and amino acid flows in adult humans publication-title: Am J Clin Nutr. – volume: 64 start-page: 1562 year: 2015 end-page: 1568 ident: bib116 article-title: Effects of bowel cleansing on the intestinal microbiota publication-title: Gut. – volume: 67 start-page: 4939 year: 2001 end-page: 4942 ident: bib37 article-title: Comparative study of bacterial groups within the human cecal and fecal microbiota publication-title: Appl Environ Microbiol. – volume: 53 start-page: 1225 year: 2015 end-page: 1240 ident: bib79 article-title: Bowel obstruction publication-title: Radiol Clin North Am. – volume: 4 start-page: 742 year: 1937 end-page: 752 ident: bib102 article-title: Intubation studies of the human small intestine: VII. Factors concerned in absorption of glucose from the jejunum and ileum publication-title: Am J Dig Dis. – volume: 299 start-page: G1276 year: 2010 end-page: G1286 ident: bib66 article-title: Accurate localization of a fall in pH within the ileocecal region: validation using a dual-scintigraphic technique publication-title: Am J Physiol Gastrointest Liver Physiol. – volume: 71 start-page: 131 year: 2002 end-page: 140 ident: bib51 article-title: Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transporters publication-title: Clin Pharmacol Ther. – volume: 55 start-page: 19 year: 1979 end-page: 23 ident: bib84 article-title: Effects of intravenous and oral domperidone on the motor function of the stomach and small intestine publication-title: Postgrad Med J. – volume: 10 year: 2020 ident: bib127 article-title: Current sampling methods for gut microbiota: a call for more precise devices publication-title: Front Cell Infect Microbiol. – volume: 21 start-page: 640 year: 2019 end-page: 647 ident: bib16 article-title: Comparative effects of proximal and distal small intestinal administration of metformin on plasma glucose and glucagon-like peptide-1, and gastric emptying after oral glucose, in type 2 diabetes publication-title: Diabetes Obes Metab. – volume: 51 start-page: 110 year: 2010 end-page: 122 ident: bib25 article-title: Practical approach to paediatric enteral nutrition: a comment by the ESPGHAN Committee on Nutrition publication-title: J Pediatr Gastroenterol Nutr. – volume: 45 start-page: 1601 year: 2000 end-page: 1607 ident: bib72 article-title: Sequential group trial to determine gastrointestinal site of absorption and systemic exposure of azathioprine publication-title: Dig Dis Sci. – volume: 50 start-page: 69 year: 2000 end-page: 72 ident: bib59 article-title: Absorption of lefradafiban from different sites of the gastrointestinal tract publication-title: Br J Clin Pharmacol. – reference: van den Bogert B. Community and genomic analysis of the human small intestine microbiota. Chapter 7, general discussion. 2013. – volume: 18 start-page: 1 year: 2018 end-page: 6 ident: bib98 article-title: A novel quick transendoscopic enteral tubing in mid-gut: technique and training with video publication-title: BMC Gastroenterol. – volume: 108 start-page: 1620 year: 2013 end-page: 1630 ident: bib18 article-title: Temporal bacterial community dynamics vary among ulcerative colitis patients after fecal microbiota transplantation publication-title: Am J Gastroenterol. – volume: 31 start-page: 535 year: 2012 end-page: 542 ident: bib34 article-title: The effect of lipid droplet size on satiety and peptide secretion is intestinal site-specific publication-title: Clin Nutr. – volume: 29 start-page: 276 year: 1980 end-page: 280 ident: bib103 article-title: Effects of diet temperature on tolerance of enteral feedings publication-title: Nurs Res. – volume: 106 start-page: 1609 year: 2011 end-page: 1615 ident: bib35 article-title: Length and site of the small intestine exposed to fat influences hunger and food intake publication-title: Br J Nutr. – volume: 98 start-page: E718 year: 2013 end-page: E722 ident: bib43 article-title: Effects of taurocholic acid on glycemic, glucagon-like peptide-1, and insulin responses to small intestinal glucose infusion in healthy humans publication-title: J Clin Endocrinol Metab. – volume: 285 start-page: G354 year: 2003 end-page: G359 ident: bib15 article-title: New method to study oxidative damage and antioxidants in the human small bowel: effects of iron application publication-title: Am J Physiol Gastrointest Liver Physiol. – volume: 30 start-page: 448 year: 1998 end-page: 452 ident: bib55 article-title: Transnasal gastroscopy compared to conventional gastroscopy: a randomized study of feasibility, safety, and tolerance publication-title: Endoscopy. – volume: 123 start-page: 50 year: 2002 end-page: 59 ident: bib104 article-title: Ileal losses of nitrogen and amino acids in humans and their importance to the assessment of amino acid requirements publication-title: Gastroenterology. – volume: 86 start-page: 126 year: 2016 end-page: 132 ident: bib42 article-title: Regional specificity of the gut-incretin response to small intestinal glucose infusion in healthy older subjects publication-title: Peptides. – volume: 24 start-page: 290 year: 2002 end-page: 294 ident: bib94 article-title: Anatomical study of the length of the human intestine publication-title: Surg Radiol Anat. – volume: 145 start-page: 2033 year: 2015 end-page: 2038 ident: bib2 article-title: Jejunal casein feeding is followed by more rapid protein digestion and amino acid absorption when compared with gastric feeding in healthy young men publication-title: J Nutr. – volume: 42 start-page: 1613 year: 1997 end-page: 1617 ident: bib22 article-title: Effect of viscous fiber (guar) on postprandial motor activity in human small bowel publication-title: Dig Dis Sci. – volume: 9 start-page: 271 year: 2012 end-page: 285 ident: bib63 article-title: The migrating motor complex: control mechanisms and its role in health and disease publication-title: Nat Rev Gastroenterol Hepatol. – volume: 69 start-page: 108 year: 1991 end-page: 110 ident: bib3 article-title: Measurement of starch absorption in humans publication-title: Can J Physiol Pharmacol. – volume: 101 start-page: 147 year: 2012 end-page: 155 ident: bib99 article-title: Nasoenteric tube complications publication-title: Scand J Surg. – volume: 7 start-page: e143 year: 2016 ident: bib115 article-title: The effects of bowel preparation on microbiota-related metrics differ in health and in inflammatory bowel disease and for the mucosal and luminal microbiota compartments publication-title: Clin Transl Gastroenterol. – volume: 72 start-page: 954 year: 2000 end-page: 962 ident: bib29 article-title: Postprandial modulation of dietary and whole-body nitrogen utilization by carbohydrates in humans publication-title: Am J Clin Nutr. – volume: 103 start-page: 72 year: 1992 end-page: 79 ident: bib85 article-title: Effect of erythromycin on gastric motility in controls and in diabetic gastroparesis publication-title: Gastroenterology. – volume: 15 start-page: 1 year: 2017 end-page: 17 ident: bib7 article-title: Influence of diet on the gut microbiome and implications for human health publication-title: J Transl Med. – volume: 67 start-page: 202 year: 2013 end-page: 206 ident: bib1 article-title: Double-balloon jejunal perfusion to compare absorption of vitamin E and vitamin E acetate in healthy volunteers under maldigestion conditions publication-title: Eur J Clin Nutr. – volume: 11 start-page: 472 year: 2019 ident: bib10 article-title: Intraintestinal delivery of tastants using a naso-duodenal-ileal catheter does not influence food intake or satiety publication-title: Nutrients. – volume: 38 start-page: 1026 year: 1993 end-page: 1031 ident: bib86 article-title: Effect of erythromycin derivative EM523L on human interdigestive gastrointestinal tract publication-title: Dig Dis Sci. – volume: 102 start-page: 791 year: 2015 end-page: 800 ident: bib121 article-title: Manipulation of starch bioaccessibility in wheat endosperm to regulate starch digestion, postprandial glycemia, insulinemia, and gut hormone responses: a randomized controlled trial in healthy ileostomy participants publication-title: Am J Clin Nutr. – volume: 282 start-page: G1009 year: 2002 end-page: G1015 ident: bib65 article-title: Micellar distribution of cholesterol and phytosterols after duodenal plant stanol ester infusion publication-title: Am J Physiol Gastrointest Liver Physiol. – volume: 62 start-page: 353 year: 2007 end-page: 357 ident: bib80 article-title: Small bowel faeces sign in patients without small bowel obstruction publication-title: Clin Radiol. – volume: 105 start-page: 2904 year: 2016 end-page: 2912 ident: bib96 article-title: Gastrointestinal and systemic monitoring of posaconazole in humans after fasted and fed state administration of a solid dispersion publication-title: J Pharm Sci. – volume: 89 start-page: 1019 year: 2009 end-page: 1024 ident: bib36 article-title: Effect of fat saturation on satiety, hormone release, and food intake publication-title: Am J Clin Nutr. – volume: 8 start-page: 258 year: 2019 ident: bib71 article-title: A study protocol for a randomised crossover study evaluating the effect of diets differing in carbohydrate quality on ileal content and appetite regulation in healthy humans publication-title: F1000Res. – volume: 11 start-page: e0167775 year: 2016 ident: bib13 article-title: Effects of supplementation of the synbiotic ecologic(R) 825/FOS P6 on intestinal barrier function in healthy humans: a randomized controlled trial publication-title: PLoS One. – volume: 2 start-page: 155 year: 2010 end-page: 164 ident: bib67 article-title: Endoscopic placement of enteral feeding tubes publication-title: World J Gastrointest Endosc. – volume: 9 start-page: 33 year: 2020 end-page: 45 ident: bib91 article-title: The structure and function of the human small intestinal microbiota: current understanding and future directions publication-title: Cell Mol Gastroenterol Hepatol. – volume: 148 start-page: 764 year: 2006 end-page: 769 ident: bib19 article-title: Understanding intestinal cysteamine bitartrate absorption publication-title: J Pediatr. – volume: 1 start-page: 690982 year: 2019 ident: bib128 article-title: Ingestible osmotic pill for in-vivo sampling of gut microbiome publication-title: BioRxiv. – volume: 46 start-page: 530 year: 2012 end-page: 536 ident: bib32 article-title: Differentiating mucosal and hepatic metabolism of budesonide by local pretreatment with increasing doses of ketoconazole in the proximal jejunum publication-title: Eur J Pharm Sci. – volume: 33 start-page: 429 year: 1999 end-page: 440 ident: bib83 article-title: Domperidone: a peripherally acting dopamine2-receptor antagonist publication-title: Ann Pharmacother. – volume: 30 start-page: 275 year: 2015 end-page: 285 ident: bib70 article-title: Electromagnetic sensor-guided enteral access systems: a literature review publication-title: Dysphagia. – volume: 90 start-page: 1804 year: 1995 end-page: 1807 ident: bib23 article-title: The effect of nasogastric intubation on gastroesophageal reflux: a comparison of different tube sizes publication-title: Am J Gastroenterol. – volume: 46 start-page: 393 year: 1974 end-page: 402 ident: bib6 article-title: Absorption of two tripeptides by the human small intestine: A study using a perfusion technique publication-title: Clin Sci Mol Med. – volume: 53 start-page: 14 year: 2001 end-page: 18 ident: bib56 article-title: Evaluation of topical pharyngeal anesthesia for upper endoscopy including factors associated with patient tolerance publication-title: Gastrointest Endosc. – volume: 130 start-page: 2073 year: 2016 end-page: 2082 ident: bib112 article-title: Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men publication-title: Clin Sci. – volume: 59 start-page: 1373 year: 2005 end-page: 1374 ident: bib57 article-title: New strategy to ease the discomfort of insertion of nasogastric tubes publication-title: Int J Clin Pract. – volume: 9 start-page: 176 year: 1973 end-page: 192 ident: bib45 article-title: The method of intraluminal perfusion of the human small intestine. I. Principle and technique publication-title: Digestion. – volume: 39 start-page: 235 year: 2015 end-page: 243 ident: bib14 article-title: Ileal brake activation: macronutrient-specific effects on eating behavior? publication-title: Int J Obes. – volume: 96 start-page: 508 year: 2012 end-page: 515 ident: bib76 article-title: Endogenous proteins in terminal ileal digesta of adult subjects fed a casein-based diet publication-title: Am J Clin Nutr. – volume: 81 start-page: e370 year: 2012 end-page: e375 ident: bib81 article-title: Magnesium sulfate as an oral contrast medium in magnetic resonance imaging of the small intestine publication-title: Eur J Radiol. – volume: 44 start-page: 599 year: 2004 end-page: 604 ident: bib92 article-title: Absorption of rivastigmine from different regions of the gastrointestinal tract in humans publication-title: J Clin Pharmacol. – volume: 7 start-page: 468 year: 1940 end-page: 474 ident: bib108 article-title: Intubation studies of the human small intestine publication-title: Am J Dig Dis. – volume: 68 start-page: 363 year: 2014 end-page: 369 ident: bib73 article-title: Endogenous proteins in the ileal digesta of adult humans given casein-, enzyme-hydrolyzed casein- or crystalline amino-acid-based diets in an acute feeding study publication-title: Eur J Clin Nutr. – volume: 49 start-page: 109 year: 2006 end-page: 112 ident: bib114 article-title: Morphologic alterations associated with mechanical bowel preparation before elective colorectal surgery: a randomized trial publication-title: Dis Colon Rectum. – volume: 47 start-page: 236 year: 2016 end-page: 242 ident: bib17 article-title: Fecal microbiota transplantation in combination with soluble dietary fiber for treatment of slow transit constipation: a pilot study publication-title: Arch Med Res. – volume: 15 start-page: 271 year: 2002 end-page: 277 ident: bib48 article-title: The effect of amiloride on the in vivo effective permeability of amoxicillin in human jejunum: experience from a regional perfusion technique publication-title: Eur J Pharm Sci. – volume: 41 start-page: 217 year: 2017 end-page: 224 ident: bib24 article-title: Small intestinal protein infusion in humans: evidence for a location-specific gradient in intestinal feedback on food intake and GI peptide release publication-title: Int J Obes. – volume: 10 start-page: 4252 year: 2013 end-page: 4262 ident: bib46 article-title: Combined in vitro–in vivo approach to assess the hepatobiliary disposition of a novel oral thrombin inhibitor publication-title: Mol Pharm. – volume: 73 start-page: 223 year: 2003 end-page: 231 ident: bib50 article-title: P-glycoprotein-mediated intestinal and biliary digoxin transport in humans publication-title: Clin Pharmacol Ther. – volume: 23 start-page: 742 year: 2006 end-page: 751 ident: bib54 article-title: A clinical single-pass perfusion investigation of the dynamic in vivo secretory response to a dietary meal in human proximal small intestine publication-title: Pharm Res. – volume: 28 start-page: 914 year: 2014 end-page: 916 ident: bib95 article-title: Human intestinal tract length and relationship with body height publication-title: FASEB J. – volume: 71 start-page: 77 year: 2014 end-page: 85 ident: bib125 article-title: A review of drug delivery systems for capsule endoscopy publication-title: Adv Drug Deliv Rev. – volume: 70 start-page: 1002 year: 2018 end-page: 1008 ident: bib8 article-title: Intestinal disposition of quercetin and its phase-II metabolites after oral administration in healthy volunteers publication-title: J Pharm Pharmacol. – volume: 14 start-page: 157 year: 1999 end-page: 161 ident: bib101 article-title: Effects of nasogastric tubes on the young, normal swallowing mechanism publication-title: Dysphagia. – volume: 137 start-page: 594 year: 2007 end-page: 600 ident: bib89 article-title: The poor digestibility of rapeseed protein is balanced by its very high metabolic utilization in humans publication-title: J Nutr. – volume: 595 start-page: 541 year: 2017 end-page: 555 ident: bib123 article-title: Systemic availability and metabolism of colonic-derived short-chain fatty acids in healthy subjects: A stable isotope study publication-title: J Physiol. – volume: 2 start-page: 236 year: 1957 end-page: 241 ident: bib117 article-title: Intraluminal biopsy of the small intestine; The intestinal biopsy capsule publication-title: Am J Dig Dis. – volume: 131 start-page: 1706 year: 2001 end-page: 1713 ident: bib28 article-title: The influence of the albumin fraction on the bioavailability and postprandial utilization of pea protein given selectively to humans publication-title: J Nutr. – volume: 13 start-page: 3013 year: 2016 end-page: 3021 ident: bib31 article-title: Regional intestinal permeability of three model drugs in human publication-title: Mol Pharm. – volume: 84 start-page: 1027 year: 1989 end-page: 1033 ident: bib113 article-title: Effect of rectal infusion of short chain fatty acids in human subjects publication-title: Am J Gastroenterol. – volume: 81 start-page: 87 year: 2005 end-page: 94 ident: bib78 article-title: Postprandial metabolic utilization of wheat protein in humans publication-title: Am J Clin Nutr. – volume: 32 start-page: 1633 year: 2008 end-page: 1639 ident: bib77 article-title: Effect of ileal fat perfusion on satiety and hormone release in healthy volunteers publication-title: Int J Obes. – volume: 84 start-page: 1568 year: 1983 end-page: 1572 ident: bib109 article-title: Effect of gastrointestinal intubation on the passage of a solid meal through the stomach and small intestine in humans publication-title: Gastroenterology. – volume: 5 start-page: e156 year: 2015 ident: bib40 article-title: Comparative effect of intraduodenal and intrajejunal glucose infusion on the gut-incretin axis response in healthy males publication-title: Nutr Diabetes. – volume: 35 start-page: 1965 year: 2018 end-page: 1978 ident: bib124 article-title: A novel ileocolonic release peppermint oil capsule for treatment of irritable bowel syndrome: a Phase I study in healthy volunteers publication-title: Adv Ther. – volume: 62 start-page: 47 year: 2007 end-page: 54 ident: bib30 article-title: Digestive tract microbiota in healthy volunteers publication-title: Clinics. – volume: 145 start-page: 2221 year: 2015 end-page: 2228 ident: bib39 article-title: High true ileal digestibility but not postprandial utilization of nitrogen from bovine meat protein in humans is moderately decreased by high-temperature, long-duration cooking publication-title: J Nutr. – volume: 12 start-page: 109 year: 2018 end-page: 117 ident: bib118 article-title: Non-endoscopic biopsy techniques: a review publication-title: Expert Rev Gastroenterol Hepatol. – volume: 7 start-page: 13100 year: 2017 ident: bib97 article-title: Randomized clinical trial: effective gluten degradation by publication-title: Sci Rep. – volume: 27 start-page: 63 year: 2015 end-page: 71 ident: bib88 article-title: Endogenous motilin, but not ghrelin plasma levels fluctuate in accordance with gastric phase III activity of the migrating motor complex in man publication-title: Neurogastroenterol Motil. – volume: 35 start-page: 264 year: 2008 end-page: 270 ident: bib33 article-title: Presystemic elimination of budesonide in man when administered locally at different levels in the gut, with and without local inhibition by ketoconazole publication-title: Eur J Pharm Sci. – volume: 14 start-page: 823 year: 2000 end-page: 828 ident: bib38 article-title: Pharmacokinetics of publication-title: Aliment Pharmacol Ther. – volume: 20 start-page: 366 year: 2017 end-page: 374 ident: bib12 article-title: Measurement of metabolic fluxes using stable isotope tracers in whole animals and human patients publication-title: Curr Opin Clin Nutr Metab Care. – volume: 28 start-page: 1221 year: 1987 end-page: 1227 ident: bib119 article-title: Short chain fatty acids in human large intestine, portal, hepatic and venous blood publication-title: Gut. – volume: 13 start-page: 591 year: 1983 end-page: 593 ident: bib110 article-title: Rapid intubation of the ileo-colonic region of man publication-title: Aust NZ J Med. – volume: 19 start-page: 213 year: 1979 end-page: 217 ident: bib5 article-title: Absorption of elemental and complex nutritional solutions during a continuous jejunal perfusion in man publication-title: Digestion. – volume: 82 start-page: 149 year: 2012 end-page: 155 ident: bib87 article-title: The effect of erythromycin on gastrointestinal motility in subtotal gastrectomized patients publication-title: J Korean Surg Soc. – volume: 35 start-page: 1747 year: 1994 end-page: 1752 ident: bib105 article-title: Digestibility and bulking effect of ispaghula husks in healthy humans publication-title: Gut. – volume: 106 start-page: 725 year: 2017 end-page: 735 ident: bib58 article-title: Duodenal and ileal glucose infusions differentially alter gastrointestinal peptides, appetite response, and food intake: a tube feeding study publication-title: Am J Clin Nutr. – volume: 150 start-page: 38 year: 2008 end-page: 42 ident: bib60 article-title: Effects of mid-jejunal compared to duodenal glucose infusion on peptide hormone release and appetite in healthy men publication-title: Regul Pept. – volume: 2018 start-page: 1671483 year: 2018 ident: bib64 article-title: Erythromycin for promoting the postpyloric placement of feeding tubes: a systematic review and meta-analysis publication-title: Gastroenterol Res Pract. – volume: 4 start-page: e00126 year: 2019 ident: bib20 article-title: Spatial and temporal analysis of the stomach and small-intestinal microbiota in fasted healthy humans publication-title: mSphere. – volume: 36 start-page: 143 year: 2017 end-page: 149 ident: bib11 article-title: Intraileal casein infusion increases plasma concentrations of amino acids in humans: a randomized cross over trial publication-title: Clin Nutr. – volume: 25 start-page: 242 year: 2006 end-page: 249 ident: bib68 article-title: Gene expression in human small intestinal mucosa in vivo is mediated by iron-induced oxidative stress publication-title: Physiol Genomics. – volume: 18 start-page: 742 year: 2001 end-page: 744 ident: bib41 article-title: Human jejunal permeability of two polar drugs: cimetidine and ranitidine publication-title: Pharm Res. – volume: 92 start-page: 515 year: 2010 end-page: 524 ident: bib47 article-title: Gastrointestinal metabolism of a vegetable-oil emulsion in healthy subjects publication-title: Am J Clin Nutr. – volume: 74 start-page: 237 year: 2011 end-page: 238 ident: bib82 article-title: Excessive length of a tube in the stomach: a risk factor for a tangled or knotted tube publication-title: Gastrointest Endosc. – volume: 58 start-page: 1079 year: 2010 end-page: 1089 ident: bib26 article-title: Characterization of fasted-state human intestinal fluids collected from duodenum and jejunum publication-title: J Pharm Pharmacol. – volume: 23 start-page: 176 year: 2008 end-page: 181 ident: bib69 article-title: Transnasal endoscopic placement of nasoenteric feeding tubes: outcomes and limitations in non–critically ill patients publication-title: Nutr Clin Pract. – volume: 85 start-page: e410 year: 2012 end-page: e415 ident: bib93 article-title: Laxative-free CT colonography publication-title: Br J Radiol. – volume: 341 start-page: 134 year: 2007 end-page: 142 ident: bib53 article-title: Pharmacokinetics of gefitinib in humans: the influence of gastrointestinal factors publication-title: Int J Pharm. – volume: 6 start-page: 1415 year: 2012 end-page: 1426 ident: bib122 article-title: The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates publication-title: ISME J. – volume: 102 start-page: 157 year: 2004 end-page: 163 ident: bib120 article-title: Diagnosis of gastrointestinal tract lesions by endoscopic ultrasound-guided fine-needle aspiration biopsy publication-title: Cancer. – volume: 25 start-page: 936 year: 1984 end-page: 941 ident: bib4 article-title: Effect of pectin on jejunal glucose absorption and unstirred layer thickness in normal man publication-title: Gut. – volume: 57 start-page: 987 year: 2010 end-page: 995 ident: bib27 article-title: Determination of intraluminal theophylline concentrations after oral intake of an immediate- and a slow-release dosage form publication-title: J Pharm Pharmacol. – volume: 70 start-page: 217 year: 2001 end-page: 227 ident: bib52 article-title: Determination of in vivo absorption, metabolism, and transport of drugs by the human intestinal wall and liver with a novel perfusion technique publication-title: Clin Pharmacol Ther. – reference: [Internet]. National Library of Medicine (US). Identifier NCT04013607, Fiber Fermentation Kinetics Inside the Gut, and Utilization of Bacterial Metabolites; July 10, 2019 [cited 15 March 2020]. Available from: – volume: 98 start-page: 2163 year: 2005 end-page: 2168 ident: bib61 article-title: Effect of glutamine on water and sodium absorption in human jejunum at baseline and during PGE1-induced secretion publication-title: J Appl Physiol. – volume: 24 start-page: 240 year: 2000 end-page: 243 ident: bib62 article-title: Spontaneous transpyloric migration of a ballooned nasojejunal tube: a randomized controlled trial publication-title: JPEN J Parenter Enteral Nutr. – volume: 157 start-page: 1081 year: 2019 end-page: 1092 ident: bib9 article-title: Analysis of transcriptionally active bacteria throughout the gastrointestinal tract of healthy individuals publication-title: Gastroenterology. – reference: . – volume: 14 start-page: 715 year: 2008 end-page: 719 ident: bib126 article-title: The study of a remote-controlled gastrointestinal drug delivery and sampling system publication-title: Telemed J E Health. – volume: 50 start-page: 1 year: 1966 end-page: 7 ident: bib44 article-title: A method for studying absorption of water and solute from the human small intestine publication-title: Gastroenterology. – volume: 14 start-page: e1002533 year: 2016 ident: bib111 article-title: Revised estimates for the number of human and bacteria cells in the body publication-title: PLoS Biol. – volume: 72 start-page: 954 issue: 4 year: 2000 ident: 10.1093/ajcn/nqab149_bib29 article-title: Postprandial modulation of dietary and whole-body nitrogen utilization by carbohydrates in humans publication-title: Am J Clin Nutr. doi: 10.1093/ajcn/72.4.954 – volume: 31 start-page: 535 issue: 4 year: 2012 ident: 10.1093/ajcn/nqab149_bib34 article-title: The effect of lipid droplet size on satiety and peptide secretion is intestinal site-specific publication-title: Clin Nutr. doi: 10.1016/j.clnu.2011.12.003 – volume: 9 start-page: 176 issue: 2 year: 1973 ident: 10.1093/ajcn/nqab149_bib45 article-title: The method of intraluminal perfusion of the human small intestine. I. Principle and technique publication-title: Digestion. doi: 10.1159/000197443 – volume: 9 start-page: 271 issue: 5 year: 2012 ident: 10.1093/ajcn/nqab149_bib63 article-title: The migrating motor complex: control mechanisms and its role in health and disease publication-title: Nat Rev Gastroenterol Hepatol. doi: 10.1038/nrgastro.2012.57 – volume: 35 start-page: 264 issue: 4 year: 2008 ident: 10.1093/ajcn/nqab149_bib33 article-title: Presystemic elimination of budesonide in man when administered locally at different levels in the gut, with and without local inhibition by ketoconazole publication-title: Eur J Pharm Sci. doi: 10.1016/j.ejps.2008.07.005 – volume: 67 start-page: 4939 issue: 10 year: 2001 ident: 10.1093/ajcn/nqab149_bib37 article-title: Comparative study of bacterial groups within the human cecal and fecal microbiota publication-title: Appl Environ Microbiol. doi: 10.1128/AEM.67.10.4939-4942.2001 – volume: 137 start-page: 594 issue: 3 year: 2007 ident: 10.1093/ajcn/nqab149_bib89 article-title: The poor digestibility of rapeseed protein is balanced by its very high metabolic utilization in humans publication-title: J Nutr. doi: 10.1093/jn/137.3.594 – volume: 5 start-page: e156 year: 2015 ident: 10.1093/ajcn/nqab149_bib40 article-title: Comparative effect of intraduodenal and intrajejunal glucose infusion on the gut-incretin axis response in healthy males publication-title: Nutr Diabetes. doi: 10.1038/nutd.2015.6 – volume: 81 start-page: e370 issue: 3 year: 2012 ident: 10.1093/ajcn/nqab149_bib81 article-title: Magnesium sulfate as an oral contrast medium in magnetic resonance imaging of the small intestine publication-title: Eur J Radiol. doi: 10.1016/j.ejrad.2011.11.049 – volume: 105 start-page: 2904 issue: 9 year: 2016 ident: 10.1093/ajcn/nqab149_bib96 article-title: Gastrointestinal and systemic monitoring of posaconazole in humans after fasted and fed state administration of a solid dispersion publication-title: J Pharm Sci. doi: 10.1016/j.xphs.2016.03.027 – volume: 15 start-page: 271 issue: 3 year: 2002 ident: 10.1093/ajcn/nqab149_bib48 article-title: The effect of amiloride on the in vivo effective permeability of amoxicillin in human jejunum: experience from a regional perfusion technique publication-title: Eur J Pharm Sci. doi: 10.1016/S0928-0987(02)00005-2 – volume: 130 start-page: 2073 issue: 22 year: 2016 ident: 10.1093/ajcn/nqab149_bib112 article-title: Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men publication-title: Clin Sci. doi: 10.1042/CS20160263 – volume: 13 start-page: 3013 issue: 9 year: 2016 ident: 10.1093/ajcn/nqab149_bib31 article-title: Regional intestinal permeability of three model drugs in human publication-title: Mol Pharm. doi: 10.1021/acs.molpharmaceut.6b00514 – volume: 59 start-page: 1373 issue: 12 year: 2005 ident: 10.1093/ajcn/nqab149_bib57 article-title: New strategy to ease the discomfort of insertion of nasogastric tubes publication-title: Int J Clin Pract. doi: 10.1111/j.1368-5031.2005.00751b.x – volume: 288 start-page: G994 issue: 5 year: 2005 ident: 10.1093/ajcn/nqab149_bib90 article-title: Validation of lactose[15N,15N]ureide as a tool to study colonic nitrogen metabolism publication-title: Am J Physiol Gastrointest Liver Physiol. doi: 10.1152/ajpgi.00408.2004 – volume: 21 start-page: 640 issue: 3 year: 2019 ident: 10.1093/ajcn/nqab149_bib16 article-title: Comparative effects of proximal and distal small intestinal administration of metformin on plasma glucose and glucagon-like peptide-1, and gastric emptying after oral glucose, in type 2 diabetes publication-title: Diabetes Obes Metab. doi: 10.1111/dom.13567 – volume: 29 start-page: 276 issue: 5 year: 1980 ident: 10.1093/ajcn/nqab149_bib103 article-title: Effects of diet temperature on tolerance of enteral feedings publication-title: Nurs Res. doi: 10.1097/00006199-198009000-00003 – volume: 14 start-page: 157 issue: 3 year: 1999 ident: 10.1093/ajcn/nqab149_bib101 article-title: Effects of nasogastric tubes on the young, normal swallowing mechanism publication-title: Dysphagia. doi: 10.1007/PL00009598 – volume: 70 start-page: 1002 issue: 8 year: 2018 ident: 10.1093/ajcn/nqab149_bib8 article-title: Intestinal disposition of quercetin and its phase-II metabolites after oral administration in healthy volunteers publication-title: J Pharm Pharmacol. doi: 10.1111/jphp.12929 – volume: 27 start-page: 63 issue: 1 year: 2015 ident: 10.1093/ajcn/nqab149_bib88 article-title: Endogenous motilin, but not ghrelin plasma levels fluctuate in accordance with gastric phase III activity of the migrating motor complex in man publication-title: Neurogastroenterol Motil. doi: 10.1111/nmo.12470 – volume: 15 start-page: 1 issue: 1 year: 2017 ident: 10.1093/ajcn/nqab149_bib7 article-title: Influence of diet on the gut microbiome and implications for human health publication-title: J Transl Med. doi: 10.1186/s12967-017-1175-y – volume: 145 start-page: 2033 issue: 9 year: 2015 ident: 10.1093/ajcn/nqab149_bib2 article-title: Jejunal casein feeding is followed by more rapid protein digestion and amino acid absorption when compared with gastric feeding in healthy young men publication-title: J Nutr. doi: 10.3945/jn.115.211615 – volume: 71 start-page: 77 year: 2014 ident: 10.1093/ajcn/nqab149_bib125 article-title: A review of drug delivery systems for capsule endoscopy publication-title: Adv Drug Deliv Rev. doi: 10.1016/j.addr.2013.12.007 – volume: 19 start-page: 213 issue: 3 year: 1979 ident: 10.1093/ajcn/nqab149_bib5 article-title: Absorption of elemental and complex nutritional solutions during a continuous jejunal perfusion in man publication-title: Digestion. doi: 10.1159/000198347 – volume: 150 start-page: 38 issue: 1–3 year: 2008 ident: 10.1093/ajcn/nqab149_bib60 article-title: Effects of mid-jejunal compared to duodenal glucose infusion on peptide hormone release and appetite in healthy men publication-title: Regul Pept. doi: 10.1016/j.regpep.2008.02.006 – volume: 68 start-page: 363 issue: 3 year: 2014 ident: 10.1093/ajcn/nqab149_bib73 article-title: Endogenous proteins in the ileal digesta of adult humans given casein-, enzyme-hydrolyzed casein- or crystalline amino-acid-based diets in an acute feeding study publication-title: Eur J Clin Nutr. doi: 10.1038/ejcn.2013.270 – volume: 108 start-page: 1620 issue: 10 year: 2013 ident: 10.1093/ajcn/nqab149_bib18 article-title: Temporal bacterial community dynamics vary among ulcerative colitis patients after fecal microbiota transplantation publication-title: Am J Gastroenterol. doi: 10.1038/ajg.2013.257 – volume: 2018 start-page: 1671483 year: 2018 ident: 10.1093/ajcn/nqab149_bib64 article-title: Erythromycin for promoting the postpyloric placement of feeding tubes: a systematic review and meta-analysis publication-title: Gastroenterol Res Pract. doi: 10.1155/2018/1671483 – volume: 157 start-page: 1081 issue: 4 year: 2019 ident: 10.1093/ajcn/nqab149_bib9 article-title: Analysis of transcriptionally active bacteria throughout the gastrointestinal tract of healthy individuals publication-title: Gastroenterology. doi: 10.1053/j.gastro.2019.05.068 – volume: 299 start-page: G1276 issue: 6 year: 2010 ident: 10.1093/ajcn/nqab149_bib66 article-title: Accurate localization of a fall in pH within the ileocecal region: validation using a dual-scintigraphic technique publication-title: Am J Physiol Gastrointest Liver Physiol. doi: 10.1152/ajpgi.00127.2010 – volume: 81 start-page: 87 issue: 1 year: 2005 ident: 10.1093/ajcn/nqab149_bib78 article-title: Postprandial metabolic utilization of wheat protein in humans publication-title: Am J Clin Nutr. doi: 10.1093/ajcn/81.1.87 – volume: 14 start-page: 715 issue: 7 year: 2008 ident: 10.1093/ajcn/nqab149_bib126 article-title: The study of a remote-controlled gastrointestinal drug delivery and sampling system publication-title: Telemed J E Health. doi: 10.1089/tmj.2007.0118 – volume: 76 start-page: 230 issue: 3 year: 2004 ident: 10.1093/ajcn/nqab149_bib49 article-title: Impact of concentration and rate of intraluminal drug delivery on absorption and gut wall metabolism of verapamil in humans publication-title: Clin Pharmacol Ther. doi: 10.1016/j.clpt.2004.04.013 – volume: 44 start-page: 599 issue: 6 year: 2004 ident: 10.1093/ajcn/nqab149_bib92 article-title: Absorption of rivastigmine from different regions of the gastrointestinal tract in humans publication-title: J Clin Pharmacol. doi: 10.1177/0091270004265645 – volume: 57 start-page: 987 issue: 8 year: 2010 ident: 10.1093/ajcn/nqab149_bib27 article-title: Determination of intraluminal theophylline concentrations after oral intake of an immediate- and a slow-release dosage form publication-title: J Pharm Pharmacol. doi: 10.1211/0022357056631 – volume: 341 start-page: 134 issue: 1-2 year: 2007 ident: 10.1093/ajcn/nqab149_bib53 article-title: Pharmacokinetics of gefitinib in humans: the influence of gastrointestinal factors publication-title: Int J Pharm. doi: 10.1016/j.ijpharm.2007.04.002 – volume: 148 start-page: 764 issue: 6 year: 2006 ident: 10.1093/ajcn/nqab149_bib19 article-title: Understanding intestinal cysteamine bitartrate absorption publication-title: J Pediatr. doi: 10.1016/j.jpeds.2006.01.050 – volume: 46 start-page: 393 issue: 3 year: 1974 ident: 10.1093/ajcn/nqab149_bib6 article-title: Absorption of two tripeptides by the human small intestine: A study using a perfusion technique publication-title: Clin Sci Mol Med. – volume: 51 start-page: 110 issue: 1 year: 2010 ident: 10.1093/ajcn/nqab149_bib25 article-title: Practical approach to paediatric enteral nutrition: a comment by the ESPGHAN Committee on Nutrition publication-title: J Pediatr Gastroenterol Nutr. doi: 10.1097/MPG.0b013e3181d336d2 – volume: 7 start-page: 13100 issue: 1 year: 2017 ident: 10.1093/ajcn/nqab149_bib97 article-title: Randomized clinical trial: effective gluten degradation by Aspergillus niger-derived enzyme in a complex meal setting publication-title: Sci Rep. doi: 10.1038/s41598-017-13587-7 – volume: 39 start-page: 235 issue: 2 year: 2015 ident: 10.1093/ajcn/nqab149_bib14 article-title: Ileal brake activation: macronutrient-specific effects on eating behavior? publication-title: Int J Obes. doi: 10.1038/ijo.2014.112 – volume: 85 start-page: e410 issue: 1016 year: 2012 ident: 10.1093/ajcn/nqab149_bib93 article-title: Laxative-free CT colonography publication-title: Br J Radiol. doi: 10.1259/bjr/54736800 – volume: 50 start-page: 1 issue: 1 year: 1966 ident: 10.1093/ajcn/nqab149_bib44 article-title: A method for studying absorption of water and solute from the human small intestine publication-title: Gastroenterology. doi: 10.1016/S0016-5085(66)80093-8 – volume: 41 start-page: 217 issue: 2 year: 2017 ident: 10.1093/ajcn/nqab149_bib24 article-title: Small intestinal protein infusion in humans: evidence for a location-specific gradient in intestinal feedback on food intake and GI peptide release publication-title: Int J Obes. doi: 10.1038/ijo.2016.196 – volume: 103 start-page: 72 issue: 1 year: 1992 ident: 10.1093/ajcn/nqab149_bib85 article-title: Effect of erythromycin on gastric motility in controls and in diabetic gastroparesis publication-title: Gastroenterology. doi: 10.1016/0016-5085(92)91097-N – volume: 2 start-page: 236 issue: 5 year: 1957 ident: 10.1093/ajcn/nqab149_bib117 article-title: Intraluminal biopsy of the small intestine; The intestinal biopsy capsule publication-title: Am J Dig Dis. doi: 10.1007/BF02231100 – volume: 82 start-page: 149 issue: 3 year: 2012 ident: 10.1093/ajcn/nqab149_bib87 article-title: The effect of erythromycin on gastrointestinal motility in subtotal gastrectomized patients publication-title: J Korean Surg Soc. doi: 10.4174/jkss.2012.82.3.149 – volume: 14 start-page: 823 issue: 6 year: 2000 ident: 10.1093/ajcn/nqab149_bib38 article-title: Pharmacokinetics of Lactobacillus plantarum NCIMB 8826, Lactobacillus fermentum KLD, and Lactococcus lactis MG 1363 in the human gastrointestinal tract publication-title: Aliment Pharmacol Ther. doi: 10.1046/j.1365-2036.2000.00763.x – volume: 23 start-page: 742 issue: 4 year: 2006 ident: 10.1093/ajcn/nqab149_bib54 article-title: A clinical single-pass perfusion investigation of the dynamic in vivo secretory response to a dietary meal in human proximal small intestine publication-title: Pharm Res. doi: 10.1007/s11095-006-9607-z – volume: 131 start-page: 1706 issue: 6 year: 2001 ident: 10.1093/ajcn/nqab149_bib28 article-title: The influence of the albumin fraction on the bioavailability and postprandial utilization of pea protein given selectively to humans publication-title: J Nutr. doi: 10.1093/jn/131.6.1706 – volume: 74 start-page: 237 issue: 1 year: 2011 ident: 10.1093/ajcn/nqab149_bib82 article-title: Excessive length of a tube in the stomach: a risk factor for a tangled or knotted tube publication-title: Gastrointest Endosc. doi: 10.1016/j.gie.2011.03.001 – volume: 35 start-page: 1747 issue: 12 year: 1994 ident: 10.1093/ajcn/nqab149_bib105 article-title: Digestibility and bulking effect of ispaghula husks in healthy humans publication-title: Gut. doi: 10.1136/gut.35.12.1747 – volume: 14 start-page: e1002533 issue: 8 year: 2016 ident: 10.1093/ajcn/nqab149_bib111 article-title: Revised estimates for the number of human and bacteria cells in the body publication-title: PLoS Biol. doi: 10.1371/journal.pbio.1002533 – volume: 30 start-page: 448 issue: 05 year: 1998 ident: 10.1093/ajcn/nqab149_bib55 article-title: Transnasal gastroscopy compared to conventional gastroscopy: a randomized study of feasibility, safety, and tolerance publication-title: Endoscopy. doi: 10.1055/s-2007-1001306 – volume: 145 start-page: 2221 issue: 10 year: 2015 ident: 10.1093/ajcn/nqab149_bib39 article-title: High true ileal digestibility but not postprandial utilization of nitrogen from bovine meat protein in humans is moderately decreased by high-temperature, long-duration cooking publication-title: J Nutr. doi: 10.3945/jn.115.216838 – volume: 30 start-page: 275 issue: 3 year: 2015 ident: 10.1093/ajcn/nqab149_bib70 article-title: Electromagnetic sensor-guided enteral access systems: a literature review publication-title: Dysphagia. doi: 10.1007/s00455-015-9607-4 – volume: 12 start-page: 109 issue: 2 year: 2018 ident: 10.1093/ajcn/nqab149_bib118 article-title: Non-endoscopic biopsy techniques: a review publication-title: Expert Rev Gastroenterol Hepatol. doi: 10.1080/17474124.2018.1412828 – volume: 106 start-page: 1609 issue: 10 year: 2011 ident: 10.1093/ajcn/nqab149_bib35 article-title: Length and site of the small intestine exposed to fat influences hunger and food intake publication-title: Br J Nutr. doi: 10.1017/S0007114511002054 – volume: 28 start-page: 1221 issue: 10 year: 1987 ident: 10.1093/ajcn/nqab149_bib119 article-title: Short chain fatty acids in human large intestine, portal, hepatic and venous blood publication-title: Gut. doi: 10.1136/gut.28.10.1221 – volume: 58 start-page: 1079 issue: 8 year: 2010 ident: 10.1093/ajcn/nqab149_bib26 article-title: Characterization of fasted-state human intestinal fluids collected from duodenum and jejunum publication-title: J Pharm Pharmacol. doi: 10.1211/jpp.58.8.0009 – volume: 102 start-page: 791 issue: 4 year: 2015 ident: 10.1093/ajcn/nqab149_bib121 article-title: Manipulation of starch bioaccessibility in wheat endosperm to regulate starch digestion, postprandial glycemia, insulinemia, and gut hormone responses: a randomized controlled trial in healthy ileostomy participants publication-title: Am J Clin Nutr. doi: 10.3945/ajcn.114.106203 – volume: 10 start-page: 4252 issue: 11 year: 2013 ident: 10.1093/ajcn/nqab149_bib46 article-title: Combined in vitro–in vivo approach to assess the hepatobiliary disposition of a novel oral thrombin inhibitor publication-title: Mol Pharm. doi: 10.1021/mp400341t – volume: 285 start-page: G354 issue: 2 year: 2003 ident: 10.1093/ajcn/nqab149_bib15 article-title: New method to study oxidative damage and antioxidants in the human small bowel: effects of iron application publication-title: Am J Physiol Gastrointest Liver Physiol. doi: 10.1152/ajpgi.00422.2002 – volume: 20 start-page: 366 issue: 5 year: 2017 ident: 10.1093/ajcn/nqab149_bib12 article-title: Measurement of metabolic fluxes using stable isotope tracers in whole animals and human patients publication-title: Curr Opin Clin Nutr Metab Care. doi: 10.1097/MCO.0000000000000393 – volume: 24 start-page: 290 issue: 5 year: 2002 ident: 10.1093/ajcn/nqab149_bib94 article-title: Anatomical study of the length of the human intestine publication-title: Surg Radiol Anat. doi: 10.1007/s00276-002-0057-y – volume: 106 start-page: 725 issue: 3 year: 2017 ident: 10.1093/ajcn/nqab149_bib58 article-title: Duodenal and ileal glucose infusions differentially alter gastrointestinal peptides, appetite response, and food intake: a tube feeding study publication-title: Am J Clin Nutr. doi: 10.3945/ajcn.117.157248 – volume: 62 start-page: 47 issue: 1 year: 2007 ident: 10.1093/ajcn/nqab149_bib30 article-title: Digestive tract microbiota in healthy volunteers publication-title: Clinics. doi: 10.1590/S1807-59322007000100008 – volume: 62 start-page: 353 issue: 4 year: 2007 ident: 10.1093/ajcn/nqab149_bib80 article-title: Small bowel faeces sign in patients without small bowel obstruction publication-title: Clin Radiol. doi: 10.1016/j.crad.2006.11.007 – volume: 38 start-page: 1026 issue: 6 year: 1993 ident: 10.1093/ajcn/nqab149_bib86 article-title: Effect of erythromycin derivative EM523L on human interdigestive gastrointestinal tract publication-title: Dig Dis Sci. doi: 10.1007/BF01295717 – volume: 4 start-page: e00126 issue: 2 year: 2019 ident: 10.1093/ajcn/nqab149_bib20 article-title: Spatial and temporal analysis of the stomach and small-intestinal microbiota in fasted healthy humans publication-title: mSphere. doi: 10.1128/mSphere.00126-19 – volume: 28 start-page: 914 issue: S1 year: 2014 ident: 10.1093/ajcn/nqab149_bib95 article-title: Human intestinal tract length and relationship with body height publication-title: FASEB J. doi: 10.1096/fasebj.28.1_supplement.916.4 – volume: 98 start-page: E718 issue: 4 year: 2013 ident: 10.1093/ajcn/nqab149_bib43 article-title: Effects of taurocholic acid on glycemic, glucagon-like peptide-1, and insulin responses to small intestinal glucose infusion in healthy humans publication-title: J Clin Endocrinol Metab. doi: 10.1210/jc.2012-3961 – volume: 53 start-page: 1225 issue: 6 year: 2015 ident: 10.1093/ajcn/nqab149_bib79 article-title: Bowel obstruction publication-title: Radiol Clin North Am. doi: 10.1016/j.rcl.2015.06.008 – volume: 8 start-page: 258 year: 2019 ident: 10.1093/ajcn/nqab149_bib71 article-title: A study protocol for a randomised crossover study evaluating the effect of diets differing in carbohydrate quality on ileal content and appetite regulation in healthy humans publication-title: F1000Res. doi: 10.12688/f1000research.17870.2 – volume: 18 start-page: 1 issue: 1 year: 2018 ident: 10.1093/ajcn/nqab149_bib98 article-title: A novel quick transendoscopic enteral tubing in mid-gut: technique and training with video publication-title: BMC Gastroenterol. doi: 10.1186/s12876-018-0766-2 – volume: 49 start-page: 109 issue: 1 year: 2006 ident: 10.1093/ajcn/nqab149_bib114 article-title: Morphologic alterations associated with mechanical bowel preparation before elective colorectal surgery: a randomized trial publication-title: Dis Colon Rectum. doi: 10.1007/s10350-005-0215-5 – volume: 73 start-page: 223 issue: 3 year: 2003 ident: 10.1093/ajcn/nqab149_bib50 article-title: P-glycoprotein-mediated intestinal and biliary digoxin transport in humans publication-title: Clin Pharmacol Ther. doi: 10.1067/mcp.2003.27 – volume: 71 start-page: 131 issue: 3 year: 2002 ident: 10.1093/ajcn/nqab149_bib51 article-title: Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transporters publication-title: Clin Pharmacol Ther. doi: 10.1067/mcp.2002.121370 – volume: 98 start-page: 2163 issue: 6 year: 2005 ident: 10.1093/ajcn/nqab149_bib61 article-title: Effect of glutamine on water and sodium absorption in human jejunum at baseline and during PGE1-induced secretion publication-title: J Appl Physiol. doi: 10.1152/japplphysiol.00761.2004 – volume: 92 start-page: 515 issue: 3 year: 2010 ident: 10.1093/ajcn/nqab149_bib47 article-title: Gastrointestinal metabolism of a vegetable-oil emulsion in healthy subjects publication-title: Am J Clin Nutr. doi: 10.3945/ajcn.2009.28941 – volume: 4 start-page: 742 issue: 11 year: 1937 ident: 10.1093/ajcn/nqab149_bib102 article-title: Intubation studies of the human small intestine: VII. Factors concerned in absorption of glucose from the jejunum and ileum publication-title: Am J Dig Dis. doi: 10.1007/BF03000444 – volume: 84 start-page: 1568 issue: 6 year: 1983 ident: 10.1093/ajcn/nqab149_bib109 article-title: Effect of gastrointestinal intubation on the passage of a solid meal through the stomach and small intestine in humans publication-title: Gastroenterology. doi: 10.1016/0016-5085(83)90382-7 – volume: 10 issue: 151 year: 2020 ident: 10.1093/ajcn/nqab149_bib127 article-title: Current sampling methods for gut microbiota: a call for more precise devices publication-title: Front Cell Infect Microbiol. – volume: 90 start-page: 1804 issue: 10 year: 1995 ident: 10.1093/ajcn/nqab149_bib23 article-title: The effect of nasogastric intubation on gastroesophageal reflux: a comparison of different tube sizes publication-title: Am J Gastroenterol. – volume: 32 start-page: 1633 issue: 11 year: 2008 ident: 10.1093/ajcn/nqab149_bib77 article-title: Effect of ileal fat perfusion on satiety and hormone release in healthy volunteers publication-title: Int J Obes. doi: 10.1038/ijo.2008.166 – volume: 84 start-page: 1027 issue: 9 year: 1989 ident: 10.1093/ajcn/nqab149_bib113 article-title: Effect of rectal infusion of short chain fatty acids in human subjects publication-title: Am J Gastroenterol. – volume: 11 start-page: e0167775 issue: 12 year: 2016 ident: 10.1093/ajcn/nqab149_bib13 article-title: Effects of supplementation of the synbiotic ecologic(R) 825/FOS P6 on intestinal barrier function in healthy humans: a randomized controlled trial publication-title: PLoS One. doi: 10.1371/journal.pone.0167775 – volume: 282 start-page: G1009 issue: 6 year: 2002 ident: 10.1093/ajcn/nqab149_bib65 article-title: Micellar distribution of cholesterol and phytosterols after duodenal plant stanol ester infusion publication-title: Am J Physiol Gastrointest Liver Physiol. doi: 10.1152/ajpgi.00446.2001 – volume: 96 start-page: 508 issue: 3 year: 2012 ident: 10.1093/ajcn/nqab149_bib76 article-title: Endogenous proteins in terminal ileal digesta of adult subjects fed a casein-based diet publication-title: Am J Clin Nutr. doi: 10.3945/ajcn.111.033472 – volume: 6 start-page: 1415 issue: 7 year: 2012 ident: 10.1093/ajcn/nqab149_bib122 article-title: The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates publication-title: ISME J. doi: 10.1038/ismej.2011.212 – volume: 89 start-page: 1019 issue: 4 year: 2009 ident: 10.1093/ajcn/nqab149_bib36 article-title: Effect of fat saturation on satiety, hormone release, and food intake publication-title: Am J Clin Nutr. doi: 10.3945/ajcn.2008.27335 – volume: 86 start-page: 126 year: 2016 ident: 10.1093/ajcn/nqab149_bib42 article-title: Regional specificity of the gut-incretin response to small intestinal glucose infusion in healthy older subjects publication-title: Peptides. doi: 10.1016/j.peptides.2016.10.010 – volume: 9 start-page: 33 issue: 1 year: 2020 ident: 10.1093/ajcn/nqab149_bib91 article-title: The structure and function of the human small intestinal microbiota: current understanding and future directions publication-title: Cell Mol Gastroenterol Hepatol. doi: 10.1016/j.jcmgh.2019.07.006 – volume: 23 start-page: 176 issue: 2 year: 2008 ident: 10.1093/ajcn/nqab149_bib69 article-title: Transnasal endoscopic placement of nasoenteric feeding tubes: outcomes and limitations in non–critically ill patients publication-title: Nutr Clin Pract. doi: 10.1177/0884533608314535 – volume: 46 start-page: 530 issue: 5 year: 2012 ident: 10.1093/ajcn/nqab149_bib32 article-title: Differentiating mucosal and hepatic metabolism of budesonide by local pretreatment with increasing doses of ketoconazole in the proximal jejunum publication-title: Eur J Pharm Sci. doi: 10.1016/j.ejps.2012.04.005 – ident: 10.1093/ajcn/nqab149_bib107 – volume: 7 start-page: e143 issue: 2 year: 2016 ident: 10.1093/ajcn/nqab149_bib115 article-title: The effects of bowel preparation on microbiota-related metrics differ in health and in inflammatory bowel disease and for the mucosal and luminal microbiota compartments publication-title: Clin Transl Gastroenterol. doi: 10.1038/ctg.2015.54 – volume: 24 start-page: 240 issue: 4 year: 2000 ident: 10.1093/ajcn/nqab149_bib62 article-title: Spontaneous transpyloric migration of a ballooned nasojejunal tube: a randomized controlled trial publication-title: JPEN J Parenter Enteral Nutr. doi: 10.1177/0148607100024004240 – volume: 111 start-page: 90 issue: 1 year: 2020 ident: 10.1093/ajcn/nqab149_bib75 article-title: Intact and hydrolyzed casein lead to similar ileal endogenous protein and amino acid flows in adult humans publication-title: Am J Clin Nutr. doi: 10.1093/ajcn/nqz268 – volume: 53 start-page: 14 issue: 1 year: 2001 ident: 10.1093/ajcn/nqab149_bib56 article-title: Evaluation of topical pharyngeal anesthesia for upper endoscopy including factors associated with patient tolerance publication-title: Gastrointest Endosc. doi: 10.1067/mge.2001.111773 – volume: 54 start-page: 660 issue: 8 year: 2008 ident: 10.1093/ajcn/nqab149_bib74 article-title: Modulation of Lactobacillus casei in ileal and fecal samples from healthy volunteers after consumption of a fermented milk containing Lactobacillus casei DN-114 001Rif publication-title: Can J Microbiol. doi: 10.1139/W08-050 – volume: 55 start-page: 19 issue: Suppl 1 year: 1979 ident: 10.1093/ajcn/nqab149_bib84 article-title: Effects of intravenous and oral domperidone on the motor function of the stomach and small intestine publication-title: Postgrad Med J. – volume: 18 start-page: 742 issue: 6 year: 2001 ident: 10.1093/ajcn/nqab149_bib41 article-title: Human jejunal permeability of two polar drugs: cimetidine and ranitidine publication-title: Pharm Res. doi: 10.1023/A:1011020025338 – volume: 45 start-page: 1601 issue: 8 year: 2000 ident: 10.1093/ajcn/nqab149_bib72 article-title: Sequential group trial to determine gastrointestinal site of absorption and systemic exposure of azathioprine publication-title: Dig Dis Sci. doi: 10.1023/A:1005573229786 – volume: 35 start-page: 1965 issue: 11 year: 2018 ident: 10.1093/ajcn/nqab149_bib124 article-title: A novel ileocolonic release peppermint oil capsule for treatment of irritable bowel syndrome: a Phase I study in healthy volunteers publication-title: Adv Ther. doi: 10.1007/s12325-018-0802-1 – volume: 36 start-page: 143 issue: 1 year: 2017 ident: 10.1093/ajcn/nqab149_bib11 article-title: Intraileal casein infusion increases plasma concentrations of amino acids in humans: a randomized cross over trial publication-title: Clin Nutr. doi: 10.1016/j.clnu.2016.01.012 – volume: 64 start-page: 1562 issue: 10 year: 2015 ident: 10.1093/ajcn/nqab149_bib116 article-title: Effects of bowel cleansing on the intestinal microbiota publication-title: Gut. doi: 10.1136/gutjnl-2014-307240 – volume: 11 start-page: 472 issue: 2 year: 2019 ident: 10.1093/ajcn/nqab149_bib10 article-title: Intraintestinal delivery of tastants using a naso-duodenal-ileal catheter does not influence food intake or satiety publication-title: Nutrients. doi: 10.3390/nu11020472 – volume: 26 start-page: 253 issue: 4 year: 1998 ident: 10.1093/ajcn/nqab149_bib100 article-title: Factors affecting patient tolerance of upper gastrointestinal endoscopy publication-title: J Clin Gastroenterol. doi: 10.1097/00004836-199806000-00006 – volume: 67 start-page: 202 issue: 2 year: 2013 ident: 10.1093/ajcn/nqab149_bib1 article-title: Double-balloon jejunal perfusion to compare absorption of vitamin E and vitamin E acetate in healthy volunteers under maldigestion conditions publication-title: Eur J Clin Nutr. doi: 10.1038/ejcn.2012.183 – volume: 102 start-page: 157 issue: 3 year: 2004 ident: 10.1093/ajcn/nqab149_bib120 article-title: Diagnosis of gastrointestinal tract lesions by endoscopic ultrasound-guided fine-needle aspiration biopsy publication-title: Cancer. doi: 10.1002/cncr.20360 – volume: 25 start-page: 936 issue: 9 year: 1984 ident: 10.1093/ajcn/nqab149_bib4 article-title: Effect of pectin on jejunal glucose absorption and unstirred layer thickness in normal man publication-title: Gut. doi: 10.1136/gut.25.9.936 – volume: 25 start-page: 242 issue: 2 year: 2006 ident: 10.1093/ajcn/nqab149_bib68 article-title: Gene expression in human small intestinal mucosa in vivo is mediated by iron-induced oxidative stress publication-title: Physiol Genomics. doi: 10.1152/physiolgenomics.00114.2005 – volume: 50 start-page: 69 issue: 1 year: 2000 ident: 10.1093/ajcn/nqab149_bib59 article-title: Absorption of lefradafiban from different sites of the gastrointestinal tract publication-title: Br J Clin Pharmacol. doi: 10.1046/j.1365-2125.2000.00228.x – volume: 101 start-page: 147 issue: 3 year: 2012 ident: 10.1093/ajcn/nqab149_bib99 article-title: Nasoenteric tube complications publication-title: Scand J Surg. doi: 10.1177/145749691210100302 – volume: 595 start-page: 541 issue: 2 year: 2017 ident: 10.1093/ajcn/nqab149_bib123 article-title: Systemic availability and metabolism of colonic-derived short-chain fatty acids in healthy subjects: A stable isotope study publication-title: J Physiol. doi: 10.1113/JP272613 – volume: 47 start-page: 236 issue: 3 year: 2016 ident: 10.1093/ajcn/nqab149_bib17 article-title: Fecal microbiota transplantation in combination with soluble dietary fiber for treatment of slow transit constipation: a pilot study publication-title: Arch Med Res. doi: 10.1016/j.arcmed.2016.06.005 – volume: 1 start-page: 690982 year: 2019 ident: 10.1093/ajcn/nqab149_bib128 article-title: Ingestible osmotic pill for in-vivo sampling of gut microbiome publication-title: BioRxiv. – volume: 13 start-page: 591 issue: 6 year: 1983 ident: 10.1093/ajcn/nqab149_bib110 article-title: Rapid intubation of the ileo-colonic region of man publication-title: Aust NZ J Med. doi: 10.1111/j.1445-5994.1983.tb02610.x – volume: 42 start-page: 1613 issue: 8 year: 1997 ident: 10.1093/ajcn/nqab149_bib22 article-title: Effect of viscous fiber (guar) on postprandial motor activity in human small bowel publication-title: Dig Dis Sci. doi: 10.1023/A:1018888726646 – volume: 70 start-page: 217 issue: 3 year: 2001 ident: 10.1093/ajcn/nqab149_bib52 article-title: Determination of in vivo absorption, metabolism, and transport of drugs by the human intestinal wall and liver with a novel perfusion technique publication-title: Clin Pharmacol Ther. doi: 10.1067/mcp.2001.117937 – volume: 123 start-page: 50 issue: 1 year: 2002 ident: 10.1093/ajcn/nqab149_bib104 article-title: Ileal losses of nitrogen and amino acids in humans and their importance to the assessment of amino acid requirements publication-title: Gastroenterology. doi: 10.1053/gast.2002.34233 – volume: 2 start-page: 155 issue: 5 year: 2010 ident: 10.1093/ajcn/nqab149_bib67 article-title: Endoscopic placement of enteral feeding tubes publication-title: World J Gastrointest Endosc. doi: 10.4253/wjge.v2.i5.155 – ident: 10.1093/ajcn/nqab149_bib21 – volume: 82 start-page: 701 issue: 4 year: 1982 ident: 10.1093/ajcn/nqab149_bib106 article-title: Relationship of motility to flow of contents in the human small intestine publication-title: Gastroenterology. doi: 10.1016/0016-5085(82)90314-6 – volume: 69 start-page: 108 issue: 1 year: 1991 ident: 10.1093/ajcn/nqab149_bib3 article-title: Measurement of starch absorption in humans publication-title: Can J Physiol Pharmacol. doi: 10.1139/y91-015 – volume: 33 start-page: 429 issue: 4 year: 1999 ident: 10.1093/ajcn/nqab149_bib83 article-title: Domperidone: a peripherally acting dopamine2-receptor antagonist publication-title: Ann Pharmacother. doi: 10.1345/aph.18003 – volume: 7 start-page: 468 issue: 11 year: 1940 ident: 10.1093/ajcn/nqab149_bib108 article-title: Intubation studies of the human small intestine publication-title: Am J Dig Dis. doi: 10.1007/BF03000054 |
| SSID | ssj0012486 |
| Score | 2.424208 |
| SecondaryResourceType | review_article |
| Snippet | Intestinal catheters have been used for decades in human nutrition, physiology, pharmacokinetics, and gut microbiome research, facilitating the delivery of... |
| SourceID | swepub pubmedcentral proquest pubmed crossref elsevier |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 843 |
| SubjectTerms | Adverse events Aspiration Balloon treatment Biomedical materials Catheterization - instrumentation Catheterization - methods Catheters Clinical trials Colon delivery Duodenum Fluid dynamics human Human nutrition Humans Ileum In vivo methods and tests intestinal catheter Intestinal microflora Intestine Intestines - physiology Jejunum Medical equipment Medical instruments Medical research Microbiomes Narrative Review Nutrition Pharmacokinetics Research Design Sampling Segments Small intestine trials |
| Title | Using naso- and oro-intestinal catheters in physiological research for intestinal delivery and sampling in vivo: practical and technical aspects to be considered |
| URI | https://dx.doi.org/10.1093/ajcn/nqab149 https://www.ncbi.nlm.nih.gov/pubmed/34036315 https://www.proquest.com/docview/2569411097 https://www.proquest.com/docview/2532258549 https://pubmed.ncbi.nlm.nih.gov/PMC8408849 https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-91945 |
| Volume | 114 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9NAEF61Rap64VFegYIWiXBBJo29fiy3qC0KoFQcUtSbZW_W1FWwS-L0wL_hnzKzrzikQdBDrMT2eh3NY2d2Zr4h5DXoRSkOc-mFPDv0GBN9j0cT4OXcFzzmmcgy3NAfnUbDM_bpPDzf2r7XylpaNPk78fPGupLbUBXOAV2xSvY_KOseCifgO9AXjkBhOP4TjXW8v8rmtaeCAPWs9hD_AcQWjUwFyYromSpVHAniNJ3B-LlQWYatIRM5xUQNDco0zzDdXNe8XJfX-Lq2qsogDGgEWPVLlWwquIhcJcDf0AZ0vKxiqdqQFa46s7KtAZzCHmJf4e6R3x0cjmfl5ZUpL1quJeVU7xWdYEsYFz1S4f_jeu6NEIBAa8KRnFrFp3bg58I0CRhM4K3aux9-36V3NX-rqvxD44MJrCPnUit5Dko-8HW3XbcK6FpWw-5BS6cnGkfKmgcaO35t5dGoXNmlwNW1-pHlfQ3F2mLDq--KDwOGwfN-uFyBXV7kl9ERONxJwvg2ueOD46M2CT5-dnExn6nepe5fmVIOmLyHU_fMxHtk186yyd5a96fW04JXwHOVwTW-T-4aT4kONNs_IFuy2ied41I29A01cLZTempZZp_sjkyeyEPyS0kGVZJBgVHpqmRQJxm0rOiKZFArGRRITltDrGSox1nJwOEoGe-pkwt13ckFNXJBm5rmki7l4hE5-3AyPhp6phmJJxiPGg8cjYizROY-C0WRxaHIc_BGJlEs8jgOi0TIhIUFn6BNHE0CVHZAvwKoEQEHyeAx2anqSj4lNAqiMM4CxqQvwPtnXPRhneWCiSQq_KLokLeWZKkwSP3YMGaa6oyRIEVap4bWHdJ1d19phJoN9_Us9VNjXWurOQUW3jDiwDJJapTCPAUXiTOEKY475JW7DGsSBhqzStYLvAfNhCTERzzRPOVezfJlh8Qr3OZuQLz71StVeaFw741owB_WfLky5Lj8Okjr2Tf4LFLe5yx8dusZnpO9pa45IDvNbCFfgO_R5C-VOP4G9Yo8XQ |
| linkProvider | Flying Publisher |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Using+naso-+and+oro-intestinal+catheters+in+physiological+research+for+intestinal+delivery+and+sampling+in+vivo%3A+practical+and+technical+aspects+to+be+considered&rft.jtitle=The+American+journal+of+clinical+nutrition&rft.au=PH+van%C2%A0Trijp%2C+Mara&rft.au=Wilms%2C+Ellen&rft.au=R%C3%ADos-Morales%2C+Melany&rft.au=Masclee%2C+Ad+Am&rft.date=2021-09-01&rft.pub=Oxford+University+Press&rft.issn=0002-9165&rft.eissn=1938-3207&rft.volume=114&rft.issue=3&rft.spage=843&rft.epage=861&rft_id=info:doi/10.1093%2Fajcn%2Fnqab149&rft_id=info%3Apmid%2F34036315&rft.externalDocID=PMC8408849 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0002-9165&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0002-9165&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0002-9165&client=summon |