MicroRNA-485-5p targets keratin 17 to regulate oral cancer stemness and chemoresistance via the integrin/FAK/Src/ERK/β-catenin pathway - Jang, Te-Hsuan; Huang, Wei-Chieh; Tung, Shiao-Lin; Lin, Sheng-Chieh; Chen, Po-Ming; Cho, Chun-Yu; Yang, Ya-Yu; Yen, Tzu-Chen; Lo, Guo-Hsuen; Chuang, Shuang-En; Wang, Lu-Hai (Journal of biomedical science, 2022)
Keywords: Assaying; Breast cancer; Cancer; Cancer stemness; Cancer therapies; Carboplatin; CD44 antigen; Cell growth; Cell proliferation; Cervical cancer; Chemoresistance; Chemotherapy; Cisplatin; Cloning; Combinatorial analysis; Cytoskeleton; Dasatinib; Drug resistance; Epidermal growth factor; Epidermal growth factor receptors; Esophagus; Evaluation; Extracellular signal-regulated kinase; Focal adhesion kinase; Gene expression; Gene silencing; Growth factors; Growth rate; Integrin β4; Invasiveness; Keratin; Keratin 17; Kinases; Lung cancer; Medical prognosis; Mesenchyme; Metastases; Metastasis; MicroRNAs; miR-485-5p; miRNA; Nuclear transport; Oral cancer; Oral carcinoma; Phosphorylation; Plasmids; Proteins; Radiation therapy; Resistance factors; Review boards; Signal transduction; Signaling; Squamous cell carcinoma; Stem cells; Translocation; Tumor cell lines; Tumorigenesis; Tumors; Xenografts; Xenotransplantation; β-catenin; United States--US; Taiwan; Dasatinib; β-catenin; Keratin 17; Chemoresistance; miR-485-5p; Cancer stemness; Oral squamous cell carcinoma; Integrin β4