Antidepressant-like Effects of p-Coumaric Acid on LPS-induced Depressive and Inflammatory Changes in Rats
Depression causes mental and physical changes which affect quality of life. It is estimated to become the second most prevalent disease, but despite its commonness, the pathophysiology of depression remains unclear and medicine is not sufficiently protective. p-Coumaric acid (p-CA) is a dietary phen...
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Published in | Experimental neurobiology Vol. 27; no. 3; pp. 189 - 199 |
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Main Authors | , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Korea (South)
The Korean Society for Brain and Neural Science
01.06.2018
한국뇌신경과학회 |
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Abstract | Depression causes mental and physical changes which affect quality of life. It is estimated to become the second most prevalent disease, but despite its commonness, the pathophysiology of depression remains unclear and medicine is not sufficiently protective. p-Coumaric acid (p-CA) is a dietary phenolic acid which has been proven to have antifungal, anti-HIV, anti-melanogenic, antioxidant and anti-inflammatory effects. Considering these effects, we investigated whether p-CA can prevent depressive symptoms by reducing inflammatory cytokines in animals injected with lipopolysaccharide (LPS). Changes in despair-related behaviors, inflammatory cytokines, neurotrophic factors and synaptic activity were measured. In these animals, p-CA improved despair-related behavioral symptoms induced by LPS in the forced swim test (FST), tail suspension test (TST) and sucrose splash test (SST). p-CA also prevented the increase of inflammatory cytokines in the hippocampus such as cycloxigenase-2 and tumor necrosis factor-α due to LPS. Similarly, it prevented the reduction of brain-derived neurotrophic factor (BDNF) by LPS. Electrophysiologically, p-CA blocked the reduction of long-term depression in LPS-treated organotypic tissue slices. In conclusion, p-CA prevented LPS-induced depressive symptoms in animals, as determined by behavioral, biochemical and electrophysiological measures. These findings suggest the potential use of p-CA as a preventive and therapeutic medicine for depression. |
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AbstractList | Depression causes mental and physical changes which affect quality of life. It is estimated to become the second most prevalent disease, but despite its commonness, the pathophysiology of depression remains unclear and medicine is not sufficiently protective. p-Coumaric acid (p-CA) is a dietary phenolic acid which has been proven to have antifungal, anti-HIV, anti-melanogenic, antioxidant and anti-inflammatory effects. Considering these effects, we investigated whether p-CA can prevent depressive symptoms by reducing inflammatory cytokines in animals injected with lipopolysaccharide (LPS). Changes in despair-related behaviors, inflammatory cytokines, neurotrophic factors and synaptic activity were measured. In these animals, p-CA improved despair-related behavioral symptoms induced by LPS in the forced swim test (FST), tail suspension test (TST) and sucrose splash test (SST). p-CA also prevented the increase of inflammatory cytokines in the hippocampus such as cycloxigenase-2 and tumor necrosis factor-α due to LPS. Similarly, it prevented the reduction of brain-derived neurotrophic factor (BDNF) by LPS. Electrophysiologically, p-CA blocked the reduction of long-term depression in LPS-treated organotypic tissue slices. In conclusion, p-CA prevented LPS-induced depressive symptoms in animals, as determined by behavioral, biochemical and electrophysiological measures. These findings suggest the potential use of p-CA as a preventive and therapeutic medicine for depression. Depression causes mental and physical changes which affect quality of life. It is estimated to become the second most prevalent disease, but despite its commonness, the pathophysiology of depression remains unclear and medicine is not sufficiently protective. pCoumaric acid (p-CA) is a dietary phenolic acid which has been proven to have antifungal, anti-HIV, anti-melanogenic, antioxidant and anti-inflammatory effects. Considering these effects, we investigated whether p-CA can prevent depressive symptoms by reducing inflammatory cytokines in animals injected with lipopolysaccharide (LPS). Changes in despair-related behaviors, inflammatory cytokines, neurotrophic factors and synaptic activity were measured. In these animals, p-CA improved despair-related behavioral symptoms induced by LPS in the forced swim test (FST), tail suspension test (TST) and sucrose splash test (SST). p-CA also prevented the increase of inflammatory cytokines in the hippocampus such as cycloxigenase-2 and tumor necrosis factor-α due to LPS. Similarly, it prevented the reduction of brain-derived neurotrophic factor (BDNF) by LPS. Electrophysiologically, p-CA blocked the reduction of long-term depression in LPS-treated organotypic tissue slices. In conclusion, p-CA prevented LPS-induced depressive symptoms in animals, as determined by behavioral, biochemical and electrophysiological measures. These findings suggest the potential use of p-CA as a preventive and therapeutic medicine for depression. KCI Citation Count: 4 |
Author | Lee, Seok Song, Min-Cheol Kim, Hyun-Bum Park, Ji-Ho Kim, Sung-Soo Lee, Ji-Seung Maeng, Sungho Kim, Eun-Seok Jeon, Tae-Dong Chung, Min-Chan Hwang, Eun-Sang |
AuthorAffiliation | 2 Department of Gerontology, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea 1 Department of East-West Medical Science, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea 3 Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea 4 Research Institute of Medical Nutrition, Kyung Hee University, Yongin 17104, Korea |
AuthorAffiliation_xml | – name: 1 Department of East-West Medical Science, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea – name: 3 Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea – name: 2 Department of Gerontology, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea – name: 4 Research Institute of Medical Nutrition, Kyung Hee University, Yongin 17104, Korea |
Author_xml | – sequence: 1 givenname: Seok surname: Lee fullname: Lee, Seok organization: Department of East-West Medical Science, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea – sequence: 2 givenname: Hyun-Bum surname: Kim fullname: Kim, Hyun-Bum organization: Department of East-West Medical Science, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea – sequence: 3 givenname: Eun-Sang surname: Hwang fullname: Hwang, Eun-Sang organization: Department of Gerontology, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea – sequence: 4 givenname: Eun-Seok surname: Kim fullname: Kim, Eun-Seok organization: Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea – sequence: 5 givenname: Sung-Soo surname: Kim fullname: Kim, Sung-Soo organization: Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea – sequence: 6 givenname: Tae-Dong surname: Jeon fullname: Jeon, Tae-Dong organization: Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea – sequence: 7 givenname: Min-Cheol surname: Song fullname: Song, Min-Cheol organization: Department of East-West Medical Science, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea – sequence: 8 givenname: Ji-Seung surname: Lee fullname: Lee, Ji-Seung organization: Department of East-West Medical Science, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea – sequence: 9 givenname: Min-Chan surname: Chung fullname: Chung, Min-Chan organization: Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea – sequence: 10 givenname: Sungho surname: Maeng fullname: Maeng, Sungho organization: Department of Gerontology, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea – sequence: 11 givenname: Ji-Ho surname: Park fullname: Park, Ji-Ho organization: Research Institute of Medical Nutrition, Kyung Hee University, Yongin 17104, Korea |
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Cites_doi | 10.1016/j.neuropharm.2012.05.046 10.1016/j.phrs.2017.04.028 10.1016/j.biopsych.2009.09.033 10.1523/JNEUROSCI.2752-13.2014 10.1016/j.pnpbp.2010.04.011 10.1007/s00125-011-2240-3 10.1016/j.bbr.2008.04.021 10.1006/cyto.1997.0238 10.1016/j.pnpbp.2010.08.026 10.4103/2277-9175.188491 10.1016/j.pnpbp.2006.03.025 10.1007/BF02245592 10.5607/en.2015.24.1.71 10.1007/s11011-017-0039-8 10.1002/bies.20658 10.1002/jsfa.7578 10.1001/jamapsychiatry.2013.1111 10.1016/j.jad.2016.06.005 10.1016/j.biopsych.2008.11.029 10.1016/j.bbrc.2018.05.085 10.1016/j.psychres.2017.03.012 10.1016/j.bbi.2011.01.011 10.1016/j.neulet.2015.01.081 10.1002/jbt.21550 10.7603/s40681-015-0021-x 10.1016/j.jpsychires.2015.10.006 10.1016/j.steroids.2015.05.010 10.3892/ijo.2012.1709 10.1016/j.biopsych.2015.04.022 10.1016/S0304-3940(01)02062-6 10.1016/j.pnpbp.2010.06.024 10.1016/j.pnpbp.2013.10.002 10.1016/S0165-5728(98)00199-4 10.1016/j.physbeh.2016.05.017 10.1016/j.bbrc.2017.08.068 10.1016/j.bbrc.2009.03.133 10.1002/syn.21984 10.1097/00006842-200201000-00008 10.1016/0959-4388(94)90101-5 10.1039/C4FO00346B 10.1016/j.neuropharm.2011.08.018 10.1017/S1461145708009309 10.1159/000107420 10.1111/fcp.12252 10.1016/j.bbr.2017.01.008 10.1016/j.chemosphere.2017.09.098 10.1021/acssynbio.6b00081 10.3390/molecules21101341 10.1016/j.neuroscience.2016.11.038 10.1038/sj.mp.4001805 10.1017/neu.2016.68 10.1515/med-2016-0009 10.1038/sj.mp.4002055 |
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Keywords | Long-term synaptic depression (LTD) Depression Cytokines p-coumaric acid (p-CA) Lipopolysaccharide (LPS) |
Language | English |
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References | 19150053 - Biol Psychiatry. 2009 May 1;65(9):732-41 27092814 - ACS Synth Biol. 2016 Jul 15;5(7):741-53 23174888 - Int J Oncol. 2013 Jan;42(1):317-26 24121063 - Prog Neuropsychopharmacol Biol Psychiatry. 2014 Jan 3;48:135-41 20015486 - Biol Psychiatry. 2010 Mar 1;67(5):446-57 27295377 - J Affect Disord. 2016 Oct;203:204-212 23760347 - JAMA Psychiatry. 2013 Aug;70(8):812-20 28830814 - Biochem Biophys Res Commun. 2017 Oct 21;492(3):493-499 24497207 - J Biochem Mol Toxicol. 2014 Apr;28(4):174-80 26615538 - Biomedicine (Taipei). 2015 Dec;5(4):21 29681976 - Evid Based Complement Alternat Med. 2018 Feb 22;2018:5198594 8539342 - Psychopharmacology (Berl). 1995 Sep;121(1):66-72 27862243 - Fundam Clin Pharmacol. 2017 Apr;31(2):226-236 21276847 - Brain Behav Immun. 2011 May;25(4):706-14 18565601 - Behav Brain Res. 2008 Nov 3;193(1):140-3 25098664 - Food Funct. 2014 Oct;5(10):2438-45 29767672 - Am J Hypertens. 2018 May 15;:null 21789690 - Diabetologia. 2011 Oct;54(10):2483-93 28987401 - Chemosphere. 2018 Jan;190:124-134 20406665 - Prog Neuropsychopharmacol Biol Psychiatry. 2011 Apr 29;35(3):722-9 27919695 - Neuroscience. 2017 Feb 20;343:1-9 26692250 - J Sci Food Agric. 2016 Jul;96(9):2952-62 24966374 - J Neurosci. 2014 Jun 25;34(26):8741-8 20828592 - Prog Neuropsychopharmacol Biol Psychiatry. 2011 Apr 29;35(3):744-59 28352765 - Open Med (Wars). 2016 Feb 29;11(1):41-48 11818586 - Psychosom Med. 2002 Jan-Feb;64(1):52-60 26019798 - Iran J Basic Med Sci. 2015 Apr;18(4):356-63 20603175 - Prog Neuropsychopharmacol Biol Psychiatry. 2010 Oct 1;34(7):1223-8 18752720 - Int J Neuropsychopharmacol. 2008 Dec;11(8):1169-80 28573601 - Metab Brain Dis. 2017 Aug;32(4):1279-1286 19341708 - Biochem Biophys Res Commun. 2009 May 22;383(1):93-7 7919934 - Curr Opin Neurobiol. 1994 Jun;4(3):389-99 28062258 - Behav Brain Res. 2017 Mar 30;322(Pt A):138-144 17713352 - Neuroimmunomodulation. 2007;14(2):65-71 16647794 - Prog Neuropsychopharmacol Biol Psychiatry. 2006 Sep 30;30(7):1256-60 9367546 - Cytokine. 1997 Nov;9(11):853-8 26048446 - Steroids. 2015 Sep;101:37-42 22709946 - Neuropharmacology. 2013 Mar;66:339-47 17876779 - Bioessays. 2007 Oct;29(10):957-61 17700577 - Mol Psychiatry. 2008 Jul;13(7):717-28 26037911 - Biol Psychiatry. 2016 May 1;79(9):776-86 29775613 - Biochem Biophys Res Commun. 2018 Jul 2;501(4):933-940 25792871 - Exp Neurobiol. 2015 Mar;24(1):71-83 28465217 - Pharmacol Res. 2017 Jul;121:114-121 27184238 - Physiol Behav. 2016 Sep 1;163:177-183 25650524 - Neurosci Lett. 2015 Mar 17;590:96-100 28481031 - Synapse. 2017 Sep;71(9) 16491133 - Mol Psychiatry. 2006 Jul;11(7):680-4 27754387 - Molecules. 2016 Oct 13;21(10) 26495770 - J Psychiatr Res. 2015 Dec;71:140-7 9916891 - J Neuroimmunol. 1998 Dec 1;92(1-2):160-9 28167853 - Mediators Inflamm. 2017;2017:6280925 11514064 - Neurosci Lett. 2001 Aug 31;309(3):153-6 11444765 - J Clin Psychiatry. 2001;62 Suppl 15:8-11 21867719 - Neuropharmacology. 2012 Jan;62(1):419-26 27938441 - Acta Neuropsychiatr. 2017 Dec;29(6):324-329 28285256 - Psychiatry Res. 2017 Jun;252:270-276 28028518 - Adv Biomed Res. 2016 Nov 28;5:178 Kubera (10.5607/en.2018.27.3.189_ref43) 2011; 35 Li (10.5607/en.2018.27.3.189_ref33) 2016; 21 Pei (10.5607/en.2018.27.3.189_ref45) 2016; 96 Korczak (10.5607/en.2018.27.3.189_ref52) 2011; 54 Sadeghi (10.5607/en.2018.27.3.189_ref28) 2016; 163 Myint (10.5607/en.2018.27.3.189_ref41) 2007; 14 Wang (10.5607/en.2018.27.3.189_ref16) 2018 Min (10.5607/en.2018.27.3.189_ref55) 2009; 383 Motaghinejad (10.5607/en.2018.27.3.189_ref27) 2016; 5 Alcocer-Gómez (10.5607/en.2018.27.3.189_ref7) 2017; 121 Zunszain (10.5607/en.2018.27.3.189_ref30) 2011; 35 Gass (10.5607/en.2018.27.3.189_ref44) 2007; 29 Carl (10.5607/en.2018.27.3.189_ref18) 2016; 203 Li (10.5607/en.2018.27.3.189_ref15) 2018; 501 Ming (10.5607/en.2018.27.3.189_ref14) 2015; 590 Wang (10.5607/en.2018.27.3.189_ref10) 2011; 25 Brachman (10.5607/en.2018.27.3.189_ref37) 2016; 79 Yalcin (10.5607/en.2018.27.3.189_ref36) 2008; 193 Zhou (10.5607/en.2018.27.3.189_ref17) 2017; 343 Kim (10.5607/en.2018.27.3.189_ref22) 2017; 492 Yi (10.5607/en.2018.27.3.189_ref34) 2010; 34 Li (10.5607/en.2018.27.3.189_ref57) 2018; 190 Kim (10.5607/en.2018.27.3.189_ref51) 2015; 24 Kim (10.5607/en.2018.27.3.189_ref31) 2017; 322 Braunstein (10.5607/en.2018.27.3.189_ref2) 2017; 31 Calero (10.5607/en.2018.27.3.189_ref20) 2016; 5 Su (10.5607/en.2018.27.3.189_ref5) 2015; 5 Liu (10.5607/en.2018.27.3.189_ref56) 2014; 34 Cuevas-Olguin (10.5607/en.2018.27.3.189_ref58) 2017; 71 Von Frijtag (10.5607/en.2018.27.3.189_ref19) 2001; 309 Kirkedal (10.5607/en.2018.27.3.189_ref3) 2017; 29 Maes (10.5607/en.2018.27.3.189_ref42) 1997; 9 Goshen (10.5607/en.2018.27.3.189_ref11) 2008; 13 Lavebratt (10.5607/en.2018.27.3.189_ref9) 2017; 252 Detke (10.5607/en.2018.27.3.189_ref26) 1995; 121 Dickens (10.5607/en.2018.27.3.189_ref53) 2002; 64 Reid (10.5607/en.2018.27.3.189_ref6) 2015; 71 Zhu (10.5607/en.2018.27.3.189_ref46) 2018; 2018 Yi (10.5607/en.2018.27.3.189_ref32) 2014; 48 Bear (10.5607/en.2018.27.3.189_ref49) 1994; 4 Hwang (10.5607/en.2018.27.3.189_ref29) 2013; 42 Miller (10.5607/en.2018.27.3.189_ref38) 2009; 65 Müller (10.5607/en.2018.27.3.189_ref40) 2006; 11 Guven (10.5607/en.2018.27.3.189_ref24) 2015; 18 Navaneethan (10.5607/en.2018.27.3.189_ref21) 2014; 5 Kaster (10.5607/en.2018.27.3.189_ref13) 2012; 62 Abdel-Moneim (10.5607/en.2018.27.3.189_ref23) 2017; 32 Ali (10.5607/en.2018.27.3.189_ref35) 2015; 101 Choi (10.5607/en.2018.27.3.189_ref4) 2017; 2017 Talarowska (10.5607/en.2018.27.3.189_ref8) 2016; 11 Pignatelli (10.5607/en.2018.27.3.189_ref50) 2013; 66 Sartorius (10.5607/en.2018.27.3.189_ref1) 2001; 62 Prasanna (10.5607/en.2018.27.3.189_ref25) 2014; 28 Benros (10.5607/en.2018.27.3.189_ref54) 2013; 70 Armario (10.5607/en.2018.27.3.189_ref12) 1998; 92 Dowlati (10.5607/en.2018.27.3.189_ref39) 2010; 67 Aydemir (10.5607/en.2018.27.3.189_ref48) 2006; 30 Brunoni (10.5607/en.2018.27.3.189_ref47) 2008; 11 |
References_xml | – volume: 66 start-page: 339 year: 2013 ident: 10.5607/en.2018.27.3.189_ref50 publication-title: Neuropharmacology doi: 10.1016/j.neuropharm.2012.05.046 contributor: fullname: Pignatelli – volume: 121 start-page: 114 year: 2017 ident: 10.5607/en.2018.27.3.189_ref7 publication-title: Pharmacol Res doi: 10.1016/j.phrs.2017.04.028 contributor: fullname: Alcocer-Gómez – volume: 67 start-page: 446 year: 2010 ident: 10.5607/en.2018.27.3.189_ref39 publication-title: Biol Psychiatry doi: 10.1016/j.biopsych.2009.09.033 contributor: fullname: Dowlati – volume: 34 start-page: 8741 year: 2014 ident: 10.5607/en.2018.27.3.189_ref56 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.2752-13.2014 contributor: fullname: Liu – volume: 35 start-page: 722 year: 2011 ident: 10.5607/en.2018.27.3.189_ref30 publication-title: Prog Neuropsychopharmacol Biol Psychiatry doi: 10.1016/j.pnpbp.2010.04.011 contributor: fullname: Zunszain – volume: 54 start-page: 2483 year: 2011 ident: 10.5607/en.2018.27.3.189_ref52 publication-title: Diabetologia doi: 10.1007/s00125-011-2240-3 contributor: fullname: Korczak – volume: 193 start-page: 140 year: 2008 ident: 10.5607/en.2018.27.3.189_ref36 publication-title: Behav Brain Res doi: 10.1016/j.bbr.2008.04.021 contributor: fullname: Yalcin – volume: 9 start-page: 853 year: 1997 ident: 10.5607/en.2018.27.3.189_ref42 publication-title: Cytokine doi: 10.1006/cyto.1997.0238 contributor: fullname: Maes – volume: 35 start-page: 744 year: 2011 ident: 10.5607/en.2018.27.3.189_ref43 publication-title: Prog Neuropsychopharmacol Biol Psychiatry doi: 10.1016/j.pnpbp.2010.08.026 contributor: fullname: Kubera – volume: 5 start-page: 178 year: 2016 ident: 10.5607/en.2018.27.3.189_ref27 publication-title: Adv Biomed Res doi: 10.4103/2277-9175.188491 contributor: fullname: Motaghinejad – volume: 30 start-page: 1256 year: 2006 ident: 10.5607/en.2018.27.3.189_ref48 publication-title: Prog Neuropsychopharmacol Biol Psychiatry doi: 10.1016/j.pnpbp.2006.03.025 contributor: fullname: Aydemir – volume: 121 start-page: 66 year: 1995 ident: 10.5607/en.2018.27.3.189_ref26 publication-title: Psychopharmacology (Berl) doi: 10.1007/BF02245592 contributor: fullname: Detke – volume: 24 start-page: 71 year: 2015 ident: 10.5607/en.2018.27.3.189_ref51 publication-title: Exp Neurobiol doi: 10.5607/en.2015.24.1.71 contributor: fullname: Kim – volume: 32 start-page: 1279 year: 2017 ident: 10.5607/en.2018.27.3.189_ref23 publication-title: Metab Brain Dis doi: 10.1007/s11011-017-0039-8 contributor: fullname: Abdel-Moneim – volume: 29 start-page: 957 year: 2007 ident: 10.5607/en.2018.27.3.189_ref44 publication-title: BioEssays doi: 10.1002/bies.20658 contributor: fullname: Gass – volume: 96 start-page: 2952 year: 2016 ident: 10.5607/en.2018.27.3.189_ref45 publication-title: J Sci Food Agric doi: 10.1002/jsfa.7578 contributor: fullname: Pei – volume: 70 start-page: 812 year: 2013 ident: 10.5607/en.2018.27.3.189_ref54 publication-title: JAMA Psychiatry doi: 10.1001/jamapsychiatry.2013.1111 contributor: fullname: Benros – volume: 62 start-page: 8 issue: Suppl 15 year: 2001 ident: 10.5607/en.2018.27.3.189_ref1 publication-title: J Clin Psychiatry contributor: fullname: Sartorius – volume: 203 start-page: 204 year: 2016 ident: 10.5607/en.2018.27.3.189_ref18 publication-title: J Affect Disord doi: 10.1016/j.jad.2016.06.005 contributor: fullname: Carl – volume: 65 start-page: 732 year: 2009 ident: 10.5607/en.2018.27.3.189_ref38 publication-title: Biol Psychiatry doi: 10.1016/j.biopsych.2008.11.029 contributor: fullname: Miller – volume: 2017 start-page: 6280925 year: 2017 ident: 10.5607/en.2018.27.3.189_ref4 publication-title: Mediators Inflamm contributor: fullname: Choi – volume: 501 start-page: 933 year: 2018 ident: 10.5607/en.2018.27.3.189_ref15 publication-title: Biochem Biophys Res Commun doi: 10.1016/j.bbrc.2018.05.085 contributor: fullname: Li – volume: 252 start-page: 270 year: 2017 ident: 10.5607/en.2018.27.3.189_ref9 publication-title: Psychiatry Res doi: 10.1016/j.psychres.2017.03.012 contributor: fullname: Lavebratt – volume: 18 start-page: 356 year: 2015 ident: 10.5607/en.2018.27.3.189_ref24 publication-title: Iran J Basic Med Sci contributor: fullname: Guven – volume: 25 start-page: 706 year: 2011 ident: 10.5607/en.2018.27.3.189_ref10 publication-title: Brain Behav Immun doi: 10.1016/j.bbi.2011.01.011 contributor: fullname: Wang – volume: 590 start-page: 96 year: 2015 ident: 10.5607/en.2018.27.3.189_ref14 publication-title: Neurosci Lett doi: 10.1016/j.neulet.2015.01.081 contributor: fullname: Ming – volume: 28 start-page: 174 year: 2014 ident: 10.5607/en.2018.27.3.189_ref25 publication-title: J Biochem Mol Toxicol doi: 10.1002/jbt.21550 contributor: fullname: Prasanna – volume: 5 start-page: 21 year: 2015 ident: 10.5607/en.2018.27.3.189_ref5 publication-title: Biomedicine (Taipei) doi: 10.7603/s40681-015-0021-x contributor: fullname: Su – volume: 71 start-page: 140 year: 2015 ident: 10.5607/en.2018.27.3.189_ref6 publication-title: J Psychiatr Res doi: 10.1016/j.jpsychires.2015.10.006 contributor: fullname: Reid – volume: 101 start-page: 37 year: 2015 ident: 10.5607/en.2018.27.3.189_ref35 publication-title: Steroids doi: 10.1016/j.steroids.2015.05.010 contributor: fullname: Ali – volume: 42 start-page: 317 year: 2013 ident: 10.5607/en.2018.27.3.189_ref29 publication-title: Int J Oncol doi: 10.3892/ijo.2012.1709 contributor: fullname: Hwang – volume: 2018 start-page: 5198594 year: 2018 ident: 10.5607/en.2018.27.3.189_ref46 publication-title: Evid Based Complement Alternat Med contributor: fullname: Zhu – volume: 79 start-page: 776 year: 2016 ident: 10.5607/en.2018.27.3.189_ref37 publication-title: Biol Psychiatry doi: 10.1016/j.biopsych.2015.04.022 contributor: fullname: Brachman – volume: 309 start-page: 153 year: 2001 ident: 10.5607/en.2018.27.3.189_ref19 publication-title: Neurosci Lett doi: 10.1016/S0304-3940(01)02062-6 contributor: fullname: Von Frijtag – volume: 34 start-page: 1223 year: 2010 ident: 10.5607/en.2018.27.3.189_ref34 publication-title: Prog Neuropsychopharmacol Biol Psychiatry doi: 10.1016/j.pnpbp.2010.06.024 contributor: fullname: Yi – volume: 48 start-page: 135 year: 2014 ident: 10.5607/en.2018.27.3.189_ref32 publication-title: Prog Neuropsychopharmacol Biol Psychiatry doi: 10.1016/j.pnpbp.2013.10.002 contributor: fullname: Yi – volume: 92 start-page: 160 year: 1998 ident: 10.5607/en.2018.27.3.189_ref12 publication-title: J Neuroimmunol doi: 10.1016/S0165-5728(98)00199-4 contributor: fullname: Armario – volume: 163 start-page: 177 year: 2016 ident: 10.5607/en.2018.27.3.189_ref28 publication-title: Physiol Behav doi: 10.1016/j.physbeh.2016.05.017 contributor: fullname: Sadeghi – volume: 492 start-page: 493 year: 2017 ident: 10.5607/en.2018.27.3.189_ref22 publication-title: Biochem Biophys Res Commun doi: 10.1016/j.bbrc.2017.08.068 contributor: fullname: Kim – volume: 383 start-page: 93 year: 2009 ident: 10.5607/en.2018.27.3.189_ref55 publication-title: Biochem Biophys Res Commun doi: 10.1016/j.bbrc.2009.03.133 contributor: fullname: Min – volume: 71 start-page: e21984 year: 2017 ident: 10.5607/en.2018.27.3.189_ref58 publication-title: Synapse doi: 10.1002/syn.21984 contributor: fullname: Cuevas-Olguin – year: 2018 ident: 10.5607/en.2018.27.3.189_ref16 publication-title: Am J Hypertens contributor: fullname: Wang – volume: 64 start-page: 52 year: 2002 ident: 10.5607/en.2018.27.3.189_ref53 publication-title: Psychosom Med doi: 10.1097/00006842-200201000-00008 contributor: fullname: Dickens – volume: 4 start-page: 389 year: 1994 ident: 10.5607/en.2018.27.3.189_ref49 publication-title: Curr Opin Neurobiol doi: 10.1016/0959-4388(94)90101-5 contributor: fullname: Bear – volume: 5 start-page: 2438 year: 2014 ident: 10.5607/en.2018.27.3.189_ref21 publication-title: Food Funct doi: 10.1039/C4FO00346B contributor: fullname: Navaneethan – volume: 62 start-page: 419 year: 2012 ident: 10.5607/en.2018.27.3.189_ref13 publication-title: Neuropharmacology doi: 10.1016/j.neuropharm.2011.08.018 contributor: fullname: Kaster – volume: 11 start-page: 1169 year: 2008 ident: 10.5607/en.2018.27.3.189_ref47 publication-title: Int J Neuropsychopharmacol doi: 10.1017/S1461145708009309 contributor: fullname: Brunoni – volume: 14 start-page: 65 year: 2007 ident: 10.5607/en.2018.27.3.189_ref41 publication-title: Neuroimmunomodulation doi: 10.1159/000107420 contributor: fullname: Myint – volume: 31 start-page: 226 year: 2017 ident: 10.5607/en.2018.27.3.189_ref2 publication-title: Fundam Clin Pharmacol doi: 10.1111/fcp.12252 contributor: fullname: Braunstein – volume: 322 start-page: 138 year: 2017 ident: 10.5607/en.2018.27.3.189_ref31 publication-title: Behav Brain Res doi: 10.1016/j.bbr.2017.01.008 contributor: fullname: Kim – volume: 190 start-page: 124 year: 2018 ident: 10.5607/en.2018.27.3.189_ref57 publication-title: Chemosphere doi: 10.1016/j.chemosphere.2017.09.098 contributor: fullname: Li – volume: 5 start-page: 741 year: 2016 ident: 10.5607/en.2018.27.3.189_ref20 publication-title: ACS Synth Biol doi: 10.1021/acssynbio.6b00081 contributor: fullname: Calero – volume: 21 start-page: E1341 year: 2016 ident: 10.5607/en.2018.27.3.189_ref33 publication-title: Molecules doi: 10.3390/molecules21101341 contributor: fullname: Li – volume: 343 start-page: 1 year: 2017 ident: 10.5607/en.2018.27.3.189_ref17 publication-title: Neuroscience doi: 10.1016/j.neuroscience.2016.11.038 contributor: fullname: Zhou – volume: 11 start-page: 680 year: 2006 ident: 10.5607/en.2018.27.3.189_ref40 publication-title: Mol Psychiatry doi: 10.1038/sj.mp.4001805 contributor: fullname: Müller – volume: 29 start-page: 324 year: 2017 ident: 10.5607/en.2018.27.3.189_ref3 publication-title: Acta Neuropsychiatr doi: 10.1017/neu.2016.68 contributor: fullname: Kirkedal – volume: 11 start-page: 41 year: 2016 ident: 10.5607/en.2018.27.3.189_ref8 publication-title: Open Med (Wars) doi: 10.1515/med-2016-0009 contributor: fullname: Talarowska – volume: 13 start-page: 717 year: 2008 ident: 10.5607/en.2018.27.3.189_ref11 publication-title: Mol Psychiatry doi: 10.1038/sj.mp.4002055 contributor: fullname: Goshen |
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Title | Antidepressant-like Effects of p-Coumaric Acid on LPS-induced Depressive and Inflammatory Changes in Rats |
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