The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships

• Published in: The Journal of biological chemistry Vol. 262; no. 33; pp. 16060 - 16071
• Main Authors: Sweetser, D A, Birkenmeier, E H, Klisak, I J, Zollman, S, Sparkes, R S, Mohandas, T, Lusis, A J, Gordon, J I
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Elsevier Inc 25.11.1987; American Society for Biochemistry and Molecular Biology
• Subjects: Amino Acid Sequence; Animals; Base Sequence; Biological and medical sciences; Biotechnology; Carrier Proteins - genetics; Chromosome Mapping; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 4; DNA Restriction Enzymes; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fundamental and applied biological sciences. Psychology; Gene expression; Genes; Genetic engineering; Genetic Linkage; Genetic technics; Humans; Intestine, Small - metabolism; Liver - metabolism; Methods. Procedures. Technologies; Mice; Molecular and cellular biology; Molecular cloning; Molecular genetics; Molecular Sequence Data; Neoplasm Proteins; Nerve Tissue Proteins; Species Specificity; Transcription, Genetic; Tumor Suppressor Proteins; Human; Cell culture; Hybrid cell; Gut; Rodentia; Chromosome; Homology; Primary structure; Gene expression; Fatty acids; Binding protein; Vertebrata; Mammalia; Gene; Localization; Southern blotting; Intestinal fatty acid binding protein; Comparative study

Intestinal fatty acid binding protein (I-FABP) is believed to participate in the uptake, intracellular metabolism, and/or transport of long chain fatty acids within enterocytes. The 15.1-kDA rodent proteins is a member of a family of low Mr cytoplasmic proteins that have evolved to bind different li...