Human T-cell lymphotropic virus type I (HTLV-I) proviral DNA viral load among asymptomatic patients and patients with HTLV-I-associated myelopathy/tropical spastic paraparesis

• Published in: Brazilian journal of medical and biological research Vol. 38; no. 11; pp. 1643 - 1647
• Main Authors: Montanheiro, P.A., Penalva de Oliveira, A.C., Posada-Vergara, M.P., Milagres, A.C., Tauil, C., Marchiori, P.E., Duarte, A.J.S., Casseb, J.
• Format: Journal Article
• Language: English
• Published: Brazil Associação Brasileira de Divulgação Científica 01.11.2005
• Subjects: BIOLOGY; Case-Control Studies; DNA, Viral - analysis; DNA, Viral - genetics; DNA, Viral - immunology; HTLV-I; HTLV-I DNA viral load; HTLV-I-associated myelopathy; Human T-lymphotropic virus 1; Human T-lymphotropic virus 1 - genetics; Human T-lymphotropic virus 1 - immunology; Humans; Leukocytes, Mononuclear - immunology; MEDICINE, RESEARCH & EXPERIMENTAL; Paraparesis, Tropical Spastic - immunology; Paraparesis, Tropical Spastic - virology; Polymerase Chain Reaction; Proviruses - genetics; Proviruses - immunology; Viral Load; HTLV-I DNA viral load; HTLV-I; HTLV-I-associated myelopathy

To evaluate the human T-cell lymphotropic virus type I (HTLV-I) proviral DNA load among asymptomatic HTLV-I-infected carriers and patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), real time PCR using TaqMan probes for the pol gene was performed in two million periphe...