Incorporation of Copper-Doped Mesoporous Bioactive Glass Nanospheres in Experimental Dental Composites: Chemical and Mechanical Characterization

Experimental dental resin composites incorporating copper-doped mesoporous bioactive glass nanospheres (Cu-MBGN) were designed to impart antibacterial and remineralizing properties. The study evaluated the influence of Cu-MBGN on the mechanical properties and photopolymerization of resin composites....

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Published inMaterials Vol. 14; no. 10; p. 2611
Main Authors Marovic, Danijela, Haugen, Håvard J, Negovetic Mandic, Visnja, Par, Matej, Zheng, Kai, Tarle, Zrinka, Boccaccini, Aldo R
Format Journal Article
LanguageEnglish
Norwegian
Published Switzerland MDPI AG 17.05.2021
MDPI
Subjects
bioactive glass
Bioglass
Biological activity
Composite materials
Copper
Crack propagation
Curing
dental
Dental materials
Diamond pyramid hardness
Fillers
Flexural strength
Glass fiber reinforced plastics
Hydroxyapatite
Hypotheses
Mechanical properties
mesoporous
Modulus of rupture in bending
nanoparticles
Nanospheres
Photopolymerization
Polyesters
Polymerization
resin composites
Resins
Silicon dioxide
Sol-gel processes
Spectrum analysis
United Kingdom > UK
United States > US
Germany
copper
bioactive glass
resin composites
nanoparticles
dental
mesoporous
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Abstract Experimental dental resin composites incorporating copper-doped mesoporous bioactive glass nanospheres (Cu-MBGN) were designed to impart antibacterial and remineralizing properties. The study evaluated the influence of Cu-MBGN on the mechanical properties and photopolymerization of resin composites. Cu-MBGN were synthesized using a microemulsion-assisted sol-gel method. Increasing amounts of Cu-MBGN (0, 1, 5, and 10 wt %) were added to the organic polymer matrix with inert glass micro- and nanofillers while maintaining a constant resin/filler ratio. Six tests were performed: X-ray diffraction, scanning electron microscopy, flexural strength (FS), flexural modulus (FM), Vickers microhardness (MH), and degree of conversion (DC). FS and MH of Cu-MBGN composites with silica fillers showed no deterioration with aging, with statistically similar results at 1 and 28 days. FM was not influenced by the addition of Cu-MBGN but was reduced for all tested materials after 28 days. The specimens with 1 and 5% Cu-MBGN had the highest FS, FM, MH, and DC values at 28 days, while controls with 45S5 bioactive glass had the lowest FM, FS, and MH. DC was high for all materials (83.7-93.0%). Cu-MBGN composites with silica have a potential for clinical implementation due to high DC and good mechanical properties with adequate resistance to aging.
AbstractList Experimental dental resin composites incorporating copper-doped mesoporous bioactive glass nanospheres (Cu-MBGN) were designed to impart antibacterial and remineralizing properties. The study evaluated the influence of Cu-MBGN on the mechanical properties and photopolymerization of resin composites. Cu-MBGN were synthesized using a microemulsion-assisted sol-gel method. Increasing amounts of Cu-MBGN (0, 1, 5, and 10 wt %) were added to the organic polymer matrix with inert glass micro- and nanofillers while maintaining a constant resin/filler ratio. Six tests were performed: X-ray diffraction, scanning electron microscopy, flexural strength (FS), flexural modulus (FM), Vickers microhardness (MH), and degree of conversion (DC). FS and MH of Cu-MBGN composites with silica fillers showed no deterioration with aging, with statistically similar results at 1 and 28 days. FM was not influenced by the addition of Cu-MBGN but was reduced for all tested materials after 28 days. The specimens with 1 and 5% Cu-MBGN had the highest FS, FM, MH, and DC values at 28 days, while controls with 45S5 bioactive glass had the lowest FM, FS, and MH. DC was high for all materials (83.7-93.0%). Cu-MBGN composites with silica have a potential for clinical implementation due to high DC and good mechanical properties with adequate resistance to aging.
Author Negovetic Mandic, Visnja
Haugen, Håvard J
Marovic, Danijela
Tarle, Zrinka
Zheng, Kai
Boccaccini, Aldo R
Par, Matej
AuthorAffiliation 1 Department of Endodontics and Restorative Dentistry, School of Dental Medicine, University of Zagreb, 10000 Zagreb, Croatia; vnegovetic@sfzg.hr (V.N.M.); mpar@sfzg.hr (M.P.); tarle@sfzg.hr (Z.T.)
2 Department of Biomaterials, Institute of Clinical Dentistry, University of Oslo, 0455 Oslo, Norway; h.j.haugen@odont.uio.no
3 Department of Materials Science and Engineering, Institute of Biomaterials, University of Erlangen-Nuremberg, 91058 Erlangen, Germany; kai.zheng@fau.de (K.Z.); aldo.boccaccini@fau.de (A.R.B.)
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– name: 2 Department of Biomaterials, Institute of Clinical Dentistry, University of Oslo, 0455 Oslo, Norway; h.j.haugen@odont.uio.no
– name: 3 Department of Materials Science and Engineering, Institute of Biomaterials, University of Erlangen-Nuremberg, 91058 Erlangen, Germany; kai.zheng@fau.de (K.Z.); aldo.boccaccini@fau.de (A.R.B.)
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/34067788$$D View this record in MEDLINE/PubMed
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Keywords copper
bioactive glass
resin composites
nanoparticles
dental
mesoporous
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Snippet Experimental dental resin composites incorporating copper-doped mesoporous bioactive glass nanospheres (Cu-MBGN) were designed to impart antibacterial and...
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StartPage 2611
SubjectTerms bioactive glass
Bioglass
Biological activity
Composite materials
Copper
Crack propagation
Curing
dental
Dental materials
Diamond pyramid hardness
Fillers
Flexural strength
Glass fiber reinforced plastics
Hydroxyapatite
Hypotheses
Mechanical properties
mesoporous
Modulus of rupture in bending
nanoparticles
Nanospheres
Photopolymerization
Polyesters
Polymerization
resin composites
Resins
Silicon dioxide
Sol-gel processes
Spectrum analysis
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Title Incorporation of Copper-Doped Mesoporous Bioactive Glass Nanospheres in Experimental Dental Composites: Chemical and Mechanical Characterization
URI https://www.ncbi.nlm.nih.gov/pubmed/34067788
https://www.proquest.com/docview/2532644038/abstract/
https://search.proquest.com/docview/2536470043
http://hdl.handle.net/10852/86202
https://pubmed.ncbi.nlm.nih.gov/PMC8156461
https://doaj.org/article/3e6db1d41b52462083c9cc4adc843735
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