Intrathyroidal epithelial thymoma (ITET)/carcinoma showing thymus-like differentiation (CASTLE) exhibits CD5 immunoreactivity: new evidence for thymic differentiation

• Published in: Histopathology Vol. 32; no. 2; pp. 104 - 109
• Main Authors: DORFMAN, D. M, SHAHSAFAEI, A, MIYAUCHI, A
• Format: Journal Article
• Language: English
• Published: Oxford, U.K. and Cambridge, USA Blackwell Science Ltd 01.02.1998; Blackwell
• Subjects: Adult; Aged; Biological and medical sciences; Carcinoma - immunology; Carcinoma - pathology; CD5 Antigens - analysis; Cell Differentiation; Endocrinopathies; Epithelium - pathology; Female; Humans; immunohistochemistry; Male; Malignant tumors; Medical sciences; Middle Aged; squamous cell carcinoma; Thymoma - pathology; thymus; Thymus Gland - pathology; Thymus Neoplasms - immunology; Thymus Neoplasms - pathology; thyroid; Thyroid Neoplasms - immunology; Thyroid Neoplasms - pathology; Thyroid. Thyroid axis (diseases); Endocrinopathy; Human; Immunohistochemistry; Carcinoma; Thyroid diseases; Histiogenesis; Thyroid gland; Malignant tumor; Thymus pathology; Case study; Pathology; Adult; Malignant thymoma

Aims: Cases of intrathyroidal epithelial thymoma (ITET)/carcinoma showing thymus‐like differentiation (CASTLE) were examined for CD5 immunoreactivity, a feature of true thymic carcinoma, but not other thymic epithelial neoplasms or carcinomas of other sites. ITET/CASTLE, a rare, low‐grade malignant...