Role of the mechanotransductor PIEZO1 in megakaryocyte differentiation - Demagny, Julien; Poirault‐Chassac, Sonia; Ilsaint, Damtz Nehemie; Marchelli, Aurore; Gomila, Cathy; Ouled‐Haddou, Hakim; Collet, Louison; Le Guyader, Maïlys; Gaussem, Pascale; Garçon, Loïc; Bachelot‐Loza, Christilla (Journal of cellular and molecular medicine, 2024)
Keywords: Anemia, Hemolytic, Congenital - genetics; Anemia, Hemolytic, Congenital - metabolism; Anemia, Hemolytic, Congenital - pathology; Antigens, CD34 - metabolism; Automation; Blood; Blood Platelets - metabolism; Calcium - metabolism; Calcium influx; CD34 antigen; Cell activation; Cell culture; Cell differentiation; Cell Differentiation - genetics; Cell growth; Cell proliferation; Flow cytometry; Hematology; Hematopoietic stem cells; Hematopoietic Stem Cells - cytology; Hematopoietic Stem Cells - metabolism; Hemolytic anemia; Human health and pathology; Humans; Hydrops Fetalis - genetics; Hydrops Fetalis - metabolism; Hydrops Fetalis - pathology; Ion Channels - genetics; Ion Channels - metabolism; Life Sciences; Mechanical properties; Mechanotransduction, Cellular; Megakaryocytes; Megakaryocytes - cytology; Megakaryocytes - metabolism; Mortality; Mutation; Original; Phosphorylation; PIEZO1; proplatelet formation; Pyrazines; Shear stress; Thiadiazoles; Thrombopoiesis; Thrombopoiesis - genetics; proplatelet formation; PIEZO1; megakaryocytes