Plasmodium sexual differentiation: how to make a female

• Published in: Molecular microbiology Vol. 112; no. 6; pp. 1627 - 1631
• Main Authors: Ralph, Stuart A., Cortés, Alfred
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.12.2019; John Wiley & Sons
• Subjects: Differentiation; Eukaryotes; Females; Gametes; Gametocytes; Gene expression; Malalties de transmissió sexual; Malaria; Males; Maturation; Molecular machines; Mosquitoes; Parasites; Plasmodium; Protozoan diseases; Protozoosi; Regulatory proteins; Sex; Sex differentiation; Sexually transmitted diseases; Vector-borne diseases; Vertebrates

Summary Sexual development is integral to the transmission of Plasmodium parasites between vertebrates and mosquitos. Recent years have seen great advances in understanding the gene expression that underlies commitment of asexual parasites to differentiate into sexual gametocyte stages, then how the...