Effect of Early Rehabilitation in the Intensive Care Unit by a Dedicated Therapist Using a Rehabilitation Protocol: A Single-center Retrospective Study
Objectives: This study investigated retrospectively the effect of early rehabilitation in the intensive care unit (ICU) by a dedicated therapist using a rehabilitation protocol.Methods: The subjects comprised patients admitted to our emergency ICU. A dedicated therapist and a rehabilitation protocol...
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Published in | Progress in Rehabilitation Medicine Vol. 6; p. 20210030 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
The Japanese Association of Rehabilitation Medicine
01.01.2021
JARM |
Subjects | |
Online Access | Get full text |
ISSN | 2432-1354 2432-1354 |
DOI | 10.2490/prm.20210030 |
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Abstract | Objectives: This study investigated retrospectively the effect of early rehabilitation in the intensive care unit (ICU) by a dedicated therapist using a rehabilitation protocol.Methods: The subjects comprised patients admitted to our emergency ICU. A dedicated therapist and a rehabilitation protocol were instigated in April 2018. We enrolled 330 patients in phase I (April 2016–March 2018) and 383 patients in phase II (April 2018–March 2020). Patients in the ICU for only one night and pediatric patients were excluded. The following data were accessed from medical records: sex, height, age, Sequential Organ Failure Assessment, rehabilitation intervention, ventilation at admission, duration of mechanical ventilation, extubation, reintubation, tracheotomy, length of ICU stay, length of hospital stay, and outcome. The effectiveness of rehabilitation was assessed using the time from ICU admission to the first rehabilitation session, first sitting exercise, and first standing exercise. Clinical outcomes were analyzed separately for subjects discharged to home or transferred to another hospital.Results: The percentage of subjects undergoing rehabilitation intervention increased significantly from 23.4% to 56.7% (P<0.001) in phase II. Moreover, reintubation (P=0.045); the length of ICU stay (P=0.022); and the time from ICU admission to the first rehabilitation session (P<0.001), the first sitting exercise (P=0.001), and the first standing exercise (P=0.047) significantly decreased in phase II. Furthermore, the duration of mechanical ventilation (P=0.007) and the length of ICU stay (P=0.036) were significantly reduced in the transfer group.Conclusions: Although the effectiveness of early intervention was suggested, prospective multicenter studies are required to confirm this finding. |
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AbstractList | Objectives: This study investigated retrospectively the effect of early rehabilitation in the intensive care unit (ICU) by a dedicated therapist using a rehabilitation protocol.Methods: The subjects comprised patients admitted to our emergency ICU. A dedicated therapist and a rehabilitation protocol were instigated in April 2018. We enrolled 330 patients in phase I (April 2016–March 2018) and 383 patients in phase II (April 2018–March 2020). Patients in the ICU for only one night and pediatric patients were excluded. The following data were accessed from medical records: sex, height, age, Sequential Organ Failure Assessment, rehabilitation intervention, ventilation at admission, duration of mechanical ventilation, extubation, reintubation, tracheotomy, length of ICU stay, length of hospital stay, and outcome. The effectiveness of rehabilitation was assessed using the time from ICU admission to the first rehabilitation session, first sitting exercise, and first standing exercise. Clinical outcomes were analyzed separately for subjects discharged to home or transferred to another hospital.Results: The percentage of subjects undergoing rehabilitation intervention increased significantly from 23.4% to 56.7% (P<0.001) in phase II. Moreover, reintubation (P=0.045); the length of ICU stay (P=0.022); and the time from ICU admission to the first rehabilitation session (P<0.001), the first sitting exercise (P=0.001), and the first standing exercise (P=0.047) significantly decreased in phase II. Furthermore, the duration of mechanical ventilation (P=0.007) and the length of ICU stay (P=0.036) were significantly reduced in the transfer group.Conclusions: Although the effectiveness of early intervention was suggested, prospective multicenter studies are required to confirm this finding. This study investigated retrospectively the effect of early rehabilitation in the intensive care unit (ICU) by a dedicated therapist using a rehabilitation protocol.OBJECTIVESThis study investigated retrospectively the effect of early rehabilitation in the intensive care unit (ICU) by a dedicated therapist using a rehabilitation protocol.The subjects comprised patients admitted to our emergency ICU. A dedicated therapist and a rehabilitation protocol were instigated in April 2018. We enrolled 330 patients in phase I (April 2016-March 2018) and 383 patients in phase II (April 2018-March 2020). Patients in the ICU for only one night and pediatric patients were excluded. The following data were accessed from medical records: sex, height, age, Sequential Organ Failure Assessment, rehabilitation intervention, ventilation at admission, duration of mechanical ventilation, extubation, reintubation, tracheotomy, length of ICU stay, length of hospital stay, and outcome. The effectiveness of rehabilitation was assessed using the time from ICU admission to the first rehabilitation session, first sitting exercise, and first standing exercise. Clinical outcomes were analyzed separately for subjects discharged to home or transferred to another hospital.METHODSThe subjects comprised patients admitted to our emergency ICU. A dedicated therapist and a rehabilitation protocol were instigated in April 2018. We enrolled 330 patients in phase I (April 2016-March 2018) and 383 patients in phase II (April 2018-March 2020). Patients in the ICU for only one night and pediatric patients were excluded. The following data were accessed from medical records: sex, height, age, Sequential Organ Failure Assessment, rehabilitation intervention, ventilation at admission, duration of mechanical ventilation, extubation, reintubation, tracheotomy, length of ICU stay, length of hospital stay, and outcome. The effectiveness of rehabilitation was assessed using the time from ICU admission to the first rehabilitation session, first sitting exercise, and first standing exercise. Clinical outcomes were analyzed separately for subjects discharged to home or transferred to another hospital.The percentage of subjects undergoing rehabilitation intervention increased significantly from 23.4% to 56.7% (P<0.001) in phase II. Moreover, reintubation (P=0.045); the length of ICU stay (P=0.022); and the time from ICU admission to the first rehabilitation session (P<0.001), the first sitting exercise (P=0.001), and the first standing exercise (P=0.047) significantly decreased in phase II. Furthermore, the duration of mechanical ventilation (P=0.007) and the length of ICU stay (P=0.036) were significantly reduced in the transfer group.RESULTSThe percentage of subjects undergoing rehabilitation intervention increased significantly from 23.4% to 56.7% (P<0.001) in phase II. Moreover, reintubation (P=0.045); the length of ICU stay (P=0.022); and the time from ICU admission to the first rehabilitation session (P<0.001), the first sitting exercise (P=0.001), and the first standing exercise (P=0.047) significantly decreased in phase II. Furthermore, the duration of mechanical ventilation (P=0.007) and the length of ICU stay (P=0.036) were significantly reduced in the transfer group.Although the effectiveness of early intervention was suggested, prospective multicenter studies are required to confirm this finding.CONCLUSIONSAlthough the effectiveness of early intervention was suggested, prospective multicenter studies are required to confirm this finding. |
ArticleNumber | 20210030 |
Author | Komada, Ryo Tsujita, Yasuyuki Hisano, Tomoyuki Sakai, Kazutaka Miyai, Tamami Torimoto, Mayu Iwai, Kohji |
Author_xml | – sequence: 1 fullname: Sakai, Kazutaka organization: Division of Physical Therapy, Rehabilitation Units, Shiga University of Medical Science, Otsu, Japan – sequence: 1 fullname: Tsujita, Yasuyuki organization: Department of Critical and Intensive Care Medicine, Shiga University of Medical Science, Otsu, Japan – sequence: 1 fullname: Iwai, Kohji organization: Division of Physical Therapy, Rehabilitation Units, Shiga University of Medical Science, Otsu, Japan – sequence: 1 fullname: Torimoto, Mayu organization: Division of Physical Therapy, Rehabilitation Units, Shiga University of Medical Science, Otsu, Japan – sequence: 1 fullname: Hisano, Tomoyuki organization: Division of Physical Therapy, Rehabilitation Units, Shiga University of Medical Science, Otsu, Japan – sequence: 1 fullname: Komada, Ryo organization: Division of Physical Therapy, Rehabilitation Units, Shiga University of Medical Science, Otsu, Japan – sequence: 1 fullname: Miyai, Tamami organization: Division of Physical Therapy, Rehabilitation Units, Shiga University of Medical Science, Otsu, Japan |
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CitedBy_id | crossref_primary_10_1186_s12879_023_08151_w crossref_primary_10_1016_j_rehab_2024_101908 crossref_primary_10_1111_nicc_13143 crossref_primary_10_7759_cureus_31328 crossref_primary_10_15446_revfacmed_v71n2_98682 |
Cites_doi | 10.1186/s40560-016-0190-z 10.1097/CCM.0000000000003259 10.1007/s001340051292 10.2490/prm.20200027 10.1016/S0140-6736(09)60658-9 10.1136/thoraxjnl-2016-209858 10.1152/physrev.90100.2007 10.1155/2018/3654251 10.1371/journal.pone.0224565 10.1097/CCM.0000000000004382 10.1007/s13539-010-0010-6 10.1001/jama.2013.278481 10.1111/crj.12091 10.1016/S0140-6736(98)12251-1 10.12659/MSM.916210 10.1007/s00134-016-4612-0 10.3349/ymj.2018.59.7.843 10.1164/rccm.201208-1523CI 10.1056/NEJM200005183422002 10.5847/wjem.j.issn.1920-8642.2014.01.008 10.1183/09031936.00010206 |
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Drakulovic MB, Torres A, Bauer TT, Nicolas JM, Nogué S, Ferrer M: Supine body position as a risk factor for nosocomial pneumonia in mechanically ventilated patients: a randomised trial. Lancet 1999;354:1851–1858. PMID:10584721, DOI:10.1016/S0140-6736(98)12251-1 3. Kress JP, Pohlman AS, O’Connor MF, Hall JB: Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med 2000;342:1471–1477. PMID:10816184, DOI:10.1056/NEJM200005183422002 7. Taito S, Sanui M, Yasuda H, Shime N, Lefor AK, Japanese Society of Education for Physicians and Trainees in Intensive Care (JSEPTIC) Clinical Trial Group: Current rehabilitation practices in intensive care units: a preliminary survey by the Japanese Society of Education for Physicians and Trainees in Intensive Care (JSEPTIC) Clinical Trial Group. J Intensive Care 2016;4:66. PMID:27800164, DOI:10.1186/s40560-016-0190-z 6. Norrenberg M, Vincent JL European Society of Intensive Care Medicine: A profile of European intensive care unit physiotherapists. Intensive Care Med 2000;26:988–994. PMID:10990117, DOI:10.1007/s001340051292 11 12 13 14 15 16 17 18 19 1 2 3 4 5 6 7 8 9 20 10 21 |
References_xml | – reference: 3. Kress JP, Pohlman AS, O’Connor MF, Hall JB: Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med 2000;342:1471–1477. PMID:10816184, DOI:10.1056/NEJM200005183422002 – reference: 7. Taito S, Sanui M, Yasuda H, Shime N, Lefor AK, Japanese Society of Education for Physicians and Trainees in Intensive Care (JSEPTIC) Clinical Trial Group: Current rehabilitation practices in intensive care units: a preliminary survey by the Japanese Society of Education for Physicians and Trainees in Intensive Care (JSEPTIC) Clinical Trial Group. J Intensive Care 2016;4:66. PMID:27800164, DOI:10.1186/s40560-016-0190-z – reference: 4. Pang Y, Li H, Zhao L, Zhang C: An established early rehabilitation therapy demonstrating higher efficacy and safety for care of intensive care unit patients. Med Sci Monit 2019;25:7052–7058. PMID:31537777, DOI:10.12659/MSM.916210 – reference: 12. Dong Z, Yu B, Sun Y, Fang W, Li L: Effects of early rehabilitation therapy on patients with mechanical ventilation. World J Emerg Med 2014;5:48–52. PMID:25215147, DOI:10.5847/wjem.j.issn.1920-8642.2014.01.008 – reference: 14. Tipping CJ, Harrold M, Holland A, Romero L, Nisbet T, Hodgson CL: The effects of active mobilisation and rehabilitation in ICU on mortality and function: a systematic review. Intensive Care Med 2017;43:171–183. PMID:27864615, DOI:10.1007/s00134-016-4612-0 – reference: 9. Boles JM, Bion J, Connors A, Herridge M, Marsh B, Melot C, Pearl R, Silverman H, Stanchina M, Vieillard-Baron A, Welte T: Weaning from mechanical ventilation. Eur Respir J 2007;29:1033–1056. PMID:17470624, DOI:10.1183/09031936.00010206 – reference: 15. Waldauf P, Jiroutková K, Krajčová A, Puthucheary Z, Duška F: Effects of rehabilitation interventions on clinical outcomes in critically ill patients: systematic review and meta-analysis of randomized controlled trials. Crit Care Med 2020;48:1055–1065. – reference: 20. Pedersen BK, Febbraio MA: Muscle as an endocrine organ: focus on muscle-derived interleukin-6. Physiol Rev 2008;88:1379–1406. PMID:18923185, DOI:10.1152/physrev.90100.2007 – reference: 1. Drakulovic MB, Torres A, Bauer TT, Nicolas JM, Nogué S, Ferrer M: Supine body position as a risk factor for nosocomial pneumonia in mechanically ventilated patients: a randomised trial. Lancet 1999;354:1851–1858. PMID:10584721, DOI:10.1016/S0140-6736(98)12251-1 – reference: 2. Devlin JW, Skrobik Y, Gélinas C, Needham DM, Slooter AJ, Pandharipande PP, Watson PL, Weinhouse GL, Nunnally ME, Rochwerg B, Balas MC, van den Boogaard M, Bosma KJ, Brummel NE, Chanques G, Denehy L, Drouot X, Fraser GL, Harris JE, Joffe AM, Kho ME, Kress JP, Lanphere JA, McKinley S, Neufeld KJ, Pisani MA, Payen JF, Pun BT, Puntillo KA, Riker RR, Robinson BR, Shehabi Y, Szumita PM, Winkelman C, Centofanti JE, Price C, Nikayin S, Misak CJ, Flood PD, Kiedrowski K, Alhazzani W: Executive summary: clinical practice guidelines for the prevention and management of pain, agitation/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU. Crit Care Med 2018;46:1532–1548. PMID:30113371, DOI:10.1097/CCM.0000000000003259 – reference: 21. Schweickert WD, Pohlman MC, Pohlman AS, Nigos C, Pawlik AJ, Esbrook CL, Spears L, Miller M, Franczyk M, Deprizio D, Schmidt GA, Bowman A, Barr R, McCallister KE, Hall JB, Kress JP: Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet 2009;373:1874–1882. PMID:19446324, DOI:10.1016/S0140-6736(09)60658-9 – reference: 13. Yosef-Brauner O, Adi N, Ben Shahar T, Yehezkel E, Carmeli E: Effect of physical therapy on muscle strength, respiratory muscles and functional parameters in patients with intensive care unit-acquired weakness. Clin Respir J 2015;9:1–6. PMID:24345055, DOI:10.1111/crj.12091 – reference: 17. Ahn JY, Song JE, Ann HW, Jeon Y, Ahn MY, Jung IY, Kim MH, Jeong W, Jeong SJ, Ku NS, Kim JM, Na S, Cho SR, Choi JY: Effects of early exercise rehabilitation on functional recovery in patients with severe sepsis. Yonsei Med J 2018;59:843–851. PMID:30091317, DOI:10.3349/ymj.2018.59.7.843 – reference: 10. Thille AW, Richard JC, Brochard L: The decision to extubate in the intensive care unit. Am J Respir Crit Care Med 2013;187:1294–1302. PMID:23641924, DOI:10.1164/rccm.201208-1523CI – reference: 6. Norrenberg M, Vincent JL European Society of Intensive Care Medicine: A profile of European intensive care unit physiotherapists. Intensive Care Med 2000;26:988–994. PMID:10990117, DOI:10.1007/s001340051292 – reference: 8. Matsuki R, Kojima N, Watanabe K, Hotta A, Kubori Y, Oura K, Morisawa T, Koyama H, Ebisu T, Hashino T: Impact of a rehabilitation protocol and a dedicated therapist in the intensive care unit on physical function and activities of daily living. Prog Rehabil Med 2020. doi: DOI:10.2490/prm.20200027 – reference: 18. 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Title | Effect of Early Rehabilitation in the Intensive Care Unit by a Dedicated Therapist Using a Rehabilitation Protocol: A Single-center Retrospective Study |
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