High Prevalence and Predominance of Hepatitis Delta Virus Genotype 1 Infection in Cameroon

• Published in: Journal of Clinical Microbiology Vol. 49; no. 3; pp. 1162 - 1164
• Main Authors: Foupouapouognigni, Yacouba, Noah, Dominique Noah, Sartre, Michèle Tagni, Njouom, Richard
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.03.2011
• Series: Notes
• Subjects: Adult; Biological and medical sciences; Cameroon - epidemiology; Cluster Analysis; Epidemiology; Female; Fundamental and applied biological sciences. Psychology; Genotype; Hepatitis Antibodies - blood; Hepatitis B - complications; Hepatitis B virus; Hepatitis D - epidemiology; Hepatitis D - virology; Hepatitis D virus; Hepatitis Delta Virus - classification; Hepatitis Delta Virus - genetics; Hepatitis Delta Virus - isolation & purification; Humans; Male; Microbiology; Miscellaneous; Molecular Sequence Data; Phylogeny; Polymorphism, Genetic; RNA, Viral - genetics; Sequence Analysis, DNA; Seroepidemiologic Studies; Virology; Cameroon; Central Africa; Sub-Saharan Africa; Africa; Virus; Hepatitis D virus; Genotype; Prevalence; Epidemiology; Tropical zone

Antibodies to the hepatitis delta virus (HDV) were found in 17.6% of 233 hepatitis B virus surface antigen-positive subjects in Cameroon. Phylogenetic analyses showed the presence of HDV-1, HDV-5, HDV-6, and HDV-7 genotypes. These results enrich the limited data on HDV prevalence and molecular diver...