Efficacy and safety of methimazole ointment for patients with hyperthyroidism

• Published in: Environmental toxicology and pharmacology Vol. 36; no. 3; pp. 1109 - 1112
• Main Authors: Wu, Xi, Liu, Hong, Zhu, Xixing, Shen, Jun, Shi, Yongquan, Liu, Zhimin, Gu, Mingjun, Song, Zhimin
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.11.2013
• Subjects: Adolescent; Adult; adverse effects; Aged; Antithyroid Agents - administration & dosage; Antithyroid Agents - adverse effects; Antithyroid Agents - therapeutic use; blood serum; Emergency; Female; Humans; Hyperthyroidism; Hyperthyroidism - blood; Hyperthyroidism - drug therapy; liver; Male; Methimazole; Methimazole - administration & dosage; Methimazole - adverse effects; Methimazole - therapeutic use; Middle Aged; monitoring; Ointment; Ointments; patients; Thyroid Hormones - blood; Transdermal administration; triiodothyronine; Young Adult; Methimazole; Transdermal administration; Ointment; Hyperthyroidism

•Efficacy and safety of methimazole ointment on hyperthyroidism was observed.•Methimazole ointment has similar clinical efficacy as oral tablets.•Methimazole ointment causes fewer systemic adverse effects. Oral methimazole has been widely used to treat hyperthyroidism, but its usage is restricted by...