Analysis of the in vitro and in vivo effects of photodynamic therapy on prostate cancer by using new photosensitizers, protoporphyrin IX-polyamine derivatives - Fidanzi-Dugas, Chloë; Liagre, Bertrand; Chemin, Guillaume; Perraud, Aurélie; Carrion, Claire; Couquet, Claude-Yves; Granet, Robert; Sol, Vincent; Léger, David Yannick (Biochimica et biophysica acta. General subjects, 2017)
Keywords: Animals; Apoptosis; Apoptosis - drug effects; Cancer; cell communication; Cell Line, Tumor; CHO Cells; Cricetulus; Cyclooxygenase; death; DNA fragmentation; enzyme-linked immunosorbent assay; gels; Humans; in vivo studies; Life Sciences; Male; neoplasm cells; Photochemotherapy; Photodynamic therapy; photosensitizing agents; Photosensitizing Agents - therapeutic use; phototoxicity; polyamines; Polyamines - pharmacology; Polyamines - therapeutic use; Porphyrin; Prostate cancer; prostatic neoplasms; Prostatic Neoplasms - drug therapy; Prostatic Neoplasms - pathology; protoporphyrin; Protoporphyrins - pharmacology; Protoporphyrins - therapeutic use; Reactive Oxygen Species - metabolism; therapeutics; tissues; transcription factor NF-kappa B; Xenograft Model Antitumor Assays; PpIX-dSd; PDT; PGE2; PS; Photodynamic therapy; COX-2; PpIX; PTS; PA; PpIX-PA; NAC; Cyclooxygenase; Porphyrin; ALA; PpIX-dSm; ROS; Prostate cancer; Apoptosis