A Quantitative Method to Monitor Reactive Oxygen Species Production by Electron Paramagnetic Resonance in Physiological and Pathological Conditions

• Published in: Oxidative medicine and cellular longevity Vol. 2014; no. 2014; pp. 1 - 10
• Main Authors: Porcelli, Simone, Montorsi, Michela, Gussoni, Maristella, Mrakic-Sposta, Simona, Vezzoli, Alessandra
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2014; John Wiley & Sons, Inc
• Subjects: Adult; Aged; Aging; Analysis; Antioxidants; Biological markers; Biomarkers; Blood Chemical Analysis - methods; Disease; Electron Spin Resonance Spectroscopy - methods; Female; Free radicals; Humans; Lipids; Male; Methods; Middle Aged; NMR; Nuclear magnetic resonance; Oxidation-Reduction; Oxidative stress; Oxidative Stress - physiology; Oxygen; Physiological aspects; Physiology; Plasma; Proteins; Reactive oxygen species; Reactive Oxygen Species - analysis; Reactive Oxygen Species - metabolism; Signal transduction; Young Adult; Italy

The growing interest in the role of Reactive Oxygen Species (ROS) and in the assessment of oxidative stress in health and disease clashes with the lack of consensus on reliable quantitative noninvasive methods applicable. The study aimed at demonstrating that a recently developed Electron Paramagnet...