Noninvasive Detection of Nonalcoholic Steatohepatitis Using Clinical Markers and Circulating Levels of Lipids and Metabolites - Zhou, You; Orešič, Matej; Leivonen, Marja; Gopalacharyulu, Peddinti; Hyysalo, Jenni; Arola, Johanna; Verrijken, An; Francque, Sven; Van Gaal, Luc; Hyötyläinen, Tuulia; Yki-Järvinen, Hannele (Clinical gastroenterology and hepatology, 2016)
Keywords: Adolescent; Adult; Aged; Biomarkers; Diagnosis; Diagnostic Tests, Routine - methods; Female; Gastroenterology and Hepatology; Genotyping Techniques - methods; Humans; Lipids - blood; Liver; Male; Mass Spectrometry - methods; Metabolomics; Middle Aged; Non-alcoholic Fatty Liver Disease - diagnosis; Nonalcoholic Fatty Liver Disease; Plasma - chemistry; Prediction; Triglycerides; Young Adult; Val; Ser; NAFLD; Ile; Liver; AUROC; Glu; HDL; Gly; TOFMS; Diagnosis; GC; NAFL; AST; CI; MS; Prediction; IR; Triglycerides; fP; NASH; Tyr; fS; Lip; LysoPC; MetS; TG; PE; UPLC; Nonalcoholic Fatty Liver Disease; LC; PNPLA3; Leu; MET; serine; fasting plasma; high-density lipoprotein; isoleucine; nonalcoholic steatohepatitis; glycine; ultra-performance liquid chromatography; glutamate; leucine; nonalcoholic fatty liver; patatin-like phospholipase domain-containing protein 3; metabolic syndrome; tyrosine; lipidomics; triacylglycerol; fasting serum; gas chromatography; lysophosphatidylcholines; mass spectrometry; insulin resistance; area under the receiver operating characteristic curve; lipid cluster; time-of-flight mass spectrometry; aspartate aminotransferase; metabolomic; phosphatidylethanolamine; confidence interval; valine