A novel splice variant of FcγRIIa: A risk factor for anaphylaxis in patients with hypogammaglobulinemia - van der Heijden, Joris; Geissler, Judy; van Mirre, Edwin; van Deuren, Marcel; van der Meer, Jos W.M.; Salama, Abdulgabar; van den Berg, Timo K.; Roos, Dirk; Kuijpers, Taco W. (Journal of allergy and clinical immunology, 2013)
Keywords: Adult; adverse effects; Agammaglobulinemia - etiology; Agammaglobulinemia - genetics; Agammaglobulinemia - immunology; alleles; Allergy and Immunology; Anaphylaxis; Anaphylaxis - complications; Anaphylaxis - genetics; Anaphylaxis - immunology; Animals; antibodies; antigen-antibody complex; calcium; common variable immunodeficiency; DNA; elastase; exons; Fcγ receptors; Female; heterozygosity; Humans; idiopathic thrombocytopenia; immunoglobulin A; immunoglobulin G; immunosuppression; intravenous immunoglobulin; intravenous injection; Kawasaki disease; Male; messenger RNA; Mice; mononuclear leukocytes; mutation; neutrophils; Neutrophils - immunology; Neutrophils - pathology; patients; Protein Isoforms - immunology; quantitative polymerase chain reaction; Receptors, IgG - genetics; Risk Factors; screening; splice variant; thrombocytopenia; IMIg; Fcγ receptors; [Ca2+]i; fMLP; ITP; IVIg; common variable immunodeficiency; elastase; CVID; FITC; Anaphylaxis; Kawasaki disease; SNP; KD; intravenous immunoglobulin; splice variant; neutrophils; FcγR; idiopathic thrombocytopenia; Fluorescein isothiocyanate; N-formyl-methionyl-leucyl-phenylalanine; Fcγ receptor; [Ca 2+] i; Intramuscular immunoglobulin; Single nucleotide polymorphism; Intracellular Ca 2+ ions