Deep Learning-Enhanced Hand Grip and Release Test for Degenerative Cervical Myelopathy: Shortening Assessment Duration to 6 Seconds

• Published in: Neurospine Vol. 21; no. 1; pp. 46 - 56
• Main Authors: Ye, Yongyu, Chang, Yunbing, Wu, Weihao, Liao, Tianying, Yu, Tao, Chen, Chong, Yu, Zhengran, Chen, Junying, Liang, Guoyan
• Format: Journal Article
• Language: English
• Published: Korea (South) Korean Spinal Neurosurgery Society 01.03.2024; 대한척추신경외과학회
• Subjects: 10-second grip and release test; deep learning; degenerative cervical myelopathy; diagnostic performance; Original; shortened assessment duration; 신경외과학; Deep learning; Degenerative cervical myelopathy; Diagnostic performance; Shortened assessment duration; 10-Second grip and release test
• DOI: 10.14245/ns.2347326.663
• ISSN: 2586-6583

Objective: Hand clumsiness and reduced hand dexterity can signal early signs of degenerative cervical myelopathy (DCM). While the 10-second grip and release (10-s G&R) test is a common clinical tool for evaluating hand function, a more accessible method is warranted. This study explores the use of deep learning-enhanced hand grip and release test (DL-HGRT) for predicting DCM and evaluates its capability to reduce the duration of the 10-s G&R test.Methods: The retrospective study included 508 DCM patients and 1,194 control subjects. Propensity score matching (PSM) was utilized to minimize the confounding effects related to age and sex. Videos of the 10-s G&R test were captured using a smartphone application. The 3D-MobileNetV2 was utilized for analysis, generating a series of parameters. Additionally, receiver operating characteristic curves were employed to assess the performance of the 10-s G&R test in predicting DCM and to evaluate the effectiveness of a shortened testing duration.Results: Patients with DCM exhibited impairments in most 10-s G&R test parameters. Before PSM, the number of cycles achieved the best diagnostic performance (area under the curve [AUC], 0.85; sensitivity, 80.12%; specificity, 74.29% at 20 cycles), followed by average grip time. Following PSM for age and gender, the AUC remained above 0.80. The average grip time achieved the highest AUC of 0.83 after 6 seconds, plateauing with no significant improvement in extending the duration to 10 seconds, indicating that 6 seconds is an adequate timeframe to efficiently evaluate hand motor dysfunction in DCM based on DL-HGRT.Conclusion: DL-HGRT demonstrates potential as a promising supplementary tool for predicting DCM. Notably, a testing duration of 6 seconds appears to be sufficient for accurate assessment, enhancing the test more feasible and practical without compromising diagnostic performance.