Neuron tracing in perspective

• Published in: Cytometry. Part A Vol. 77A; no. 7; pp. 693 - 704
• Main Author: Meijering, Erik
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.07.2010
• Subjects: Algorithms; Animals; bioimage informatics; Computer Simulation; Databases, Factual; digital reconstruction; Image Processing, Computer-Assisted - instrumentation; Image Processing, Computer-Assisted - methods; image segmentation; Imaging, Three-Dimensional - instrumentation; Imaging, Three-Dimensional - methods; neuroinformatics; neuron tracing; Neurons - cytology; neuroscience; pattern recognition; quantitative image analysis; Software; software tools; Staining and Labeling - methods

The study of the structure and function of neuronal cells and networks is of crucial importance in the endeavor to understand how the brain works. A key component in this process is the extraction of neuronal morphology from microscopic imaging data. In the past four decades, many computational meth...